Inhibitors of influenza viruses replication


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

Kwame W. Nti-Addae , Michael Waldo , Simon Adam O'Neil , John Gregg Van Alsten , Dainius Macikenas , Praveen Mudunuri , Yi Shi , Mark Willem Ledeboer , Valdas Jurkauskas , Ales Medek , Steven Jones , Randal Byrn , Mohammed Asmal , Sarah Marie Robertson , Wanjung Tsai

ABSTRACT

Polymorphic forms of Compound (1) or a pharmaceutically acceptable salt thereof, wherein Compound (1) is represented by the following structural formula: are Form A of HCl salt of Compound (1).½H2O, Form F of HCl salt of Compound (1).3H2O, Form D of HCl salt of Compound (1), Form A of Compound (1), and Form A of tosylate salt of Compound (1). Such polymorphic forms are employed for treating influenza, inhibiting the replication of influenza viruses, or reducing the amount of influenza viruses in a biological sample or in a subject. More... »

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