2012-10-18T00:00
AUTHORSTJWA MARC
ABSTRACTThe present application relates to the field of microRNAs, and more particular to the role of microRNAs in angiogenesis. It is demonstrated herein that modulation of specific microRNAs, such as miR-144, has therapeutic potential in diseases characterized by aberrant angiogenesis. This is particularly relevant in, for instance, tumour growth and metastasis, which are characterized by excessive angiogenesis and for which inhibition of miR-144 is a novel therapeutic strategy. On the other hand, diseases characterized by insufficient angiogenesis (e.g. associated with ischemia) may benefit from increasing miR-144 activity. More... »
JSON-LD is the canonical representation for SciGraph data.
TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT
[
{
"@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json",
"about": [
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/06",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"type": "DefinedTerm"
},
{
"id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/0601",
"inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/",
"type": "DefinedTerm"
}
],
"author": [
{
"name": "TJWA MARC",
"type": "Person"
}
],
"citation": [
{
"id": "sg:pub.10.1038/5007",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1030839891",
"https://doi.org/10.1038/5007"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nm1428",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1015883708",
"https://doi.org/10.1038/nm1428"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature05355",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1037678066",
"https://doi.org/10.1038/nature05355"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature03080",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1031468029",
"https://doi.org/10.1038/nature03080"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature04478",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1011948458",
"https://doi.org/10.1038/nature04478"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nm988",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1003700365",
"https://doi.org/10.1038/nm988"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ng1744",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1047510709",
"https://doi.org/10.1038/ng1744"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/ncb1695",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1033239493",
"https://doi.org/10.1038/ncb1695"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature09092",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1018277529",
"https://doi.org/10.1038/nature09092"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nm0603-653",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1010143012",
"https://doi.org/10.1038/nm0603-653"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature04303",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1045870087",
"https://doi.org/10.1038/nature04303"
],
"type": "CreativeWork"
},
{
"id": "sg:pub.10.1038/nature05571",
"sameAs": [
"https://app.dimensions.ai/details/publication/pub.1009360999",
"https://doi.org/10.1038/nature05571"
],
"type": "CreativeWork"
}
],
"datePublished": "2012-10-18T00:00",
"description": "The present application relates to the field of microRNAs, and more particular to the role of microRNAs in angiogenesis. It is demonstrated herein that modulation of specific microRNAs, such as miR-144, has therapeutic potential in diseases characterized by aberrant angiogenesis. This is particularly relevant in, for instance, tumour growth and metastasis, which are characterized by excessive angiogenesis and for which inhibition of miR-144 is a novel therapeutic strategy. On the other hand, diseases characterized by insufficient angiogenesis (e.g. associated with ischemia) may benefit from increasing miR-144 activity.
",
"id": "sg:patent.WO-2012140234-A1",
"name": "MODULATION OF MIRNA IN DISEASES WITH ABERRANT ANGIOGENESIS",
"recipient": [
{
"id": "http://www.grid.ac/institutes/grid.11486.3a",
"type": "Organization"
}
],
"sameAs": [
"https://app.dimensions.ai/details/patent/WO-2012140234-A1"
],
"sdDataset": "patents",
"sdDatePublished": "2022-08-04T17:25",
"sdLicense": "https://scigraph.springernature.com/explorer/license/",
"sdPublisher": {
"name": "Springer Nature - SN SciGraph project",
"type": "Organization"
},
"sdSource": "s3://com-springernature-scigraph/baseset/20220804/entities/gbq_results/patent/patent_34.jsonl",
"type": "Patent"
}
]
Download the RDF metadata as: json-ld nt turtle xml License info
JSON-LD is a popular format for linked data which is fully compatible with JSON.
curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/patent.WO-2012140234-A1'
N-Triples is a line-based linked data format ideal for batch operations.
curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/patent.WO-2012140234-A1'
Turtle is a human-readable linked data format.
curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/patent.WO-2012140234-A1'
RDF/XML is a standard XML format for linked data.
curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/patent.WO-2012140234-A1'
This table displays all metadata directly associated to this object as RDF triples.
73 TRIPLES
14 PREDICATES
27 URIs
8 LITERALS
2 BLANK NODES