Cell culture platform for single cell sorting and enhanced reprogramming of iPSCs


Ontology type: sgo:Patent     


Patent Info

DATE

2017-08-15T00:00

AUTHORS

Bahram Valamehr , Ramzey Abujarour , Peter Flynn

ABSTRACT

The invention provides cell culture conditions for culturing stem cells, including feeder-free conditions for generating and culturing human induced pluripotent stem cells (iPSCs). More particularly, the invention provides a culture platform that allows long-term culture of pluripotent cells in a feeder-free environment; reprogramming of cells in a feeder-free environment; single-cell dissociation of pluripotent cells; cell sorting of pluripotent cells; maintenance of an undifferentiated status; improved efficiency of reprogramming; and generation of a naïve pluripotent cell. More... »

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