Devices and method for enrichment and alteration of cells and other particles


Ontology type: sgo:Patent     


Patent Info

DATE

2018-05-01T00:00

AUTHORS

Lotien Richard Huang , Thomas A. Barber , Bruce L. Carvalho , Ravi Kapur , Paul Vernucci , Mehmet Toner , Zihua Wang

ABSTRACT

The invention features devices and methods for the deterministic separation of particles. Exemplary methods include the enrichment of a sample in a desired particle or the alteration of a desired particle in the device. The devices and methods are advantageously employed to enrich for rare cells, e.g., fetal cells, present in a sample, e.g., maternal blood and rare cell components, e.g., fetal cell nuclei. The invention further provides a method for preferentially lysing cells of interest in a sample, e.g., to extract clinical information from a cellular component, e.g., a nucleus, of the cells of interest. In general, the method employs differential lysis between the cells of interest and other cells (e.g., other nucleated cells) in the sample. More... »

Related SciGraph Publications

  • 1989-05. Demonstration of spontaneous XX/XY chimerism by DNA fingerprinting in HUMAN GENETICS
  • 1986-12. Detection of chromosome aberrations in the human interphase nucleus by visualization of specific target DNAs with radioactive and non-radioactive in situ hybridization techniques: diagnosis of trisomy 18 with probe L1.84 in HUMAN GENETICS
  • 1995-08. Polymer microstructures formed by moulding in capillaries in NATURE
  • 1988-09. Amplification and analysis of DNA sequences in single human sperm and diploid cells in NATURE
  • 1988-11. Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries in HUMAN GENETICS
  • 1988-11. Detection of chromosome aberrations in metaphase and interphase tumor cells by in situ hybridization using chromosome-specific library probes in HUMAN GENETICS
  • 1999-11. A microfabricated fluorescence-activated cell sorter in NATURE BIOTECHNOLOGY
  • 2000-04. Functional hydrogel structures for autonomous flow control inside microfluidic channels in NATURE
  • 1987-03. DNA microextraction from dried blood spots on filter paper blotters: potential applications to newborn screening in HUMAN GENETICS
  • 1996-11. Prenatal diagnosis of sickle cell anaemia and thalassaemia by analysis of fetal cells in maternal blood in NATURE GENETICS
  • 2001-05. A rapid diffusion immunoassay in a T-sensor in NATURE BIOTECHNOLOGY
  • 1986-04. Hematological Values of 163 Normal Fetuses between 18 and 30 Weeks of Gestation in PEDIATRIC RESEARCH
  • 1992-08. DNA electrophoresis in microlithographic arrays in NATURE
  • 1987-05. Identification of extra-villous trophoblast cells in human decidua using an apparently unique murine monoclonal antibody to trophoblast in JOURNAL OF MOLECULAR HISTOLOGY
  • 1982-12. Fetal cells in the maternal circulation: Detection by direct AFP-immunofluorescence in HUMAN GENETICS
  • 2002-10. A DNA prism for high-speed continuous fractionation of large DNA molecules in NATURE BIOTECHNOLOGY
  • JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/3158", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "name": "Lotien Richard Huang", 
            "type": "Person"
          }, 
          {
            "name": "Thomas A. Barber", 
            "type": "Person"
          }, 
          {
            "name": "Bruce L. Carvalho", 
            "type": "Person"
          }, 
          {
            "name": "Ravi Kapur", 
            "type": "Person"
          }, 
          {
            "name": "Paul Vernucci", 
            "type": "Person"
          }, 
          {
            "name": "Mehmet Toner", 
            "type": "Person"
          }, 
          {
            "name": "Zihua Wang", 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1016/s0006-3495(96)79538-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000069098"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/pd.1970050602", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000272470"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/cyto.10112", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000677863"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0006-3495(95)80443-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001259652"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1084/jem.160.3.633", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002142674"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0022-1759(86)90096-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002238879"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0022-1759(86)90096-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002238879"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.0404036101", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002440023"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3109/00313028409067911", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002441520"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3109/00313028409067911", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002441520"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac990504j", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002677891"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac990504j", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002677891"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/mcp.m600246-mcp200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003502507"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1088/0960-1317/9/4/318", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003669344"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1399-0039.1980.tb00313.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003689159"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/pd.1970121015", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003816356"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.chroma.2007.06.025", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004050256"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0006-3495(03)75069-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004177051"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00333523", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004418641", 
              "https://doi.org/10.1007/bf00333523"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00333523", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004418641", 
              "https://doi.org/10.1007/bf00333523"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf01790091", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004492303", 
              "https://doi.org/10.1007/bf01790091"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf01790091", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004492303", 
              "https://doi.org/10.1007/bf01790091"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.87.9.3279", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004598196"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.96.10.5545", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004720306"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(89)91969-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005136045"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/(sici)1522-2683(19990701)20:9<1829::aid-elps1829>3.0.co;2-b", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006118318"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt733", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006242078", 
              "https://doi.org/10.1038/nbt733"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nbt733", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006242078", 
              "https://doi.org/10.1038/nbt733"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1056/nejmoa050995", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007158962"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/1522-2683(200110)22:18<3883::aid-elps3883>3.0.co;2-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007488830"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00280484", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007551618", 
              "https://doi.org/10.1007/bf00280484"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00280484", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007551618", 
              "https://doi.org/10.1007/bf00280484"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/(sici)1097-0223(199708)17:8<743::aid-pd144>3.0.co;2-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008098693"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.051631798", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008647723"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.humpath.2006.01.026", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008800830"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1006/bbrc.1999.0445", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008971522"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/la000600b", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008986356"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/la000600b", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008986356"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/nar/gkl740", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009210837"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/cyto.a.20369", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009489796"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0378-4347(98)00308-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009515152"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0006-3495(01)76035-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009663804"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.96.24.13762", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011096471"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0161-5890(83)90166-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011228677"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0161-5890(83)90166-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011228677"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0165-022x(98)00010-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011857171"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(89)91723-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012742575"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(89)91723-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012742575"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/pd.1970130306", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014031228"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1056/nejm198710153171603", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014157998"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/nar/14.3.1325", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014614266"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf01790090", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014889149", 
              "https://doi.org/10.1007/bf01790090"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf01790090", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014889149", 
              "https://doi.org/10.1007/bf01790090"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/nar/16.23.11141", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015096617"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(84)90182-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015306892"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(84)90182-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015306892"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1039/b400455h", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015749457"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.93.16.8508", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015938894"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/molehr/gag027", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016394926"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/pd.1970080806", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016777223"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0925-4005(94)01196-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018195365"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.78.5.3039", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018965657"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.78.8.5147", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019158190"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1056/nejm198809013190903", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019810917"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(84)90875-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020585609"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(84)90875-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020585609"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0002-9378(16)36649-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1020750575"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00284058", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021584148", 
              "https://doi.org/10.1007/bf00284058"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00284058", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021584148", 
              "https://doi.org/10.1007/bf00284058"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/cyto.990080213", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021783867"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/cyto.990080213", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021783867"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0002-9440(10)64348-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021815897"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/1522-2683(200207)23:13<1984::aid-elps1984>3.0.co;2-u", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022032964"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/pd.1970120104", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022551679"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/376581a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022935813", 
              "https://doi.org/10.1038/376581a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1088/0960-1317/4/4/003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023578349"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/88135", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024064207", 
              "https://doi.org/10.1038/88135"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/88135", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024064207", 
              "https://doi.org/10.1038/88135"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0140-6736(90)91731-o", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024572376"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0140-6736(90)91731-o", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024572376"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/pd.1970010111", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024685867"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.285.5424.83", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024794668"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(73)91675-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024882636"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(73)91675-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024882636"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35007047", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025343153", 
              "https://doi.org/10.1038/35007047"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/35007047", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025343153", 
              "https://doi.org/10.1038/35007047"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/(sici)1097-0223(199710)17:10<953::aid-pd182>3.0.co;2-e", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025460961"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/(sici)1097-0223(199710)17:10<953::aid-pd182>3.0.co;2-e", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025460961"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1088/0960-1317/4/4/001", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027147727"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.76.3.1453", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027184311"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(03)12798-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027518865"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0002-9440(10)64706-2", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028565116"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1034/j.1399-0004.2001.600209.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029889629"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1172/jci114188", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1030912262"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0002-9378(91)90024-l", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031030756"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.040562297", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031059605"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf01675689", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031401691", 
              "https://doi.org/10.1007/bf01675689"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf01675689", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031401691", 
              "https://doi.org/10.1007/bf01675689"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/pd.57", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031670133"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(88)91295-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032333211"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(88)91295-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032333211"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1056/nejm198503143121103", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032479478"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/bp0256216", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032632659"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1088/0960-1317/8/1/004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032633956"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.yexcr.2004.08.039", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034627415"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0167-9317(86)90004-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035144482"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0167-9317(86)90004-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035144482"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0022-1759(83)80016-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035718539"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/15095", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036226690", 
              "https://doi.org/10.1038/15095"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/15095", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036226690", 
              "https://doi.org/10.1038/15095"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/cncr.10776", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036315679"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/pd.1970080807", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037941080"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(89)90509-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038476984"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00281061", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038775598", 
              "https://doi.org/10.1007/bf00281061"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00281061", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038775598", 
              "https://doi.org/10.1007/bf00281061"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/335414a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038895472", 
              "https://doi.org/10.1038/335414a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/33.10.3900197", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039886282"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/33.10.3900197", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039886282"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1203/00006450-198604000-00017", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039912509", 
              "https://doi.org/10.1203/00006450-198604000-00017"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1146/annurev.bioeng.7.011205.135108", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039926044"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1172/jci113409", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040139164"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ng1196-264", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040414398", 
              "https://doi.org/10.1038/ng1196-264"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0924-4247(90)87066-r", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040479293"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/358600a0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041011884", 
              "https://doi.org/10.1038/358600a0"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.91.13.5740", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041174406"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.1094567", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042009152"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/mcb.2.5.578", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042392200"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0002-9378(92)91603-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043300168"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1136/jmg.12.3.230", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043539854"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0002-9378(99)70622-8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044544971"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1159/000082432", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045052290"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.canlet.2006.12.014", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045175509"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0192-0561(81)90022-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045258251"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0192-0561(81)90022-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045258251"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/pd.1970090508", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045465671"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.83.9.2934", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046429766"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0022-1759(89)90246-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046829294"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0022-1759(89)90246-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046829294"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1158/0008-5472.can-04-3196", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047207617"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0968-0004(82)90184-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047375567"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0968-0004(82)90184-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047375567"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1028-4559(09)60184-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047390250"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.96.1.11", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048334616"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00007890-198408000-00009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048888098"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/00007890-198408000-00009", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1048888098"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(69)91642-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049851111"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0140-6736(69)91642-0", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049851111"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/pd.1970110807", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051059133"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1471-0528.1995.tb09065.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051106449"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1471-0528.1995.tb09065.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051106449"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.85.23.9138", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053213537"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/ajmg.1350", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053693067"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac001109s", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1054972555"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac001109s", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1054972555"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac0255330", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1054994040"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac0255330", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1054994040"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac048196z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1054996007"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac048196z", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1054996007"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac049429p", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1054996554"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac049429p", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1054996554"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac058013o", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1054997945"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac058013o", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1054997945"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac950766v", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055072296"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac950766v", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055072296"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac9606564", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055072918"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac9606564", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055072918"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac971063b", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055074435"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ac971063b", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055074435"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1021/ja973071f", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1055868473"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1063/1.1356728", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1057698373"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1063/1.329003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1057931806"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1086/514885", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1058789371"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/hmg/1.5.307", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1059643892"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1101/sqb.1986.051.01.032", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060405782"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1103/physrevlett.79.2149", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060815844"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1103/physrevlett.79.2149", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060815844"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1103/physrevlett.80.1552", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060816922"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1103/physrevlett.80.1552", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060816922"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1103/physrevlett.88.128103", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060824650"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1103/physrevlett.88.128103", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1060824650"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1109/28.54263", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1061142682"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1109/77.828383", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1061226553"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1109/84.157362", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1061240456"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1109/84.285720", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1061240486"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1109/84.735347", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1061240655"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1109/84.982861", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1061240867"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1109/jmems.2003.818457", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1061289825"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1109/tnb.2004.837903", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1061713652"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1116/1.571222", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062181269"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.2416058", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062536806"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.276.5313.779", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062556573"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.283.5400.346", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062563859"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1126/science.288.5468.1026", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062569397"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/oxfordjournals.humrep.a137290", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1077464208"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2018-05-01T00:00", 
        "description": "

    The invention features devices and methods for the deterministic separation of particles. Exemplary methods include the enrichment of a sample in a desired particle or the alteration of a desired particle in the device. The devices and methods are advantageously employed to enrich for rare cells, e.g., fetal cells, present in a sample, e.g., maternal blood and rare cell components, e.g., fetal cell nuclei. The invention further provides a method for preferentially lysing cells of interest in a sample, e.g., to extract clinical information from a cellular component, e.g., a nucleus, of the cells of interest. In general, the method employs differential lysis between the cells of interest and other cells (e.g., other nucleated cells) in the sample.

    ", "id": "sg:patent.US-9956562-B2", "keywords": [ "Equipment and Supply", "method", "enrichment", "alteration", "cell", "particle", "invention", "sample", "rare cell", "fetal cell", "maternal blood", "cell nucleus", "clinical information", "cellular component", "nucleus", "lysis", "nucleated cell" ], "name": "Devices and method for enrichment and alteration of cells and other particles", "recipient": [ { "id": "https://www.grid.ac/institutes/grid.494219.3", "type": "Organization" }, { "id": "https://www.grid.ac/institutes/grid.32224.35", "type": "Organization" } ], "sameAs": [ "https://app.dimensions.ai/details/patent/US-9956562-B2" ], "sdDataset": "patents", "sdDatePublished": "2019-04-18T10:22", "sdLicense": "https://scigraph.springernature.com/explorer/license/", "sdPublisher": { "name": "Springer Nature - SN SciGraph project", "type": "Organization" }, "sdSource": "s3://com-uberresearch-data-patents-target-20190320-rc/data/sn-export/402f166718b70575fb5d4ffe01f064d1/0000100128-0000352499/json_export_01738.jsonl", "type": "Patent" } ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/patent.US-9956562-B2'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/patent.US-9956562-B2'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/patent.US-9956562-B2'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/patent.US-9956562-B2'


     

    This table displays all metadata directly associated to this object as RDF triples.

    534 TRIPLES      15 PREDICATES      183 URIs      25 LITERALS      2 BLANK NODES

    Subject Predicate Object
    1 sg:patent.US-9956562-B2 schema:about anzsrc-for:3158
    2 schema:author N5f34a905e3c74d9ba4274c38dcd9ee17
    3 schema:citation sg:pub.10.1007/bf00280484
    4 sg:pub.10.1007/bf00281061
    5 sg:pub.10.1007/bf00284058
    6 sg:pub.10.1007/bf00333523
    7 sg:pub.10.1007/bf01675689
    8 sg:pub.10.1007/bf01790090
    9 sg:pub.10.1007/bf01790091
    10 sg:pub.10.1038/15095
    11 sg:pub.10.1038/335414a0
    12 sg:pub.10.1038/35007047
    13 sg:pub.10.1038/358600a0
    14 sg:pub.10.1038/376581a0
    15 sg:pub.10.1038/88135
    16 sg:pub.10.1038/nbt733
    17 sg:pub.10.1038/ng1196-264
    18 sg:pub.10.1203/00006450-198604000-00017
    19 https://doi.org/10.1002/(sici)1097-0223(199708)17:8<743::aid-pd144>3.0.co;2-3
    20 https://doi.org/10.1002/(sici)1097-0223(199710)17:10<953::aid-pd182>3.0.co;2-e
    21 https://doi.org/10.1002/(sici)1522-2683(19990701)20:9<1829::aid-elps1829>3.0.co;2-b
    22 https://doi.org/10.1002/1522-2683(200110)22:18<3883::aid-elps3883>3.0.co;2-4
    23 https://doi.org/10.1002/1522-2683(200207)23:13<1984::aid-elps1984>3.0.co;2-u
    24 https://doi.org/10.1002/ajmg.1350
    25 https://doi.org/10.1002/cncr.10776
    26 https://doi.org/10.1002/cyto.10112
    27 https://doi.org/10.1002/cyto.990080213
    28 https://doi.org/10.1002/cyto.a.20369
    29 https://doi.org/10.1002/pd.1970010111
    30 https://doi.org/10.1002/pd.1970050602
    31 https://doi.org/10.1002/pd.1970080806
    32 https://doi.org/10.1002/pd.1970080807
    33 https://doi.org/10.1002/pd.1970090508
    34 https://doi.org/10.1002/pd.1970110807
    35 https://doi.org/10.1002/pd.1970120104
    36 https://doi.org/10.1002/pd.1970121015
    37 https://doi.org/10.1002/pd.1970130306
    38 https://doi.org/10.1002/pd.57
    39 https://doi.org/10.1006/bbrc.1999.0445
    40 https://doi.org/10.1016/0002-9378(91)90024-l
    41 https://doi.org/10.1016/0002-9378(92)91603-8
    42 https://doi.org/10.1016/0022-1759(86)90096-7
    43 https://doi.org/10.1016/0022-1759(89)90246-9
    44 https://doi.org/10.1016/0140-6736(90)91731-o
    45 https://doi.org/10.1016/0161-5890(83)90166-9
    46 https://doi.org/10.1016/0167-9317(86)90004-3
    47 https://doi.org/10.1016/0192-0561(81)90022-9
    48 https://doi.org/10.1016/0924-4247(90)87066-r
    49 https://doi.org/10.1016/0925-4005(94)01196-6
    50 https://doi.org/10.1016/0968-0004(82)90184-0
    51 https://doi.org/10.1016/j.canlet.2006.12.014
    52 https://doi.org/10.1016/j.chroma.2007.06.025
    53 https://doi.org/10.1016/j.humpath.2006.01.026
    54 https://doi.org/10.1016/j.yexcr.2004.08.039
    55 https://doi.org/10.1016/s0002-9378(16)36649-2
    56 https://doi.org/10.1016/s0002-9378(99)70622-8
    57 https://doi.org/10.1016/s0002-9440(10)64348-9
    58 https://doi.org/10.1016/s0002-9440(10)64706-2
    59 https://doi.org/10.1016/s0006-3495(01)76035-3
    60 https://doi.org/10.1016/s0006-3495(03)75069-3
    61 https://doi.org/10.1016/s0006-3495(95)80443-1
    62 https://doi.org/10.1016/s0006-3495(96)79538-3
    63 https://doi.org/10.1016/s0022-1759(83)80016-7
    64 https://doi.org/10.1016/s0140-6736(03)12798-5
    65 https://doi.org/10.1016/s0140-6736(69)91642-0
    66 https://doi.org/10.1016/s0140-6736(73)91675-9
    67 https://doi.org/10.1016/s0140-6736(84)90182-x
    68 https://doi.org/10.1016/s0140-6736(84)90875-4
    69 https://doi.org/10.1016/s0140-6736(88)91295-0
    70 https://doi.org/10.1016/s0140-6736(89)90509-6
    71 https://doi.org/10.1016/s0140-6736(89)91723-6
    72 https://doi.org/10.1016/s0140-6736(89)91969-7
    73 https://doi.org/10.1016/s0165-022x(98)00010-4
    74 https://doi.org/10.1016/s0378-4347(98)00308-9
    75 https://doi.org/10.1016/s1028-4559(09)60184-4
    76 https://doi.org/10.1021/ac001109s
    77 https://doi.org/10.1021/ac0255330
    78 https://doi.org/10.1021/ac048196z
    79 https://doi.org/10.1021/ac049429p
    80 https://doi.org/10.1021/ac058013o
    81 https://doi.org/10.1021/ac950766v
    82 https://doi.org/10.1021/ac9606564
    83 https://doi.org/10.1021/ac971063b
    84 https://doi.org/10.1021/ac990504j
    85 https://doi.org/10.1021/bp0256216
    86 https://doi.org/10.1021/ja973071f
    87 https://doi.org/10.1021/la000600b
    88 https://doi.org/10.1034/j.1399-0004.2001.600209.x
    89 https://doi.org/10.1039/b400455h
    90 https://doi.org/10.1056/nejm198503143121103
    91 https://doi.org/10.1056/nejm198710153171603
    92 https://doi.org/10.1056/nejm198809013190903
    93 https://doi.org/10.1056/nejmoa050995
    94 https://doi.org/10.1063/1.1356728
    95 https://doi.org/10.1063/1.329003
    96 https://doi.org/10.1073/pnas.0404036101
    97 https://doi.org/10.1073/pnas.040562297
    98 https://doi.org/10.1073/pnas.051631798
    99 https://doi.org/10.1073/pnas.76.3.1453
    100 https://doi.org/10.1073/pnas.78.5.3039
    101 https://doi.org/10.1073/pnas.78.8.5147
    102 https://doi.org/10.1073/pnas.83.9.2934
    103 https://doi.org/10.1073/pnas.85.23.9138
    104 https://doi.org/10.1073/pnas.87.9.3279
    105 https://doi.org/10.1073/pnas.91.13.5740
    106 https://doi.org/10.1073/pnas.93.16.8508
    107 https://doi.org/10.1073/pnas.96.1.11
    108 https://doi.org/10.1073/pnas.96.10.5545
    109 https://doi.org/10.1073/pnas.96.24.13762
    110 https://doi.org/10.1074/mcp.m600246-mcp200
    111 https://doi.org/10.1084/jem.160.3.633
    112 https://doi.org/10.1086/514885
    113 https://doi.org/10.1088/0960-1317/4/4/001
    114 https://doi.org/10.1088/0960-1317/4/4/003
    115 https://doi.org/10.1088/0960-1317/8/1/004
    116 https://doi.org/10.1088/0960-1317/9/4/318
    117 https://doi.org/10.1093/hmg/1.5.307
    118 https://doi.org/10.1093/molehr/gag027
    119 https://doi.org/10.1093/nar/14.3.1325
    120 https://doi.org/10.1093/nar/16.23.11141
    121 https://doi.org/10.1093/nar/gkl740
    122 https://doi.org/10.1093/oxfordjournals.humrep.a137290
    123 https://doi.org/10.1097/00007890-198408000-00009
    124 https://doi.org/10.1101/sqb.1986.051.01.032
    125 https://doi.org/10.1103/physrevlett.79.2149
    126 https://doi.org/10.1103/physrevlett.80.1552
    127 https://doi.org/10.1103/physrevlett.88.128103
    128 https://doi.org/10.1109/28.54263
    129 https://doi.org/10.1109/77.828383
    130 https://doi.org/10.1109/84.157362
    131 https://doi.org/10.1109/84.285720
    132 https://doi.org/10.1109/84.735347
    133 https://doi.org/10.1109/84.982861
    134 https://doi.org/10.1109/jmems.2003.818457
    135 https://doi.org/10.1109/tnb.2004.837903
    136 https://doi.org/10.1111/j.1399-0039.1980.tb00313.x
    137 https://doi.org/10.1111/j.1471-0528.1995.tb09065.x
    138 https://doi.org/10.1116/1.571222
    139 https://doi.org/10.1126/science.1094567
    140 https://doi.org/10.1126/science.2416058
    141 https://doi.org/10.1126/science.276.5313.779
    142 https://doi.org/10.1126/science.283.5400.346
    143 https://doi.org/10.1126/science.285.5424.83
    144 https://doi.org/10.1126/science.288.5468.1026
    145 https://doi.org/10.1128/mcb.2.5.578
    146 https://doi.org/10.1136/jmg.12.3.230
    147 https://doi.org/10.1146/annurev.bioeng.7.011205.135108
    148 https://doi.org/10.1158/0008-5472.can-04-3196
    149 https://doi.org/10.1159/000082432
    150 https://doi.org/10.1172/jci113409
    151 https://doi.org/10.1172/jci114188
    152 https://doi.org/10.1177/33.10.3900197
    153 https://doi.org/10.3109/00313028409067911
    154 schema:datePublished 2018-05-01T00:00
    155 schema:description <p id="p-0001" num="0000">The invention features devices and methods for the deterministic separation of particles. Exemplary methods include the enrichment of a sample in a desired particle or the alteration of a desired particle in the device. The devices and methods are advantageously employed to enrich for rare cells, e.g., fetal cells, present in a sample, e.g., maternal blood and rare cell components, e.g., fetal cell nuclei. The invention further provides a method for preferentially lysing cells of interest in a sample, e.g., to extract clinical information from a cellular component, e.g., a nucleus, of the cells of interest. In general, the method employs differential lysis between the cells of interest and other cells (e.g., other nucleated cells) in the sample.</p>
    156 schema:keywords Equipment and Supply
    157 alteration
    158 cell
    159 cell nucleus
    160 cellular component
    161 clinical information
    162 enrichment
    163 fetal cell
    164 invention
    165 lysis
    166 maternal blood
    167 method
    168 nucleated cell
    169 nucleus
    170 particle
    171 rare cell
    172 sample
    173 schema:name Devices and method for enrichment and alteration of cells and other particles
    174 schema:recipient https://www.grid.ac/institutes/grid.32224.35
    175 https://www.grid.ac/institutes/grid.494219.3
    176 schema:sameAs https://app.dimensions.ai/details/patent/US-9956562-B2
    177 schema:sdDatePublished 2019-04-18T10:22
    178 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    179 schema:sdPublisher N7725c040eb404597af61fdd46e98863c
    180 sgo:license sg:explorer/license/
    181 sgo:sdDataset patents
    182 rdf:type sgo:Patent
    183 N0112f76f7f014630bb55027bfe867a1d rdf:first N053264b3464f46939b9499e277d83843
    184 rdf:rest N9aac6f82477743c88ef2164d90f4254a
    185 N0221971f728541b5b9d4e4a1b777ffc1 schema:name Lotien Richard Huang
    186 rdf:type schema:Person
    187 N053264b3464f46939b9499e277d83843 schema:name Bruce L. Carvalho
    188 rdf:type schema:Person
    189 N58943e8fd3dd4e4a918678949f09fe0f schema:name Paul Vernucci
    190 rdf:type schema:Person
    191 N5f34a905e3c74d9ba4274c38dcd9ee17 rdf:first N0221971f728541b5b9d4e4a1b777ffc1
    192 rdf:rest N8d3c13d1588c44b3b1e2ee2181257ce2
    193 N7725c040eb404597af61fdd46e98863c schema:name Springer Nature - SN SciGraph project
    194 rdf:type schema:Organization
    195 N8d3c13d1588c44b3b1e2ee2181257ce2 rdf:first Na097bb8ab4294267af8dffb41745919b
    196 rdf:rest N0112f76f7f014630bb55027bfe867a1d
    197 N9aac6f82477743c88ef2164d90f4254a rdf:first Nca8201d0ca0f474faa4d5c19000d4181
    198 rdf:rest Na551575ef9894a80a673e8c7fe1484f6
    199 N9c8c8ace0b5e4a549ba91e43e42ea9ca rdf:first Nd1d82fab98824286979665fff2308ab3
    200 rdf:rest rdf:nil
    201 Na097bb8ab4294267af8dffb41745919b schema:name Thomas A. Barber
    202 rdf:type schema:Person
    203 Na551575ef9894a80a673e8c7fe1484f6 rdf:first N58943e8fd3dd4e4a918678949f09fe0f
    204 rdf:rest Nae2036ae35324a8fb1e00bbe451cb2c3
    205 Nae2036ae35324a8fb1e00bbe451cb2c3 rdf:first Nee41487f72e045bda13f1c6bf61f0235
    206 rdf:rest N9c8c8ace0b5e4a549ba91e43e42ea9ca
    207 Nca8201d0ca0f474faa4d5c19000d4181 schema:name Ravi Kapur
    208 rdf:type schema:Person
    209 Nd1d82fab98824286979665fff2308ab3 schema:name Zihua Wang
    210 rdf:type schema:Person
    211 Nee41487f72e045bda13f1c6bf61f0235 schema:name Mehmet Toner
    212 rdf:type schema:Person
    213 anzsrc-for:3158 schema:inDefinedTermSet anzsrc-for:
    214 rdf:type schema:DefinedTerm
    215 sg:pub.10.1007/bf00280484 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007551618
    216 https://doi.org/10.1007/bf00280484
    217 rdf:type schema:CreativeWork
    218 sg:pub.10.1007/bf00281061 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038775598
    219 https://doi.org/10.1007/bf00281061
    220 rdf:type schema:CreativeWork
    221 sg:pub.10.1007/bf00284058 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021584148
    222 https://doi.org/10.1007/bf00284058
    223 rdf:type schema:CreativeWork
    224 sg:pub.10.1007/bf00333523 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004418641
    225 https://doi.org/10.1007/bf00333523
    226 rdf:type schema:CreativeWork
    227 sg:pub.10.1007/bf01675689 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031401691
    228 https://doi.org/10.1007/bf01675689
    229 rdf:type schema:CreativeWork
    230 sg:pub.10.1007/bf01790090 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014889149
    231 https://doi.org/10.1007/bf01790090
    232 rdf:type schema:CreativeWork
    233 sg:pub.10.1007/bf01790091 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004492303
    234 https://doi.org/10.1007/bf01790091
    235 rdf:type schema:CreativeWork
    236 sg:pub.10.1038/15095 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036226690
    237 https://doi.org/10.1038/15095
    238 rdf:type schema:CreativeWork
    239 sg:pub.10.1038/335414a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038895472
    240 https://doi.org/10.1038/335414a0
    241 rdf:type schema:CreativeWork
    242 sg:pub.10.1038/35007047 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025343153
    243 https://doi.org/10.1038/35007047
    244 rdf:type schema:CreativeWork
    245 sg:pub.10.1038/358600a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041011884
    246 https://doi.org/10.1038/358600a0
    247 rdf:type schema:CreativeWork
    248 sg:pub.10.1038/376581a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022935813
    249 https://doi.org/10.1038/376581a0
    250 rdf:type schema:CreativeWork
    251 sg:pub.10.1038/88135 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024064207
    252 https://doi.org/10.1038/88135
    253 rdf:type schema:CreativeWork
    254 sg:pub.10.1038/nbt733 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006242078
    255 https://doi.org/10.1038/nbt733
    256 rdf:type schema:CreativeWork
    257 sg:pub.10.1038/ng1196-264 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040414398
    258 https://doi.org/10.1038/ng1196-264
    259 rdf:type schema:CreativeWork
    260 sg:pub.10.1203/00006450-198604000-00017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039912509
    261 https://doi.org/10.1203/00006450-198604000-00017
    262 rdf:type schema:CreativeWork
    263 https://doi.org/10.1002/(sici)1097-0223(199708)17:8<743::aid-pd144>3.0.co;2-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008098693
    264 rdf:type schema:CreativeWork
    265 https://doi.org/10.1002/(sici)1097-0223(199710)17:10<953::aid-pd182>3.0.co;2-e schema:sameAs https://app.dimensions.ai/details/publication/pub.1025460961
    266 rdf:type schema:CreativeWork
    267 https://doi.org/10.1002/(sici)1522-2683(19990701)20:9<1829::aid-elps1829>3.0.co;2-b schema:sameAs https://app.dimensions.ai/details/publication/pub.1006118318
    268 rdf:type schema:CreativeWork
    269 https://doi.org/10.1002/1522-2683(200110)22:18<3883::aid-elps3883>3.0.co;2-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007488830
    270 rdf:type schema:CreativeWork
    271 https://doi.org/10.1002/1522-2683(200207)23:13<1984::aid-elps1984>3.0.co;2-u schema:sameAs https://app.dimensions.ai/details/publication/pub.1022032964
    272 rdf:type schema:CreativeWork
    273 https://doi.org/10.1002/ajmg.1350 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053693067
    274 rdf:type schema:CreativeWork
    275 https://doi.org/10.1002/cncr.10776 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036315679
    276 rdf:type schema:CreativeWork
    277 https://doi.org/10.1002/cyto.10112 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000677863
    278 rdf:type schema:CreativeWork
    279 https://doi.org/10.1002/cyto.990080213 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021783867
    280 rdf:type schema:CreativeWork
    281 https://doi.org/10.1002/cyto.a.20369 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009489796
    282 rdf:type schema:CreativeWork
    283 https://doi.org/10.1002/pd.1970010111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024685867
    284 rdf:type schema:CreativeWork
    285 https://doi.org/10.1002/pd.1970050602 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000272470
    286 rdf:type schema:CreativeWork
    287 https://doi.org/10.1002/pd.1970080806 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016777223
    288 rdf:type schema:CreativeWork
    289 https://doi.org/10.1002/pd.1970080807 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037941080
    290 rdf:type schema:CreativeWork
    291 https://doi.org/10.1002/pd.1970090508 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045465671
    292 rdf:type schema:CreativeWork
    293 https://doi.org/10.1002/pd.1970110807 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051059133
    294 rdf:type schema:CreativeWork
    295 https://doi.org/10.1002/pd.1970120104 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022551679
    296 rdf:type schema:CreativeWork
    297 https://doi.org/10.1002/pd.1970121015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003816356
    298 rdf:type schema:CreativeWork
    299 https://doi.org/10.1002/pd.1970130306 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014031228
    300 rdf:type schema:CreativeWork
    301 https://doi.org/10.1002/pd.57 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031670133
    302 rdf:type schema:CreativeWork
    303 https://doi.org/10.1006/bbrc.1999.0445 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008971522
    304 rdf:type schema:CreativeWork
    305 https://doi.org/10.1016/0002-9378(91)90024-l schema:sameAs https://app.dimensions.ai/details/publication/pub.1031030756
    306 rdf:type schema:CreativeWork
    307 https://doi.org/10.1016/0002-9378(92)91603-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043300168
    308 rdf:type schema:CreativeWork
    309 https://doi.org/10.1016/0022-1759(86)90096-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002238879
    310 rdf:type schema:CreativeWork
    311 https://doi.org/10.1016/0022-1759(89)90246-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046829294
    312 rdf:type schema:CreativeWork
    313 https://doi.org/10.1016/0140-6736(90)91731-o schema:sameAs https://app.dimensions.ai/details/publication/pub.1024572376
    314 rdf:type schema:CreativeWork
    315 https://doi.org/10.1016/0161-5890(83)90166-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011228677
    316 rdf:type schema:CreativeWork
    317 https://doi.org/10.1016/0167-9317(86)90004-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035144482
    318 rdf:type schema:CreativeWork
    319 https://doi.org/10.1016/0192-0561(81)90022-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045258251
    320 rdf:type schema:CreativeWork
    321 https://doi.org/10.1016/0924-4247(90)87066-r schema:sameAs https://app.dimensions.ai/details/publication/pub.1040479293
    322 rdf:type schema:CreativeWork
    323 https://doi.org/10.1016/0925-4005(94)01196-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018195365
    324 rdf:type schema:CreativeWork
    325 https://doi.org/10.1016/0968-0004(82)90184-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047375567
    326 rdf:type schema:CreativeWork
    327 https://doi.org/10.1016/j.canlet.2006.12.014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045175509
    328 rdf:type schema:CreativeWork
    329 https://doi.org/10.1016/j.chroma.2007.06.025 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004050256
    330 rdf:type schema:CreativeWork
    331 https://doi.org/10.1016/j.humpath.2006.01.026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008800830
    332 rdf:type schema:CreativeWork
    333 https://doi.org/10.1016/j.yexcr.2004.08.039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034627415
    334 rdf:type schema:CreativeWork
    335 https://doi.org/10.1016/s0002-9378(16)36649-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020750575
    336 rdf:type schema:CreativeWork
    337 https://doi.org/10.1016/s0002-9378(99)70622-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044544971
    338 rdf:type schema:CreativeWork
    339 https://doi.org/10.1016/s0002-9440(10)64348-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021815897
    340 rdf:type schema:CreativeWork
    341 https://doi.org/10.1016/s0002-9440(10)64706-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028565116
    342 rdf:type schema:CreativeWork
    343 https://doi.org/10.1016/s0006-3495(01)76035-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009663804
    344 rdf:type schema:CreativeWork
    345 https://doi.org/10.1016/s0006-3495(03)75069-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004177051
    346 rdf:type schema:CreativeWork
    347 https://doi.org/10.1016/s0006-3495(95)80443-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001259652
    348 rdf:type schema:CreativeWork
    349 https://doi.org/10.1016/s0006-3495(96)79538-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000069098
    350 rdf:type schema:CreativeWork
    351 https://doi.org/10.1016/s0022-1759(83)80016-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035718539
    352 rdf:type schema:CreativeWork
    353 https://doi.org/10.1016/s0140-6736(03)12798-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027518865
    354 rdf:type schema:CreativeWork
    355 https://doi.org/10.1016/s0140-6736(69)91642-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049851111
    356 rdf:type schema:CreativeWork
    357 https://doi.org/10.1016/s0140-6736(73)91675-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024882636
    358 rdf:type schema:CreativeWork
    359 https://doi.org/10.1016/s0140-6736(84)90182-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1015306892
    360 rdf:type schema:CreativeWork
    361 https://doi.org/10.1016/s0140-6736(84)90875-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020585609
    362 rdf:type schema:CreativeWork
    363 https://doi.org/10.1016/s0140-6736(88)91295-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032333211
    364 rdf:type schema:CreativeWork
    365 https://doi.org/10.1016/s0140-6736(89)90509-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038476984
    366 rdf:type schema:CreativeWork
    367 https://doi.org/10.1016/s0140-6736(89)91723-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012742575
    368 rdf:type schema:CreativeWork
    369 https://doi.org/10.1016/s0140-6736(89)91969-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005136045
    370 rdf:type schema:CreativeWork
    371 https://doi.org/10.1016/s0165-022x(98)00010-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011857171
    372 rdf:type schema:CreativeWork
    373 https://doi.org/10.1016/s0378-4347(98)00308-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009515152
    374 rdf:type schema:CreativeWork
    375 https://doi.org/10.1016/s1028-4559(09)60184-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047390250
    376 rdf:type schema:CreativeWork
    377 https://doi.org/10.1021/ac001109s schema:sameAs https://app.dimensions.ai/details/publication/pub.1054972555
    378 rdf:type schema:CreativeWork
    379 https://doi.org/10.1021/ac0255330 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054994040
    380 rdf:type schema:CreativeWork
    381 https://doi.org/10.1021/ac048196z schema:sameAs https://app.dimensions.ai/details/publication/pub.1054996007
    382 rdf:type schema:CreativeWork
    383 https://doi.org/10.1021/ac049429p schema:sameAs https://app.dimensions.ai/details/publication/pub.1054996554
    384 rdf:type schema:CreativeWork
    385 https://doi.org/10.1021/ac058013o schema:sameAs https://app.dimensions.ai/details/publication/pub.1054997945
    386 rdf:type schema:CreativeWork
    387 https://doi.org/10.1021/ac950766v schema:sameAs https://app.dimensions.ai/details/publication/pub.1055072296
    388 rdf:type schema:CreativeWork
    389 https://doi.org/10.1021/ac9606564 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055072918
    390 rdf:type schema:CreativeWork
    391 https://doi.org/10.1021/ac971063b schema:sameAs https://app.dimensions.ai/details/publication/pub.1055074435
    392 rdf:type schema:CreativeWork
    393 https://doi.org/10.1021/ac990504j schema:sameAs https://app.dimensions.ai/details/publication/pub.1002677891
    394 rdf:type schema:CreativeWork
    395 https://doi.org/10.1021/bp0256216 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032632659
    396 rdf:type schema:CreativeWork
    397 https://doi.org/10.1021/ja973071f schema:sameAs https://app.dimensions.ai/details/publication/pub.1055868473
    398 rdf:type schema:CreativeWork
    399 https://doi.org/10.1021/la000600b schema:sameAs https://app.dimensions.ai/details/publication/pub.1008986356
    400 rdf:type schema:CreativeWork
    401 https://doi.org/10.1034/j.1399-0004.2001.600209.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1029889629
    402 rdf:type schema:CreativeWork
    403 https://doi.org/10.1039/b400455h schema:sameAs https://app.dimensions.ai/details/publication/pub.1015749457
    404 rdf:type schema:CreativeWork
    405 https://doi.org/10.1056/nejm198503143121103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032479478
    406 rdf:type schema:CreativeWork
    407 https://doi.org/10.1056/nejm198710153171603 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014157998
    408 rdf:type schema:CreativeWork
    409 https://doi.org/10.1056/nejm198809013190903 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019810917
    410 rdf:type schema:CreativeWork
    411 https://doi.org/10.1056/nejmoa050995 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007158962
    412 rdf:type schema:CreativeWork
    413 https://doi.org/10.1063/1.1356728 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057698373
    414 rdf:type schema:CreativeWork
    415 https://doi.org/10.1063/1.329003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057931806
    416 rdf:type schema:CreativeWork
    417 https://doi.org/10.1073/pnas.0404036101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002440023
    418 rdf:type schema:CreativeWork
    419 https://doi.org/10.1073/pnas.040562297 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031059605
    420 rdf:type schema:CreativeWork
    421 https://doi.org/10.1073/pnas.051631798 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008647723
    422 rdf:type schema:CreativeWork
    423 https://doi.org/10.1073/pnas.76.3.1453 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027184311
    424 rdf:type schema:CreativeWork
    425 https://doi.org/10.1073/pnas.78.5.3039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018965657
    426 rdf:type schema:CreativeWork
    427 https://doi.org/10.1073/pnas.78.8.5147 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019158190
    428 rdf:type schema:CreativeWork
    429 https://doi.org/10.1073/pnas.83.9.2934 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046429766
    430 rdf:type schema:CreativeWork
    431 https://doi.org/10.1073/pnas.85.23.9138 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053213537
    432 rdf:type schema:CreativeWork
    433 https://doi.org/10.1073/pnas.87.9.3279 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004598196
    434 rdf:type schema:CreativeWork
    435 https://doi.org/10.1073/pnas.91.13.5740 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041174406
    436 rdf:type schema:CreativeWork
    437 https://doi.org/10.1073/pnas.93.16.8508 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015938894
    438 rdf:type schema:CreativeWork
    439 https://doi.org/10.1073/pnas.96.1.11 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048334616
    440 rdf:type schema:CreativeWork
    441 https://doi.org/10.1073/pnas.96.10.5545 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004720306
    442 rdf:type schema:CreativeWork
    443 https://doi.org/10.1073/pnas.96.24.13762 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011096471
    444 rdf:type schema:CreativeWork
    445 https://doi.org/10.1074/mcp.m600246-mcp200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003502507
    446 rdf:type schema:CreativeWork
    447 https://doi.org/10.1084/jem.160.3.633 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002142674
    448 rdf:type schema:CreativeWork
    449 https://doi.org/10.1086/514885 schema:sameAs https://app.dimensions.ai/details/publication/pub.1058789371
    450 rdf:type schema:CreativeWork
    451 https://doi.org/10.1088/0960-1317/4/4/001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027147727
    452 rdf:type schema:CreativeWork
    453 https://doi.org/10.1088/0960-1317/4/4/003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023578349
    454 rdf:type schema:CreativeWork
    455 https://doi.org/10.1088/0960-1317/8/1/004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032633956
    456 rdf:type schema:CreativeWork
    457 https://doi.org/10.1088/0960-1317/9/4/318 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003669344
    458 rdf:type schema:CreativeWork
    459 https://doi.org/10.1093/hmg/1.5.307 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059643892
    460 rdf:type schema:CreativeWork
    461 https://doi.org/10.1093/molehr/gag027 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016394926
    462 rdf:type schema:CreativeWork
    463 https://doi.org/10.1093/nar/14.3.1325 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014614266
    464 rdf:type schema:CreativeWork
    465 https://doi.org/10.1093/nar/16.23.11141 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015096617
    466 rdf:type schema:CreativeWork
    467 https://doi.org/10.1093/nar/gkl740 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009210837
    468 rdf:type schema:CreativeWork
    469 https://doi.org/10.1093/oxfordjournals.humrep.a137290 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077464208
    470 rdf:type schema:CreativeWork
    471 https://doi.org/10.1097/00007890-198408000-00009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048888098
    472 rdf:type schema:CreativeWork
    473 https://doi.org/10.1101/sqb.1986.051.01.032 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060405782
    474 rdf:type schema:CreativeWork
    475 https://doi.org/10.1103/physrevlett.79.2149 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060815844
    476 rdf:type schema:CreativeWork
    477 https://doi.org/10.1103/physrevlett.80.1552 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060816922
    478 rdf:type schema:CreativeWork
    479 https://doi.org/10.1103/physrevlett.88.128103 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060824650
    480 rdf:type schema:CreativeWork
    481 https://doi.org/10.1109/28.54263 schema:sameAs https://app.dimensions.ai/details/publication/pub.1061142682
    482 rdf:type schema:CreativeWork
    483 https://doi.org/10.1109/77.828383 schema:sameAs https://app.dimensions.ai/details/publication/pub.1061226553
    484 rdf:type schema:CreativeWork
    485 https://doi.org/10.1109/84.157362 schema:sameAs https://app.dimensions.ai/details/publication/pub.1061240456
    486 rdf:type schema:CreativeWork
    487 https://doi.org/10.1109/84.285720 schema:sameAs https://app.dimensions.ai/details/publication/pub.1061240486
    488 rdf:type schema:CreativeWork
    489 https://doi.org/10.1109/84.735347 schema:sameAs https://app.dimensions.ai/details/publication/pub.1061240655
    490 rdf:type schema:CreativeWork
    491 https://doi.org/10.1109/84.982861 schema:sameAs https://app.dimensions.ai/details/publication/pub.1061240867
    492 rdf:type schema:CreativeWork
    493 https://doi.org/10.1109/jmems.2003.818457 schema:sameAs https://app.dimensions.ai/details/publication/pub.1061289825
    494 rdf:type schema:CreativeWork
    495 https://doi.org/10.1109/tnb.2004.837903 schema:sameAs https://app.dimensions.ai/details/publication/pub.1061713652
    496 rdf:type schema:CreativeWork
    497 https://doi.org/10.1111/j.1399-0039.1980.tb00313.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1003689159
    498 rdf:type schema:CreativeWork
    499 https://doi.org/10.1111/j.1471-0528.1995.tb09065.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1051106449
    500 rdf:type schema:CreativeWork
    501 https://doi.org/10.1116/1.571222 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062181269
    502 rdf:type schema:CreativeWork
    503 https://doi.org/10.1126/science.1094567 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042009152
    504 rdf:type schema:CreativeWork
    505 https://doi.org/10.1126/science.2416058 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062536806
    506 rdf:type schema:CreativeWork
    507 https://doi.org/10.1126/science.276.5313.779 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062556573
    508 rdf:type schema:CreativeWork
    509 https://doi.org/10.1126/science.283.5400.346 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062563859
    510 rdf:type schema:CreativeWork
    511 https://doi.org/10.1126/science.285.5424.83 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024794668
    512 rdf:type schema:CreativeWork
    513 https://doi.org/10.1126/science.288.5468.1026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062569397
    514 rdf:type schema:CreativeWork
    515 https://doi.org/10.1128/mcb.2.5.578 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042392200
    516 rdf:type schema:CreativeWork
    517 https://doi.org/10.1136/jmg.12.3.230 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043539854
    518 rdf:type schema:CreativeWork
    519 https://doi.org/10.1146/annurev.bioeng.7.011205.135108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039926044
    520 rdf:type schema:CreativeWork
    521 https://doi.org/10.1158/0008-5472.can-04-3196 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047207617
    522 rdf:type schema:CreativeWork
    523 https://doi.org/10.1159/000082432 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045052290
    524 rdf:type schema:CreativeWork
    525 https://doi.org/10.1172/jci113409 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040139164
    526 rdf:type schema:CreativeWork
    527 https://doi.org/10.1172/jci114188 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030912262
    528 rdf:type schema:CreativeWork
    529 https://doi.org/10.1177/33.10.3900197 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039886282
    530 rdf:type schema:CreativeWork
    531 https://doi.org/10.3109/00313028409067911 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002441520
    532 rdf:type schema:CreativeWork
    533 https://www.grid.ac/institutes/grid.32224.35 schema:Organization
    534 https://www.grid.ac/institutes/grid.494219.3 schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...