Novel Neural Progenitors From Pluripotent Stem Cells, Methods Of Producing Same And Use To Produce Neural Cells


Ontology type: sgo:Patent     


Patent Info

DATE

2011-03-31T00:00

AUTHORS

REYNOLDS, DAVID , SCHULZ, THOMAS , ROBINS, ALLAN , DALTON, STEPHEN

ABSTRACT

The present invention relates to the discovery of a novel multipotent stem cell termed pre-rosette stage ectoderm progenitor cells or BSC cells. These cells may be isolated, grown stably for a number of which are novel, self-renewing early ectodermal cell types (pre-rosette stage ectoderm progenitors) exhibiting neural progenitor-like characteristics generations and cryopreserved for stable storage. These cells may be further differentiated into neural cells such as neurons and glia cells, which may be used for transplantation and other therapies. Methods of producing these cells from pluripotent stem cells, including human embryonic stem cells, umbilical/placental blood cord stem cells or induced pluripotent stem cells (iPS cells or iPSCs), including reprogrammed adult progenitor cells, are also disclosed. More... »

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