Hybridization-Stabilizing Construct


Ontology type: sgo:Patent     


Patent Info

DATE

2006-12-28T00:00

AUTHORS

SMITH, EDVARD , SVAHN, MATHIAS , GE, RONGBIN

ABSTRACT

A Z-shaped construct having the capacity to hybridize to double stranded DNA in a trans fashion to affect transcription is produced from at least two oligonucleotides, connected to each other, wherein the oligonucleotides are connected to one another through one of sequence specific Watson-Crick base pairing; a covalent linker or a covalent bond directly between the backbones or the bases of said oligonucleotides; or a non-covalent linker or a non-covalent bond directly between the backbones or the bases of said oligonucleotides. More... »

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