Assays For Massively Combinatorial Perturbation Profiling And Cellular Circuit Reconstruction


Ontology type: sgo:Patent     


Patent Info

DATE

2017-05-04T00:00

AUTHORS

REGEV, AVIV , ADAMSON, Brittany , CLEARY, BRIAN , CONG, LE , DIXIT, Atray , GAUBLOMME, Jellert , LANDER, ERIC, S. , NORMAN, THOMAS , PAMAS, Oren , ROZENBLATT-ROSEN, Orit , SHALEK, Alexander, K. , WEISSMAN, JONATHAN

ABSTRACT

The present invention provides tools and methods for the systematic analysis of genetic interactions, including higher order interactions. The present invention provides tools and methods for combinatorial probing of cellular circuits, for dissecting cellular circuitry, for delineating molecular pathways, and/or for identifying relevant targets for therapeutics development.

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