Cellular Vesicle Called ''Exosome'', Preparation And Use Thereof In Immune Stimulation


Ontology type: sgo:Patent     


Patent Info

DATE

1999-01-28T00:00

AUTHORS

ZITVOGEL, LAURENCE , RAPOSO, Graça , REGNAULT, ARMELLE , AMIGORENA, SEBASTIAN

ABSTRACT

The invention concerns a novel method for sensitising antigen-presenting cells, novel means for implementing the method, and novel membrane vesicles with immunogenic properties. The invention concerns particularly texosomes (vesicles derived from tumour cells ) and dexosomes (vesicles derived from dendritic cells loaded with antigens or not), and their use for vectoring and presenting antigens in vitro or in vivo and methods or compositions for treating cancers, infectious, parasitic or autoimmune diseases in particular. More... »

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