Methods For Modulating Dna Repair Outcomes


Ontology type: sgo:Patent     


Patent Info

DATE

2017-08-31T00:00

AUTHORS

CAPURSO DANIEL , MAY ANDREW P , VAN OVERBEEK MEGAN

ABSTRACT

Methods for gene editing and predicting non-random editing events are described. The methods use Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) systems to characterize and manipulate DNA repair outcomes at Cas-initiated double-strand breaks (DSBs) to anticipate functional outcomes.

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