Therapeutic compositions and methods for treating infections


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

Rick Tarleton , Samarchith Kurup

ABSTRACT

This disclosure describes, in one aspect, a composition that includes a transgenic pathogen that expresses a heterologous pathogen associated molecular pattern (PAMP). In some embodiments, the pathogen may be attenuated. In some embodiments, the pathogen can include T. cruzi. In another aspect, this disclosure describes a method of treating an infection in a subject. Generally, the method includes administering to the subject, in an amount effective to treat the infection, a pathogen genetically modified to express a pathogen-associated molecular pattern (PAMP) not natively expressed by the pathogen. More... »

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