Methods And Apparatus For High-Throughput Detection And Characterization Of Alternatively Spliced Genes


Ontology type: sgo:Patent     


Patent Info

DATE

2001-08-09T00:00

AUTHORS

PENN, SHARRON, GAYNOR , RANK, DAVID, RUSSELL , HANZEL, DAVID, KAGEN

ABSTRACT

Methods and apparatus for designing and producing single exon probes from genomic sequence data are presented. Also presented are genome-derived single exon microarrays. The single exon probes and genome-derived microarrays are used for high throughput interrogation of exon-specific expression in a plurality of tissues and cell types. Alternative splice events are detected as reproducible changes in relative or absolute expression of exons. Visual tools and automated methods for detecting and characterizing the alternative splice events are presented. More... »

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