Method For Producing A Nucleoprotein Nanoparticle


Ontology type: sgo:Patent     


Patent Info

DATE

2010-04-08T00:00

AUTHORS

ДОРОХОВ, Юрий Леонидович , УРЫВАЕВ, Леонид Викторович , ФРОЛОВА, Ольга Юрьевна , КОМАРОВА, Татьяна Валерьевна , ПЕТРУНЯ, Игорь Валерьевич , АЛЬХОВСКИЙ, Сергей Владимирович , САМОХВАЛОВ, Евгений Иванович

ABSTRACT

The invention relates to nanotechnology, biotechnology, genetic engineering and medicine and makes it possible to produce nucleoprotein nanostructures which exhibit various properties useful for health care purposes. The invention offers a new method for producing nucleoprotein nanoparticles, which involves (a) providing an expression vector for directing nucleic acid synthesis in a plant cell; (b) providing at least one expression vector for directing the synthesis of a protein in a plant cell, which is capable of binding with nucleic acid and forming nanoparticles; (c) introducing said vectors into the plant cell; and (d) cultivating the plant cell in conditions that provide for the combined expression of said vectors in the cell and the assembly of a nucleoprotein nanoparticle. Nanoparticles produced according to this method are also disclosed. The invention makes it possible to produce nucleoprotein nanoparticles based on virions, pseudoverions or virus-like particles. The nanoparticles produced can also contain a functional section in the form of an antigen or a sequence that binds and inactivates a pathogen. More... »

Related SciGraph Publications

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/3021", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/2447", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "name": "\u0414\u041e\u0420\u041e\u0425\u041e\u0412, \u042e\u0440\u0438\u0439 \u041b\u0435\u043e\u043d\u0438\u0434\u043e\u0432\u0438\u0447", 
        "type": "Person"
      }, 
      {
        "name": "\u0423\u0420\u042b\u0412\u0410\u0415\u0412, \u041b\u0435\u043e\u043d\u0438\u0434 \u0412\u0438\u043a\u0442\u043e\u0440\u043e\u0432\u0438\u0447", 
        "type": "Person"
      }, 
      {
        "name": "\u0424\u0420\u041e\u041b\u041e\u0412\u0410, \u041e\u043b\u044c\u0433\u0430 \u042e\u0440\u044c\u0435\u0432\u043d\u0430", 
        "type": "Person"
      }, 
      {
        "name": "\u041a\u041e\u041c\u0410\u0420\u041e\u0412\u0410, \u0422\u0430\u0442\u044c\u044f\u043d\u0430 \u0412\u0430\u043b\u0435\u0440\u044c\u0435\u0432\u043d\u0430", 
        "type": "Person"
      }, 
      {
        "name": "\u041f\u0415\u0422\u0420\u0423\u041d\u042f, \u0418\u0433\u043e\u0440\u044c \u0412\u0430\u043b\u0435\u0440\u044c\u0435\u0432\u0438\u0447", 
        "type": "Person"
      }, 
      {
        "name": "\u0410\u041b\u042c\u0425\u041e\u0412\u0421\u041a\u0418\u0419, \u0421\u0435\u0440\u0433\u0435\u0439 \u0412\u043b\u0430\u0434\u0438\u043c\u0438\u0440\u043e\u0432\u0438\u0447", 
        "type": "Person"
      }, 
      {
        "name": "\u0421\u0410\u041c\u041e\u0425\u0412\u0410\u041b\u041e\u0412, \u0415\u0432\u0433\u0435\u043d\u0438\u0439 \u0418\u0432\u0430\u043d\u043e\u0432\u0438\u0447", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1073/pnas.0608869103", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010485817"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nbt0195-53", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020590506", 
          "https://doi.org/10.1038/nbt0195-53"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0400149101", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033371390"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2010-04-08T00:00", 
    "description": "

The invention relates to nanotechnology, biotechnology, genetic engineering and medicine and makes it possible to produce nucleoprotein nanostructures which exhibit various properties useful for health care purposes. The invention offers a new method for producing nucleoprotein nanoparticles, which involves (a) providing an expression vector for directing nucleic acid synthesis in a plant cell; (b) providing at least one expression vector for directing the synthesis of a protein in a plant cell, which is capable of binding with nucleic acid and forming nanoparticles; (c) introducing said vectors into the plant cell; and (d) cultivating the plant cell in conditions that provide for the combined expression of said vectors in the cell and the assembly of a nucleoprotein nanoparticle. Nanoparticles produced according to this method are also disclosed. The invention makes it possible to produce nucleoprotein nanoparticles based on virions, pseudoverions or virus-like particles. The nanoparticles produced can also contain a functional section in the form of an antigen or a sequence that binds and inactivates a pathogen.

", "id": "sg:patent.WO-2010039056-A1", "keywords": [ "nucleoprotein", "invention", "nanotechnology", "biotechnology", "medicine", "health", "method", "expression vector", "nucleic acid synthesis", "plant cell", "synthesis", "protein", "binding", "nucleic acid", "nanoparticles", "vector", "condition", "expression", "cell", "assembly", "virion", "virus-like particle", "section", "antigen", "sequence", "pathogen" ], "name": "METHOD FOR PRODUCING A NUCLEOPROTEIN NANOPARTICLE", "sameAs": [ "https://app.dimensions.ai/details/patent/WO-2010039056-A1" ], "sdDataset": "patents", "sdDatePublished": "2019-04-18T10:05", "sdLicense": "https://scigraph.springernature.com/explorer/license/", "sdPublisher": { "name": "Springer Nature - SN SciGraph project", "type": "Organization" }, "sdSource": "s3://com-uberresearch-data-patents-target-20190320-rc/data/sn-export/402f166718b70575fb5d4ffe01f064d1/0000100128-0000352499/json_export_00044.jsonl", "type": "Patent" } ]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/patent.WO-2010039056-A1'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/patent.WO-2010039056-A1'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/patent.WO-2010039056-A1'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/patent.WO-2010039056-A1'


 

This table displays all metadata directly associated to this object as RDF triples.

83 TRIPLES      14 PREDICATES      43 URIs      34 LITERALS      2 BLANK NODES

Subject Predicate Object
1 sg:patent.WO-2010039056-A1 schema:about anzsrc-for:2447
2 anzsrc-for:3021
3 schema:author N0e2626fce70944b29efd436ced65cd1b
4 schema:citation sg:pub.10.1038/nbt0195-53
5 https://doi.org/10.1073/pnas.0400149101
6 https://doi.org/10.1073/pnas.0608869103
7 schema:datePublished 2010-04-08T00:00
8 schema:description <p>The invention relates to nanotechnology, biotechnology, genetic engineering and medicine and makes it possible to produce nucleoprotein nanostructures which exhibit various properties useful for health care purposes. The invention offers a new method for producing nucleoprotein nanoparticles, which involves (a) providing an expression vector for directing nucleic acid synthesis in a plant cell; (b) providing at least one expression vector for directing the synthesis of a protein in a plant cell, which is capable of binding with nucleic acid and forming nanoparticles; (c) introducing said vectors into the plant cell; and (d) cultivating the plant cell in conditions that provide for the combined expression of said vectors in the cell and the assembly of a nucleoprotein nanoparticle. Nanoparticles produced according to this method are also disclosed. The invention makes it possible to produce nucleoprotein nanoparticles based on virions, pseudoverions or virus-like particles. The nanoparticles produced can also contain a functional section in the form of an antigen or a sequence that binds and inactivates a pathogen.</p>
9 schema:keywords antigen
10 assembly
11 binding
12 biotechnology
13 cell
14 condition
15 expression
16 expression vector
17 health
18 invention
19 medicine
20 method
21 nanoparticles
22 nanotechnology
23 nucleic acid
24 nucleic acid synthesis
25 nucleoprotein
26 pathogen
27 plant cell
28 protein
29 section
30 sequence
31 synthesis
32 vector
33 virion
34 virus-like particle
35 schema:name METHOD FOR PRODUCING A NUCLEOPROTEIN NANOPARTICLE
36 schema:sameAs https://app.dimensions.ai/details/patent/WO-2010039056-A1
37 schema:sdDatePublished 2019-04-18T10:05
38 schema:sdLicense https://scigraph.springernature.com/explorer/license/
39 schema:sdPublisher Nfb7bdde7343f4cd0aed1267c98dd225f
40 sgo:license sg:explorer/license/
41 sgo:sdDataset patents
42 rdf:type sgo:Patent
43 N021adff528c543b5b14b7c30ce5a1098 schema:name САМОХВАЛОВ, Евгений Иванович
44 rdf:type schema:Person
45 N0e2626fce70944b29efd436ced65cd1b rdf:first N2df97562a75741399a561682966f160c
46 rdf:rest Nb1a4cb45fe8d475c860b52bd64099372
47 N10db3dd648114bd7aa3fce56c84bc216 rdf:first Nc9caa90ae4a944369ec715b79b70a8cd
48 rdf:rest Nb2f356258ead4dad82264a44ceb03d3f
49 N19498fe46ae94caea4deed4f350c1756 rdf:first Nd831daeacb684ab9a211a60ab0b3cb29
50 rdf:rest N10db3dd648114bd7aa3fce56c84bc216
51 N2df97562a75741399a561682966f160c schema:name ДОРОХОВ, Юрий Леонидович
52 rdf:type schema:Person
53 N596cf44ae09b4ae89ab74763cf4262cf rdf:first Nebb77d6c523b4866baeb2f6eee535647
54 rdf:rest N94ed5c819c914b679c236b01db588267
55 N8b611b7a7d4140028f679881833ceb3f schema:name КОМАРОВА, Татьяна Валерьевна
56 rdf:type schema:Person
57 N94ed5c819c914b679c236b01db588267 rdf:first N8b611b7a7d4140028f679881833ceb3f
58 rdf:rest N19498fe46ae94caea4deed4f350c1756
59 Nb1a4cb45fe8d475c860b52bd64099372 rdf:first Nc636f583d0b744cfb917b0901ec6b153
60 rdf:rest N596cf44ae09b4ae89ab74763cf4262cf
61 Nb2f356258ead4dad82264a44ceb03d3f rdf:first N021adff528c543b5b14b7c30ce5a1098
62 rdf:rest rdf:nil
63 Nc636f583d0b744cfb917b0901ec6b153 schema:name УРЫВАЕВ, Леонид Викторович
64 rdf:type schema:Person
65 Nc9caa90ae4a944369ec715b79b70a8cd schema:name АЛЬХОВСКИЙ, Сергей Владимирович
66 rdf:type schema:Person
67 Nd831daeacb684ab9a211a60ab0b3cb29 schema:name ПЕТРУНЯ, Игорь Валерьевич
68 rdf:type schema:Person
69 Nebb77d6c523b4866baeb2f6eee535647 schema:name ФРОЛОВА, Ольга Юрьевна
70 rdf:type schema:Person
71 Nfb7bdde7343f4cd0aed1267c98dd225f schema:name Springer Nature - SN SciGraph project
72 rdf:type schema:Organization
73 anzsrc-for:2447 schema:inDefinedTermSet anzsrc-for:
74 rdf:type schema:DefinedTerm
75 anzsrc-for:3021 schema:inDefinedTermSet anzsrc-for:
76 rdf:type schema:DefinedTerm
77 sg:pub.10.1038/nbt0195-53 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020590506
78 https://doi.org/10.1038/nbt0195-53
79 rdf:type schema:CreativeWork
80 https://doi.org/10.1073/pnas.0400149101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033371390
81 rdf:type schema:CreativeWork
82 https://doi.org/10.1073/pnas.0608869103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010485817
83 rdf:type schema:CreativeWork
 




Preview window. Press ESC to close (or click here)


...