Alpha-Difluoromethylornithine (Dfmo) Use In The Human Prostate


Ontology type: sgo:Patent     


Patent Info

DATE

2002-02-28T00:00

AUTHORS

MEYSKENS, FRANK, L., JR. , SIMONEAU, ANNE, R. , GERNER, EUGENE, W.

ABSTRACT

The present invention concerns a method for treating and/or inhibiting prostate cancer in a patient comprising administering α-difluoromethylornithine (DFMO) in an amount and duration sufficient to stabilize or reduce the amount of polyamine produced by the hyperplastic cells, wherein said polyamine is spermine, spermidine or a combination of spermine and spermidine. Methods of administration, dosing, and combinational therapies are described. More... »

Related SciGraph Publications

  • 2000-12. Polyamine depletion therapy in prostate cancer in PROSTATE CANCER AND PROSTATIC DISEASES
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