Method Of Blocking Transmission Of Malarial Parasite


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

MCKEW, JOHN C. , ZHENG, WEI , WILLIAMSON, Kim C. , HUANG, WENWEI , SUN, WEI , TANAKA, TAKESHI , DEHDASHTI, Seameen Jean , SOUTHALL, NOEL TERRENCE , MAGLE, Crystal Tobin , HUANG, Xiuli , PATEL, Paresma Rasiklal , KIM, MYUNGHOON

ABSTRACT

The invention provides a method of blocking transmission of a Plasmodium parasite and a method of treating or preventing malaria comprising administering to an animal an effective amount of a first compound of formula I: wherein A, B, R1, R2, R10, and R11 are described herein, either alone or in combination with a second compound selected from elesclomol, NSC 174938, NVP-AUY922, Maduramicin, Narasin, Alvespimycin, Omacetaxine, Thiram, Zinc pyrithione, Phanquinone, Bortezomib, Salinomycin sodium, Monensin sodium, Dipyrithione, Dicyclopentamethylene-thiuram disulfide, YM155, Withaferin A, Adriamycin, Romidepsin, AZD-1 152-HQPA, CAY10581, Plicamycin, CUDC-101, Auranofin, Trametinib, GSK-458, Afatinib, and Panobinostat. More... »

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/3114", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "name": "MCKEW, JOHN C.", 
        "type": "Person"
      }, 
      {
        "name": "ZHENG, WEI", 
        "type": "Person"
      }, 
      {
        "name": "WILLIAMSON, Kim C.", 
        "type": "Person"
      }, 
      {
        "name": "HUANG, WENWEI", 
        "type": "Person"
      }, 
      {
        "name": "SUN, WEI", 
        "type": "Person"
      }, 
      {
        "name": "TANAKA, TAKESHI", 
        "type": "Person"
      }, 
      {
        "name": "DEHDASHTI, Seameen Jean", 
        "type": "Person"
      }, 
      {
        "name": "SOUTHALL, NOEL TERRENCE", 
        "type": "Person"
      }, 
      {
        "name": "MAGLE, Crystal Tobin", 
        "type": "Person"
      }, 
      {
        "name": "HUANG, Xiuli", 
        "type": "Person"
      }, 
      {
        "name": "PATEL, Paresma Rasiklal", 
        "type": "Person"
      }, 
      {
        "name": "KIM, MYUNGHOON", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1177/1087057112458152", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003386316"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0910040106", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003648417"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/644645", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009646480"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nchembio.215", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009958901", 
          "https://doi.org/10.1038/nchembio.215"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1086/503051", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015282842"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0702136104", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019440020"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-09-3360", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019637270"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0166-6851(82)90035-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020417610"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-12-1702", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026359958"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0802982105", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026974218"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.molbiopara.2013.02.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028431117"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature09099", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042393051", 
          "https://doi.org/10.1038/nature09099"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nchembio.70", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044068305", 
          "https://doi.org/10.1038/nchembio.70"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/infdis/jir037", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052025999"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1078-0432.ccr-10-1927", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052694111"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/0008-5472.can-07-5256", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053497663"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jm101144f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055951937"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jm101520v", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055952094"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1205216", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062464676"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "description": "

The invention provides a method of blocking transmission of a Plasmodium parasite and a method of treating or preventing malaria comprising administering to an animal an effective amount of a first compound of formula I: wherein A, B, R1, R2, R10, and R11 are described herein, either alone or in combination with a second compound selected from elesclomol, NSC 174938, NVP-AUY922, Maduramicin, Narasin, Alvespimycin, Omacetaxine, Thiram, Zinc pyrithione, Phanquinone, Bortezomib, Salinomycin sodium, Monensin sodium, Dipyrithione, Dicyclopentamethylene-thiuram disulfide, YM155, Withaferin A, Adriamycin, Romidepsin, AZD-1 152-HQPA, CAY10581, Plicamycin, CUDC-101, Auranofin, Trametinib, GSK-458, Afatinib, and Panobinostat.

", "id": "sg:patent.WO-2015073804-A2", "keywords": [ "transmission", "malarial parasite", "invention", "method", "Plasmodium parasite", "malaria", "animal", "first compound", "formula", "wherein", "compound", "NVP", "zinc", "bortezomib", "sodium", "monensin", "disulfide", "doxorubicin", "romidepsin" ], "name": "METHOD OF BLOCKING TRANSMISSION OF MALARIAL PARASITE", "recipient": [ { "id": "https://www.grid.ac/institutes/grid.164971.c", "type": "Organization" } ], "sameAs": [ "https://app.dimensions.ai/details/patent/WO-2015073804-A2" ], "sdDataset": "patents", "sdDatePublished": "2019-03-07T15:34", "sdLicense": "https://scigraph.springernature.com/explorer/license/", "sdPublisher": { "name": "Springer Nature - SN SciGraph project", "type": "Organization" }, "sdSource": "s3://com.uberresearch.data.dev.patents-pipeline/full_run_10/sn-export/5eb3e5a348d7f117b22cc85fb0b02730/0000100128-0000348334/json_export_b65d5aab.jsonl", "type": "Patent" } ]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/patent.WO-2015073804-A2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/patent.WO-2015073804-A2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/patent.WO-2015073804-A2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/patent.WO-2015073804-A2'


 

This table displays all metadata directly associated to this object as RDF triples.

144 TRIPLES      14 PREDICATES      51 URIs      26 LITERALS      2 BLANK NODES

Subject Predicate Object
1 sg:patent.WO-2015073804-A2 schema:about anzsrc-for:3114
2 schema:author N381e3f6a39184975ad038ffb7c8df87c
3 schema:citation sg:pub.10.1038/nature09099
4 sg:pub.10.1038/nchembio.215
5 sg:pub.10.1038/nchembio.70
6 https://doi.org/10.1016/0166-6851(82)90035-4
7 https://doi.org/10.1016/j.molbiopara.2013.02.005
8 https://doi.org/10.1021/jm101144f
9 https://doi.org/10.1021/jm101520v
10 https://doi.org/10.1073/pnas.0702136104
11 https://doi.org/10.1073/pnas.0802982105
12 https://doi.org/10.1073/pnas.0910040106
13 https://doi.org/10.1086/503051
14 https://doi.org/10.1086/644645
15 https://doi.org/10.1093/infdis/jir037
16 https://doi.org/10.1126/science.1205216
17 https://doi.org/10.1158/0008-5472.can-07-5256
18 https://doi.org/10.1158/0008-5472.can-09-3360
19 https://doi.org/10.1158/0008-5472.can-12-1702
20 https://doi.org/10.1158/1078-0432.ccr-10-1927
21 https://doi.org/10.1177/1087057112458152
22 schema:description <p num="0000">The invention provides a method of blocking transmission of a Plasmodium parasite and a method of treating or preventing malaria comprising administering to an animal an effective amount of a first compound of formula I: wherein A, B, R<sup>1</sup>, R<sup>2</sup>, R<sup>10</sup>, and R<sup>11</sup> are described herein, either alone or in combination with a second compound selected from elesclomol, NSC 174938, NVP-AUY922, Maduramicin, Narasin, Alvespimycin, Omacetaxine, Thiram, Zinc pyrithione, Phanquinone, Bortezomib, Salinomycin sodium, Monensin sodium, Dipyrithione, Dicyclopentamethylene-thiuram disulfide, YM155, Withaferin A, Adriamycin, Romidepsin, AZD-1 152-HQPA, CAY10581, Plicamycin, CUDC-101, Auranofin, Trametinib, GSK-458, Afatinib, and Panobinostat.</p>
23 schema:keywords NVP
24 Plasmodium parasite
25 animal
26 bortezomib
27 compound
28 disulfide
29 doxorubicin
30 first compound
31 formula
32 invention
33 malaria
34 malarial parasite
35 method
36 monensin
37 romidepsin
38 sodium
39 transmission
40 wherein
41 zinc
42 schema:name METHOD OF BLOCKING TRANSMISSION OF MALARIAL PARASITE
43 schema:recipient https://www.grid.ac/institutes/grid.164971.c
44 schema:sameAs https://app.dimensions.ai/details/patent/WO-2015073804-A2
45 schema:sdDatePublished 2019-03-07T15:34
46 schema:sdLicense https://scigraph.springernature.com/explorer/license/
47 schema:sdPublisher N78efa9079213413d96be858965760696
48 sgo:license sg:explorer/license/
49 sgo:sdDataset patents
50 rdf:type sgo:Patent
51 N0effd3106e964fac89704f80ea331a15 schema:name DEHDASHTI, Seameen Jean
52 rdf:type schema:Person
53 N28fcf4d640154afe90afe5ccc40ddae9 schema:name ZHENG, WEI
54 rdf:type schema:Person
55 N2d14af3133484fbe8111e7e8f274d670 schema:name HUANG, Xiuli
56 rdf:type schema:Person
57 N381e3f6a39184975ad038ffb7c8df87c rdf:first Nfa75d46f36604ffdbb96d08c7302db79
58 rdf:rest N42057e8a55ec4e968a423acadc7da0cf
59 N42057e8a55ec4e968a423acadc7da0cf rdf:first N28fcf4d640154afe90afe5ccc40ddae9
60 rdf:rest N6e6e91e8d9ba45c584ca786a1ce11ea8
61 N4ba5615d1bdf4861a432495f698ea6a4 schema:name PATEL, Paresma Rasiklal
62 rdf:type schema:Person
63 N4cd31ba2ac0e4d4d8d95da1a93a3f3f1 rdf:first N9226bddf2f824abd9a8cf79a0eb429e0
64 rdf:rest N56d81a944a2a47e4a838a2055bfad7db
65 N56bd42b5e9c24875a1e90ed47b230adb rdf:first Nd956ca60c9ed4fbda6fb183706f41891
66 rdf:rest N6b197b18fa1945708103cd73d1282e79
67 N56d81a944a2a47e4a838a2055bfad7db rdf:first Nea081f9977df41b0ac79e4fadb1387d8
68 rdf:rest N971d9679ca7441a28b206d9713068f8a
69 N6b197b18fa1945708103cd73d1282e79 rdf:first Naeb87f6bc6bb4fe9ad932adce77d913f
70 rdf:rest Ne359bfd7fc3749bab51aa8b186567710
71 N6c12c107c9774b7fad2006952860bb83 rdf:first Nd6894054d3174591804d5ae79be4213b
72 rdf:rest rdf:nil
73 N6e6e91e8d9ba45c584ca786a1ce11ea8 rdf:first N887de8c79da74dad886fb1be91a29a01
74 rdf:rest Nabe6f0e5659849a894e96dff72c611f6
75 N78efa9079213413d96be858965760696 schema:name Springer Nature - SN SciGraph project
76 rdf:type schema:Organization
77 N887de8c79da74dad886fb1be91a29a01 schema:name WILLIAMSON, Kim C.
78 rdf:type schema:Person
79 N9226bddf2f824abd9a8cf79a0eb429e0 schema:name SOUTHALL, NOEL TERRENCE
80 rdf:type schema:Person
81 N971d9679ca7441a28b206d9713068f8a rdf:first N2d14af3133484fbe8111e7e8f274d670
82 rdf:rest Nb3f9b49be0b54216a54491fd684c0c2c
83 N9d912d55807649d0ac1e34f5159e2a75 schema:name HUANG, WENWEI
84 rdf:type schema:Person
85 Nabe6f0e5659849a894e96dff72c611f6 rdf:first N9d912d55807649d0ac1e34f5159e2a75
86 rdf:rest N56bd42b5e9c24875a1e90ed47b230adb
87 Naeb87f6bc6bb4fe9ad932adce77d913f schema:name TANAKA, TAKESHI
88 rdf:type schema:Person
89 Nb3f9b49be0b54216a54491fd684c0c2c rdf:first N4ba5615d1bdf4861a432495f698ea6a4
90 rdf:rest N6c12c107c9774b7fad2006952860bb83
91 Nd6894054d3174591804d5ae79be4213b schema:name KIM, MYUNGHOON
92 rdf:type schema:Person
93 Nd956ca60c9ed4fbda6fb183706f41891 schema:name SUN, WEI
94 rdf:type schema:Person
95 Ne359bfd7fc3749bab51aa8b186567710 rdf:first N0effd3106e964fac89704f80ea331a15
96 rdf:rest N4cd31ba2ac0e4d4d8d95da1a93a3f3f1
97 Nea081f9977df41b0ac79e4fadb1387d8 schema:name MAGLE, Crystal Tobin
98 rdf:type schema:Person
99 Nfa75d46f36604ffdbb96d08c7302db79 schema:name MCKEW, JOHN C.
100 rdf:type schema:Person
101 anzsrc-for:3114 schema:inDefinedTermSet anzsrc-for:
102 rdf:type schema:DefinedTerm
103 sg:pub.10.1038/nature09099 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042393051
104 https://doi.org/10.1038/nature09099
105 rdf:type schema:CreativeWork
106 sg:pub.10.1038/nchembio.215 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009958901
107 https://doi.org/10.1038/nchembio.215
108 rdf:type schema:CreativeWork
109 sg:pub.10.1038/nchembio.70 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044068305
110 https://doi.org/10.1038/nchembio.70
111 rdf:type schema:CreativeWork
112 https://doi.org/10.1016/0166-6851(82)90035-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020417610
113 rdf:type schema:CreativeWork
114 https://doi.org/10.1016/j.molbiopara.2013.02.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028431117
115 rdf:type schema:CreativeWork
116 https://doi.org/10.1021/jm101144f schema:sameAs https://app.dimensions.ai/details/publication/pub.1055951937
117 rdf:type schema:CreativeWork
118 https://doi.org/10.1021/jm101520v schema:sameAs https://app.dimensions.ai/details/publication/pub.1055952094
119 rdf:type schema:CreativeWork
120 https://doi.org/10.1073/pnas.0702136104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019440020
121 rdf:type schema:CreativeWork
122 https://doi.org/10.1073/pnas.0802982105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026974218
123 rdf:type schema:CreativeWork
124 https://doi.org/10.1073/pnas.0910040106 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003648417
125 rdf:type schema:CreativeWork
126 https://doi.org/10.1086/503051 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015282842
127 rdf:type schema:CreativeWork
128 https://doi.org/10.1086/644645 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009646480
129 rdf:type schema:CreativeWork
130 https://doi.org/10.1093/infdis/jir037 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052025999
131 rdf:type schema:CreativeWork
132 https://doi.org/10.1126/science.1205216 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062464676
133 rdf:type schema:CreativeWork
134 https://doi.org/10.1158/0008-5472.can-07-5256 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053497663
135 rdf:type schema:CreativeWork
136 https://doi.org/10.1158/0008-5472.can-09-3360 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019637270
137 rdf:type schema:CreativeWork
138 https://doi.org/10.1158/0008-5472.can-12-1702 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026359958
139 rdf:type schema:CreativeWork
140 https://doi.org/10.1158/1078-0432.ccr-10-1927 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052694111
141 rdf:type schema:CreativeWork
142 https://doi.org/10.1177/1087057112458152 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003386316
143 rdf:type schema:CreativeWork
144 https://www.grid.ac/institutes/grid.164971.c schema:Organization
 




Preview window. Press ESC to close (or click here)


...