Compounds And Methods For Site-Directed Mutations In Eukaryotic Cells


Ontology type: sgo:Patent     


Patent Info

DATE

1995-06-15T00:00

AUTHORS

KMIEC, ERIC, B.

ABSTRACT

The present invention concerns a polynucleotide having both ribonucleotides and deoxyribonucleotides in a first strand and solely deoxyribonucleotides in a second strand; wherein the strands are Watson-Crick paired and are linked by an oligonucleotide so that the polynucleotide has at most a single 3' and a single 5' end. These ends can be ligated so that the polynucleotide is a single continuous circular polymer. The polynucleotide can be used to induce specific alterations in targeted genes. More... »

Related SciGraph Publications

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/2620", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "name": "KMIEC, ERIC, B.", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/344170a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022686577", 
          "https://doi.org/10.1038/344170a0"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "1995-06-15T00:00", 
    "description": "

The present invention concerns a polynucleotide having both ribonucleotides and deoxyribonucleotides in a first strand and solely deoxyribonucleotides in a second strand; wherein the strands are Watson-Crick paired and are linked by an oligonucleotide so that the polynucleotide has at most a single 3' and a single 5' end. These ends can be ligated so that the polynucleotide is a single continuous circular polymer. The polynucleotide can be used to induce specific alterations in targeted genes.

", "id": "sg:patent.WO-1995015972-A1", "keywords": [ "site-directed mutation", "invention", "polynucleotides", "ribonucleotides", "deoxyribonucleotides", "first strand", "second strand", "wherein", "strand", "Watson", "oligonucleotides", "polymer", "specific alteration", "targeted gene" ], "name": "COMPOUNDS AND METHODS FOR SITE-DIRECTED MUTATIONS IN EUKARYOTIC CELLS", "recipient": [ { "id": "https://www.grid.ac/institutes/grid.265008.9", "type": "Organization" } ], "sameAs": [ "https://app.dimensions.ai/details/patent/WO-1995015972-A1" ], "sdDataset": "patents", "sdDatePublished": "2019-04-18T10:30", "sdLicense": "https://scigraph.springernature.com/explorer/license/", "sdPublisher": { "name": "Springer Nature - SN SciGraph project", "type": "Organization" }, "sdSource": "s3://com-uberresearch-data-patents-target-20190320-rc/data/sn-export/402f166718b70575fb5d4ffe01f064d1/0000100128-0000352499/json_export_03421.jsonl", "type": "Patent" } ]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/patent.WO-1995015972-A1'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/patent.WO-1995015972-A1'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/patent.WO-1995015972-A1'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/patent.WO-1995015972-A1'


 

This table displays all metadata directly associated to this object as RDF triples.

40 TRIPLES      15 PREDICATES      29 URIs      22 LITERALS      2 BLANK NODES

Subject Predicate Object
1 sg:patent.WO-1995015972-A1 schema:about anzsrc-for:2620
2 schema:author Ndf2b8aa2e649413cb678666431cd5eb6
3 schema:citation sg:pub.10.1038/344170a0
4 schema:datePublished 1995-06-15T00:00
5 schema:description <p>The present invention concerns a polynucleotide having both ribonucleotides and deoxyribonucleotides in a first strand and solely deoxyribonucleotides in a second strand; wherein the strands are Watson-Crick paired and are linked by an oligonucleotide so that the polynucleotide has at most a single 3' and a single 5' end. These ends can be ligated so that the polynucleotide is a single continuous circular polymer. The polynucleotide can be used to induce specific alterations in targeted genes.</p>
6 schema:keywords Watson
7 deoxyribonucleotides
8 first strand
9 invention
10 oligonucleotides
11 polymer
12 polynucleotides
13 ribonucleotides
14 second strand
15 site-directed mutation
16 specific alteration
17 strand
18 targeted gene
19 wherein
20 schema:name COMPOUNDS AND METHODS FOR SITE-DIRECTED MUTATIONS IN EUKARYOTIC CELLS
21 schema:recipient https://www.grid.ac/institutes/grid.265008.9
22 schema:sameAs https://app.dimensions.ai/details/patent/WO-1995015972-A1
23 schema:sdDatePublished 2019-04-18T10:30
24 schema:sdLicense https://scigraph.springernature.com/explorer/license/
25 schema:sdPublisher N52313645a40a4dc68210a7e83aebb8ab
26 sgo:license sg:explorer/license/
27 sgo:sdDataset patents
28 rdf:type sgo:Patent
29 N52313645a40a4dc68210a7e83aebb8ab schema:name Springer Nature - SN SciGraph project
30 rdf:type schema:Organization
31 Naf02c55fd9744e79ade22e2df39dc458 schema:name KMIEC, ERIC, B.
32 rdf:type schema:Person
33 Ndf2b8aa2e649413cb678666431cd5eb6 rdf:first Naf02c55fd9744e79ade22e2df39dc458
34 rdf:rest rdf:nil
35 anzsrc-for:2620 schema:inDefinedTermSet anzsrc-for:
36 rdf:type schema:DefinedTerm
37 sg:pub.10.1038/344170a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022686577
38 https://doi.org/10.1038/344170a0
39 rdf:type schema:CreativeWork
40 https://www.grid.ac/institutes/grid.265008.9 schema:Organization
 




Preview window. Press ESC to close (or click here)


...