Immunotherapeutic Potential Of Modified Lipooligosaccharides/Lipid A


Ontology type: sgo:Patent     


Patent Info

DATE

2014-09-12T00:00

AUTHORS

ERNST ROBERT K , PELLETIER MARK , HAJJAR ADELINE

ABSTRACT

Embodiments of the disclosure provide for unique lipooligosaccharide/lipid A-based mimetics for use as adjuvants. Methods of generating lipooligosaccharide/lipid A-based mimetics are provided that utilize recombinantly engineered bacteria to produce the mimetics, including, for example, addition of one or more particular enzymes such as acyltransferases, deacylases, phosphatases, or glycosyltransferases.

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