Variants Of Glycerol Dehydrogenase Having D-Lactate Dehydrogenase Activity And Uses Thereof


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

WANG, QINGZHAO , SHANMUGAM, KEELNATHAM, T. , INGRAM, LONNIE, O'NEAL

ABSTRACT

The present invention provides methods of designing and generating glycerol dehydrogenase (GlyDH) variants that have altered function as compared to a parent polypeptide. The present invention further provides nucleic acids encoding GlyDH polypeptide variants having altered function as compared to the parent polypeptide. Host cells comprising polynucleotides encoding GlyDH variants and methods of producing lactic acids are also provided in various aspects of the invention. More... »

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