Methods For Making Proteins Containing Free Cysteine Residues


Ontology type: sgo:Patent     


Patent Info

DATE

2000-07-20T00:00

AUTHORS

COX, GEORGE, N. , DOHERTY, DANIEL, H. , ROSENDAHL, MARY, S.

ABSTRACT

The present invention relates to novel methods of making soluble proteins having free cysteines in which a host cell is exposed to a cysteine blocking agent. The soluble proteins produced by the methods can then be modified to increase their effectiveness. Such modifications include attaching a PEG moiety to form pegylated proteins. More... »

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