Substituted bicyclic compounds as bromodomain inhibitors


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

Shuang Liu , John Frederick Quinn , Bryan Cordell Duffy , Ruifang Wang , May Xiaowu JIANG , Gregory Scott Martin , He Zhao , Michael Ellis , Gregory Steven Wagner , Peter Ronald Young

ABSTRACT

The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/2464", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "name": "Shuang Liu", 
        "type": "Person"
      }, 
      {
        "name": "John Frederick Quinn", 
        "type": "Person"
      }, 
      {
        "name": "Bryan Cordell Duffy", 
        "type": "Person"
      }, 
      {
        "name": "Ruifang Wang", 
        "type": "Person"
      }, 
      {
        "name": "May Xiaowu JIANG", 
        "type": "Person"
      }, 
      {
        "name": "Gregory Scott Martin", 
        "type": "Person"
      }, 
      {
        "name": "He Zhao", 
        "type": "Person"
      }, 
      {
        "name": "Michael Ellis", 
        "type": "Person"
      }, 
      {
        "name": "Gregory Steven Wagner", 
        "type": "Person"
      }, 
      {
        "name": "Peter Ronald Young", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s10753-012-9519-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000105909", 
          "https://doi.org/10.1007/s10753-012-9519-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10753-012-9519-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000105909", 
          "https://doi.org/10.1007/s10753-012-9519-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1196/annals.1372.039", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000129161"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0023656", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000155499"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00417-012-2092-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000193718", 
          "https://doi.org/10.1007/s00417-012-2092-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/rheumatology/keg459", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000348279"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1517/13543784.8.9.1327", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000394176"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1346-8138.1998.tb02375.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001138030"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1242/dev.004481", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001424180"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature09504", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001851540", 
          "https://doi.org/10.1038/nature09504"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0018909", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002616102"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bmcl.2012.02.041", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002626433"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1084/jem.192.6.899", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002841485"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10875-012-9706-z", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003227365", 
          "https://doi.org/10.1007/s10875-012-9706-z"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/cdd.2011.17", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003477526", 
          "https://doi.org/10.1038/cdd.2011.17"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jaut.2012.07.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004684624"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2012.06.045", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004883182"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2353/ajpath.2009.090319", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005107085"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2217/clp.10.37", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005849919"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ibd.20148", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006405097"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.tips.2011.12.002", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006448003"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00415-010-5836-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006471313", 
          "https://doi.org/10.1007/s00415-010-5836-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jaut.2010.12.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006498064"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1046/j.1365-4362.2001.01083.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007496941"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2249.2009.03947.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007613291"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.joca.2011.01.018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008108537"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2141.2008.07161.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008259678"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2249.2011.04510.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008703005"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2230.2010.03972.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009161445"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/01.mlg.0000161334.67977.5d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009886926"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s13148-011-0026-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010293021", 
          "https://doi.org/10.1007/s13148-011-0026-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jvi.02468-08", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010336351"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.0000049742.68848.99", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011078906"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1084/jem.193.6.713", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011193667"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/00365513.2011.652158", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011284973"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1044-5323(02)00125-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011548907"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00296-011-1995-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012271508", 
          "https://doi.org/10.1007/s00296-011-1995-7"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0056514", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012394551"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jvi.01316-08", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012491569"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m112.413047", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012692612"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00277-008-0535-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012819123", 
          "https://doi.org/10.1007/s00277-008-0535-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00277-008-0535-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012819123", 
          "https://doi.org/10.1007/s00277-008-0535-3"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bmcl.2012.01.125", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013024286"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jacc.2004.07.047", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013250329"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.109.872903", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013624700"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.atv.19.6.1518", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013661868"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/ajg.2009.271", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014339508", 
          "https://doi.org/10.1038/ajg.2009.271"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/eji.201040391", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014845015"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1111/j.1523-1755.2004.00512.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014853341", 
          "https://doi.org/10.1111/j.1523-1755.2004.00512.x"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jm200640v", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014962424"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1039/c2md20189e", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015340401"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1399-3038.2011.01198.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015419314"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00109-011-0837-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015571426", 
          "https://doi.org/10.1007/s00109-011-0837-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci115411", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016321463"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10875-012-9780-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017371763", 
          "https://doi.org/10.1007/s10875-012-9780-2"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/cyto.2002.1039", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017471537"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jpedsurg.2004.06.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017597625"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0272-6386(95)90157-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018352557"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/art.25003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019537340"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature10351", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019649945", 
          "https://doi.org/10.1038/nature10351"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2005.02.8589", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020057203"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3109/00207450903428970", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020096258"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/2040620715576662", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020792420"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj20090928", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021145702"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.urology.2006.04.033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021403224"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/cvr/cvr148", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021560410"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1634/theoncologist.2010-0212", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022108823"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.0902-4441.2005.t01-1-ejh2437.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022212451"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1601-0825.2005.01165.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022309784"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1755-148x.2009.00649.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023027036"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s11164-011-0360-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023757810", 
          "https://doi.org/10.1007/s11164-011-0360-5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/mi.2009.5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023802098", 
          "https://doi.org/10.1038/mi.2009.5"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00595-010-4300-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024739436", 
          "https://doi.org/10.1007/s00595-010-4300-6"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jm200108t", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025618144"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cell.2011.08.017", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026115083"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1586/eci.11.7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026560618"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.semcancer.2006.07.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026605265"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature10509", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026728956", 
          "https://doi.org/10.1038/nature10509"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/rheumatology/ken468", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027277171"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1189/jlb.0312165", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027321056"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gks976", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027886931"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m112.410746", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028060443"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/jmcb/mjr042", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028673905"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature10334", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030076294", 
          "https://doi.org/10.1038/nature10334"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.febslet.2010.05.030", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030271685"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ctrv.2012.06.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030803686"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jneuroim.2008.02.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031560858"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1634/theoncologist.5-suppl_1-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031700568"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00403-010-1033-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031744711", 
          "https://doi.org/10.1007/s00403-010-1033-8"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2008-08-172155", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031848248"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ja412434f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031849993"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1097-2765(00)80139-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031994520"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ijc.21669", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032406417"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1634/theoncologist.5-suppl_1-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032506924"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1200/jco.2009.26.1347", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032892538"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.exer.2010.04.009", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032933636"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.cdd.4402008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034892015", 
          "https://doi.org/10.1038/sj.cdd.4402008"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1159/000237257", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036213454"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/rheumatology/ken349", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036238315"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1440-1797.2010.01343.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036626853"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1212264109", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037215264"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/29788", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037262209", 
          "https://doi.org/10.1038/29788"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.exphem.2012.08.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037688825"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bmcl.2010.07.008", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038018165"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrd4286", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038849480", 
          "https://doi.org/10.1038/nrd4286"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2003-06-2116", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039291918"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/2159-8290.cd-11-0220", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039610161"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ajpath.2013.04.020", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040308342"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/path.1588", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040719033"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.1108190108", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041102152"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.tips.2008.03.003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042076553"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci115950", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042252284"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0163-4453(98)91120-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043428808"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/ibd.20475", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043470749"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1182/blood-2012-02-413021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043680109"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/gut.2005.079343", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043790509"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.ppat.1002334", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043816338"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m112.359505", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043907936"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jm301588r", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044763054"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc3256", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044768219", 
          "https://doi.org/10.1038/nrc3256"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jvi.00502-06", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044978788"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ijcard.2012.01.035", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046016453"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1371/journal.pone.0005903", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046254323"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1172/jci5624", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046321148"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/cs20080581", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046352368"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1167/iovs.10-6272", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047056364"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/rheumatology/ken489", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047619133"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2169/internalmedicine.32.189", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048307603"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1038/emboj.2012.233", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049083427"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-2249.2010.04236.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049628585"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s10165-012-0691-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049708190", 
          "https://doi.org/10.1007/s10165-012-0691-0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrc2439", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049875030", 
          "https://doi.org/10.1038/nrc2439"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1365-3083.2011.02536.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050097340"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.r700001200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050432137"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cancergencyto.2010.06.007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050573999"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/cir.0b013e31823ac046", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051424218"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1084/jem.186.1.131", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051770127"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m002285200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052054996"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/gks342", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052101846"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nrcardio.2010.200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052481598", 
          "https://doi.org/10.1038/nrcardio.2010.200"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0304-3835(99)00385-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053409458"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.trstmh.2008.01.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054751599"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jm300915b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055953217"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jo00804a007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055986555"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1158/1538-7445.am2012-2185", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063242705"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.atv.15.11.1882", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1063333905"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1210/jc.2009-1719", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064291639"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1212/wnl.57.9.1561", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1064380274"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1517/14712598.2012.707178", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1067588650"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1902/jop.2004.75.1.37", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1068735047"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2174/156652408785160998", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1069185930"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2340/00015555-1228", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1070751341"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3892/ol.2012.695", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071525638"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3899/jrheum.100293", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071542223"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4161/cbt.4.3.1497", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1072293677"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4161/cc.8.17.9416", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1072300237"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.4161/epi.5.2.10942", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1072302979"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "description": "

The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.

\"embedded

", "id": "sg:patent.US-9662311-B2", "keywords": [ "compound", "bromodomains", "invention", "inhibition", "protein function", "binding", "pharmaceutical", "composition", "therapy" ], "name": "Substituted bicyclic compounds as bromodomain inhibitors", "sameAs": [ "https://app.dimensions.ai/details/patent/US-9662311-B2" ], "sdDataset": "patents", "sdDatePublished": "2019-03-07T15:37", "sdLicense": "https://scigraph.springernature.com/explorer/license/", "sdPublisher": { "name": "Springer Nature - SN SciGraph project", "type": "Organization" }, "sdSource": "s3://com.uberresearch.data.dev.patents-pipeline/full_run_10/sn-export/5eb3e5a348d7f117b22cc85fb0b02730/0000100128-0000348334/json_export_ec415531.jsonl", "type": "Patent" } ]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/patent.US-9662311-B2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/patent.US-9662311-B2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/patent.US-9662311-B2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/patent.US-9662311-B2'


 

This table displays all metadata directly associated to this object as RDF triples.

556 TRIPLES      13 PREDICATES      176 URIs      16 LITERALS      2 BLANK NODES

Subject Predicate Object
1 sg:patent.US-9662311-B2 schema:about anzsrc-for:2464
2 schema:author N869d27ecec1e470a9e905f95294c64ab
3 schema:citation sg:pub.10.1007/s00109-011-0837-0
4 sg:pub.10.1007/s00277-008-0535-3
5 sg:pub.10.1007/s00296-011-1995-7
6 sg:pub.10.1007/s00403-010-1033-8
7 sg:pub.10.1007/s00415-010-5836-5
8 sg:pub.10.1007/s00417-012-2092-7
9 sg:pub.10.1007/s00595-010-4300-6
10 sg:pub.10.1007/s10165-012-0691-0
11 sg:pub.10.1007/s10753-012-9519-5
12 sg:pub.10.1007/s10875-012-9706-z
13 sg:pub.10.1007/s10875-012-9780-2
14 sg:pub.10.1007/s11164-011-0360-5
15 sg:pub.10.1007/s13148-011-0026-6
16 sg:pub.10.1038/29788
17 sg:pub.10.1038/ajg.2009.271
18 sg:pub.10.1038/cdd.2011.17
19 sg:pub.10.1038/mi.2009.5
20 sg:pub.10.1038/nature09504
21 sg:pub.10.1038/nature10334
22 sg:pub.10.1038/nature10351
23 sg:pub.10.1038/nature10509
24 sg:pub.10.1038/nrc2439
25 sg:pub.10.1038/nrc3256
26 sg:pub.10.1038/nrcardio.2010.200
27 sg:pub.10.1038/nrd4286
28 sg:pub.10.1038/sj.cdd.4402008
29 sg:pub.10.1111/j.1523-1755.2004.00512.x
30 https://doi.org/10.1002/art.25003
31 https://doi.org/10.1002/eji.201040391
32 https://doi.org/10.1002/ibd.20148
33 https://doi.org/10.1002/ibd.20475
34 https://doi.org/10.1002/ijc.21669
35 https://doi.org/10.1002/path.1588
36 https://doi.org/10.1006/cyto.2002.1039
37 https://doi.org/10.1016/0272-6386(95)90157-4
38 https://doi.org/10.1016/j.ajpath.2013.04.020
39 https://doi.org/10.1016/j.bmcl.2010.07.008
40 https://doi.org/10.1016/j.bmcl.2012.01.125
41 https://doi.org/10.1016/j.bmcl.2012.02.041
42 https://doi.org/10.1016/j.cancergencyto.2010.06.007
43 https://doi.org/10.1016/j.cell.2011.08.017
44 https://doi.org/10.1016/j.cell.2012.06.045
45 https://doi.org/10.1016/j.ctrv.2012.06.007
46 https://doi.org/10.1016/j.exer.2010.04.009
47 https://doi.org/10.1016/j.exphem.2012.08.008
48 https://doi.org/10.1016/j.febslet.2010.05.030
49 https://doi.org/10.1016/j.ijcard.2012.01.035
50 https://doi.org/10.1016/j.jacc.2004.07.047
51 https://doi.org/10.1016/j.jaut.2010.12.001
52 https://doi.org/10.1016/j.jaut.2012.07.004
53 https://doi.org/10.1016/j.jneuroim.2008.02.008
54 https://doi.org/10.1016/j.joca.2011.01.018
55 https://doi.org/10.1016/j.jpedsurg.2004.06.015
56 https://doi.org/10.1016/j.semcancer.2006.07.015
57 https://doi.org/10.1016/j.tips.2008.03.003
58 https://doi.org/10.1016/j.tips.2011.12.002
59 https://doi.org/10.1016/j.trstmh.2008.01.004
60 https://doi.org/10.1016/j.urology.2006.04.033
61 https://doi.org/10.1016/s0163-4453(98)91120-3
62 https://doi.org/10.1016/s0304-3835(99)00385-7
63 https://doi.org/10.1016/s1044-5323(02)00125-2
64 https://doi.org/10.1016/s1097-2765(00)80139-2
65 https://doi.org/10.1021/ja412434f
66 https://doi.org/10.1021/jm200108t
67 https://doi.org/10.1021/jm200640v
68 https://doi.org/10.1021/jm300915b
69 https://doi.org/10.1021/jm301588r
70 https://doi.org/10.1021/jo00804a007
71 https://doi.org/10.1038/emboj.2012.233
72 https://doi.org/10.1039/c2md20189e
73 https://doi.org/10.1042/bj20090928
74 https://doi.org/10.1042/cs20080581
75 https://doi.org/10.1046/j.1365-4362.2001.01083.x
76 https://doi.org/10.1073/pnas.1108190108
77 https://doi.org/10.1073/pnas.1212264109
78 https://doi.org/10.1074/jbc.m002285200
79 https://doi.org/10.1074/jbc.m112.359505
80 https://doi.org/10.1074/jbc.m112.410746
81 https://doi.org/10.1074/jbc.m112.413047
82 https://doi.org/10.1074/jbc.r700001200
83 https://doi.org/10.1084/jem.186.1.131
84 https://doi.org/10.1084/jem.192.6.899
85 https://doi.org/10.1084/jem.193.6.713
86 https://doi.org/10.1093/cvr/cvr148
87 https://doi.org/10.1093/jmcb/mjr042
88 https://doi.org/10.1093/nar/gks342
89 https://doi.org/10.1093/nar/gks976
90 https://doi.org/10.1093/rheumatology/keg459
91 https://doi.org/10.1093/rheumatology/ken349
92 https://doi.org/10.1093/rheumatology/ken468
93 https://doi.org/10.1093/rheumatology/ken489
94 https://doi.org/10.1097/01.mlg.0000161334.67977.5d
95 https://doi.org/10.1111/j.0902-4441.2005.t01-1-ejh2437.x
96 https://doi.org/10.1111/j.1346-8138.1998.tb02375.x
97 https://doi.org/10.1111/j.1365-2141.2008.07161.x
98 https://doi.org/10.1111/j.1365-2230.2010.03972.x
99 https://doi.org/10.1111/j.1365-2249.2009.03947.x
100 https://doi.org/10.1111/j.1365-2249.2010.04236.x
101 https://doi.org/10.1111/j.1365-2249.2011.04510.x
102 https://doi.org/10.1111/j.1365-3083.2011.02536.x
103 https://doi.org/10.1111/j.1399-3038.2011.01198.x
104 https://doi.org/10.1111/j.1440-1797.2010.01343.x
105 https://doi.org/10.1111/j.1601-0825.2005.01165.x
106 https://doi.org/10.1111/j.1755-148x.2009.00649.x
107 https://doi.org/10.1128/jvi.00502-06
108 https://doi.org/10.1128/jvi.01316-08
109 https://doi.org/10.1128/jvi.02468-08
110 https://doi.org/10.1136/gut.2005.079343
111 https://doi.org/10.1158/1538-7445.am2012-2185
112 https://doi.org/10.1158/2159-8290.cd-11-0220
113 https://doi.org/10.1159/000237257
114 https://doi.org/10.1161/01.atv.15.11.1882
115 https://doi.org/10.1161/01.atv.19.6.1518
116 https://doi.org/10.1161/01.cir.0000049742.68848.99
117 https://doi.org/10.1161/cir.0b013e31823ac046
118 https://doi.org/10.1161/circulationaha.109.872903
119 https://doi.org/10.1167/iovs.10-6272
120 https://doi.org/10.1172/jci115411
121 https://doi.org/10.1172/jci115950
122 https://doi.org/10.1172/jci5624
123 https://doi.org/10.1177/2040620715576662
124 https://doi.org/10.1182/blood-2003-06-2116
125 https://doi.org/10.1182/blood-2008-08-172155
126 https://doi.org/10.1182/blood-2012-02-413021
127 https://doi.org/10.1189/jlb.0312165
128 https://doi.org/10.1196/annals.1372.039
129 https://doi.org/10.1200/jco.2005.02.8589
130 https://doi.org/10.1200/jco.2009.26.1347
131 https://doi.org/10.1210/jc.2009-1719
132 https://doi.org/10.1212/wnl.57.9.1561
133 https://doi.org/10.1242/dev.004481
134 https://doi.org/10.1371/journal.pone.0005903
135 https://doi.org/10.1371/journal.pone.0018909
136 https://doi.org/10.1371/journal.pone.0023656
137 https://doi.org/10.1371/journal.pone.0056514
138 https://doi.org/10.1371/journal.ppat.1002334
139 https://doi.org/10.1517/13543784.8.9.1327
140 https://doi.org/10.1517/14712598.2012.707178
141 https://doi.org/10.1586/eci.11.7
142 https://doi.org/10.1634/theoncologist.2010-0212
143 https://doi.org/10.1634/theoncologist.5-suppl_1-1
144 https://doi.org/10.1634/theoncologist.5-suppl_1-3
145 https://doi.org/10.1902/jop.2004.75.1.37
146 https://doi.org/10.2169/internalmedicine.32.189
147 https://doi.org/10.2174/156652408785160998
148 https://doi.org/10.2217/clp.10.37
149 https://doi.org/10.2340/00015555-1228
150 https://doi.org/10.2353/ajpath.2009.090319
151 https://doi.org/10.3109/00207450903428970
152 https://doi.org/10.3109/00365513.2011.652158
153 https://doi.org/10.3892/ol.2012.695
154 https://doi.org/10.3899/jrheum.100293
155 https://doi.org/10.4161/cbt.4.3.1497
156 https://doi.org/10.4161/cc.8.17.9416
157 https://doi.org/10.4161/epi.5.2.10942
158 schema:description <p id="p-0001" num="0000">The invention relates to substituted bicyclic compounds, which are useful for inhibition of BET protein function by binding to bromodomains, pharmaceutical compositions comprising these compounds, and use of the compounds and compositions in therapy.</p><p id="p-0002" num="0000"><chemistry id="CHEM-US-00001" num="00001"><img id="EMI-C00001" he="25.23mm" wi="56.73mm" file="US09662311-20170530-C00001.TIF" alt="embedded image" img-content="chem" img-format="tif" orientation="portrait" inline="no"/><attachments><attachment idref="CHEM-US-00001" attachment-type="cdx" file="US09662311-20170530-C00001.CDX"/><attachment idref="CHEM-US-00001" attachment-type="mol" file="US09662311-20170530-C00001.MOL"/></attachments></chemistry></p>
159 schema:keywords binding
160 bromodomains
161 composition
162 compound
163 inhibition
164 invention
165 pharmaceutical
166 protein function
167 therapy
168 schema:name Substituted bicyclic compounds as bromodomain inhibitors
169 schema:sameAs https://app.dimensions.ai/details/patent/US-9662311-B2
170 schema:sdDatePublished 2019-03-07T15:37
171 schema:sdLicense https://scigraph.springernature.com/explorer/license/
172 schema:sdPublisher N0605ae4f58f247068407b2ff4d84797d
173 sgo:license sg:explorer/license/
174 sgo:sdDataset patents
175 rdf:type sgo:Patent
176 N032d194a67fb4e97bbe22539c9fd3fd0 rdf:first N785038e7351448e3900b79ccd7da2e45
177 rdf:rest N65cdd9b45dad4412ba7ce55adbd84cf2
178 N0605ae4f58f247068407b2ff4d84797d schema:name Springer Nature - SN SciGraph project
179 rdf:type schema:Organization
180 N086256833e7c4b10891efab609370a9a schema:name Gregory Steven Wagner
181 rdf:type schema:Person
182 N129b8852801b460a9814a4247cc68c9e schema:name Ruifang Wang
183 rdf:type schema:Person
184 N249ea4b4c50641fb81583abc10e69c55 rdf:first N6680b01996874732841d66ae9023f986
185 rdf:rest N4b34ebfb8ffd41118aaefbf3a7e218c7
186 N434da5f9f141464893ba4b5eb5fb88f5 rdf:first N6a0b10a34c9b4929889f2912458ef6bb
187 rdf:rest N249ea4b4c50641fb81583abc10e69c55
188 N483a838bf82b41b0aa6af37cc9082611 rdf:first Nf98c907f6fba49ebb38520ab05f802fb
189 rdf:rest rdf:nil
190 N4b34ebfb8ffd41118aaefbf3a7e218c7 rdf:first N086256833e7c4b10891efab609370a9a
191 rdf:rest N483a838bf82b41b0aa6af37cc9082611
192 N65cdd9b45dad4412ba7ce55adbd84cf2 rdf:first Nb2d593f4310c426eb806b43764699da1
193 rdf:rest Ne77011df662e475fb5cb4f0996865dd3
194 N6680b01996874732841d66ae9023f986 schema:name Michael Ellis
195 rdf:type schema:Person
196 N6a0b10a34c9b4929889f2912458ef6bb schema:name He Zhao
197 rdf:type schema:Person
198 N785038e7351448e3900b79ccd7da2e45 schema:name John Frederick Quinn
199 rdf:type schema:Person
200 N7c3c84175e7b4751bdf3eef01acead69 schema:name Shuang Liu
201 rdf:type schema:Person
202 N8604e196791a4b3dbb5e146807cec842 rdf:first Nffcc7ab9956947529192a0b21ca74498
203 rdf:rest N434da5f9f141464893ba4b5eb5fb88f5
204 N869d27ecec1e470a9e905f95294c64ab rdf:first N7c3c84175e7b4751bdf3eef01acead69
205 rdf:rest N032d194a67fb4e97bbe22539c9fd3fd0
206 N97be528975a7411391441336b9a48104 rdf:first Ndd6ba755ee0f40aca88512e4c9c2777b
207 rdf:rest N8604e196791a4b3dbb5e146807cec842
208 Nb2d593f4310c426eb806b43764699da1 schema:name Bryan Cordell Duffy
209 rdf:type schema:Person
210 Ndd6ba755ee0f40aca88512e4c9c2777b schema:name May Xiaowu JIANG
211 rdf:type schema:Person
212 Ne77011df662e475fb5cb4f0996865dd3 rdf:first N129b8852801b460a9814a4247cc68c9e
213 rdf:rest N97be528975a7411391441336b9a48104
214 Nf98c907f6fba49ebb38520ab05f802fb schema:name Peter Ronald Young
215 rdf:type schema:Person
216 Nffcc7ab9956947529192a0b21ca74498 schema:name Gregory Scott Martin
217 rdf:type schema:Person
218 anzsrc-for:2464 schema:inDefinedTermSet anzsrc-for:
219 rdf:type schema:DefinedTerm
220 sg:pub.10.1007/s00109-011-0837-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015571426
221 https://doi.org/10.1007/s00109-011-0837-0
222 rdf:type schema:CreativeWork
223 sg:pub.10.1007/s00277-008-0535-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012819123
224 https://doi.org/10.1007/s00277-008-0535-3
225 rdf:type schema:CreativeWork
226 sg:pub.10.1007/s00296-011-1995-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012271508
227 https://doi.org/10.1007/s00296-011-1995-7
228 rdf:type schema:CreativeWork
229 sg:pub.10.1007/s00403-010-1033-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031744711
230 https://doi.org/10.1007/s00403-010-1033-8
231 rdf:type schema:CreativeWork
232 sg:pub.10.1007/s00415-010-5836-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006471313
233 https://doi.org/10.1007/s00415-010-5836-5
234 rdf:type schema:CreativeWork
235 sg:pub.10.1007/s00417-012-2092-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000193718
236 https://doi.org/10.1007/s00417-012-2092-7
237 rdf:type schema:CreativeWork
238 sg:pub.10.1007/s00595-010-4300-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024739436
239 https://doi.org/10.1007/s00595-010-4300-6
240 rdf:type schema:CreativeWork
241 sg:pub.10.1007/s10165-012-0691-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049708190
242 https://doi.org/10.1007/s10165-012-0691-0
243 rdf:type schema:CreativeWork
244 sg:pub.10.1007/s10753-012-9519-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000105909
245 https://doi.org/10.1007/s10753-012-9519-5
246 rdf:type schema:CreativeWork
247 sg:pub.10.1007/s10875-012-9706-z schema:sameAs https://app.dimensions.ai/details/publication/pub.1003227365
248 https://doi.org/10.1007/s10875-012-9706-z
249 rdf:type schema:CreativeWork
250 sg:pub.10.1007/s10875-012-9780-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017371763
251 https://doi.org/10.1007/s10875-012-9780-2
252 rdf:type schema:CreativeWork
253 sg:pub.10.1007/s11164-011-0360-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023757810
254 https://doi.org/10.1007/s11164-011-0360-5
255 rdf:type schema:CreativeWork
256 sg:pub.10.1007/s13148-011-0026-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010293021
257 https://doi.org/10.1007/s13148-011-0026-6
258 rdf:type schema:CreativeWork
259 sg:pub.10.1038/29788 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037262209
260 https://doi.org/10.1038/29788
261 rdf:type schema:CreativeWork
262 sg:pub.10.1038/ajg.2009.271 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014339508
263 https://doi.org/10.1038/ajg.2009.271
264 rdf:type schema:CreativeWork
265 sg:pub.10.1038/cdd.2011.17 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003477526
266 https://doi.org/10.1038/cdd.2011.17
267 rdf:type schema:CreativeWork
268 sg:pub.10.1038/mi.2009.5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023802098
269 https://doi.org/10.1038/mi.2009.5
270 rdf:type schema:CreativeWork
271 sg:pub.10.1038/nature09504 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001851540
272 https://doi.org/10.1038/nature09504
273 rdf:type schema:CreativeWork
274 sg:pub.10.1038/nature10334 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030076294
275 https://doi.org/10.1038/nature10334
276 rdf:type schema:CreativeWork
277 sg:pub.10.1038/nature10351 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019649945
278 https://doi.org/10.1038/nature10351
279 rdf:type schema:CreativeWork
280 sg:pub.10.1038/nature10509 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026728956
281 https://doi.org/10.1038/nature10509
282 rdf:type schema:CreativeWork
283 sg:pub.10.1038/nrc2439 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049875030
284 https://doi.org/10.1038/nrc2439
285 rdf:type schema:CreativeWork
286 sg:pub.10.1038/nrc3256 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044768219
287 https://doi.org/10.1038/nrc3256
288 rdf:type schema:CreativeWork
289 sg:pub.10.1038/nrcardio.2010.200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052481598
290 https://doi.org/10.1038/nrcardio.2010.200
291 rdf:type schema:CreativeWork
292 sg:pub.10.1038/nrd4286 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038849480
293 https://doi.org/10.1038/nrd4286
294 rdf:type schema:CreativeWork
295 sg:pub.10.1038/sj.cdd.4402008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034892015
296 https://doi.org/10.1038/sj.cdd.4402008
297 rdf:type schema:CreativeWork
298 sg:pub.10.1111/j.1523-1755.2004.00512.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1014853341
299 https://doi.org/10.1111/j.1523-1755.2004.00512.x
300 rdf:type schema:CreativeWork
301 https://doi.org/10.1002/art.25003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019537340
302 rdf:type schema:CreativeWork
303 https://doi.org/10.1002/eji.201040391 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014845015
304 rdf:type schema:CreativeWork
305 https://doi.org/10.1002/ibd.20148 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006405097
306 rdf:type schema:CreativeWork
307 https://doi.org/10.1002/ibd.20475 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043470749
308 rdf:type schema:CreativeWork
309 https://doi.org/10.1002/ijc.21669 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032406417
310 rdf:type schema:CreativeWork
311 https://doi.org/10.1002/path.1588 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040719033
312 rdf:type schema:CreativeWork
313 https://doi.org/10.1006/cyto.2002.1039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017471537
314 rdf:type schema:CreativeWork
315 https://doi.org/10.1016/0272-6386(95)90157-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018352557
316 rdf:type schema:CreativeWork
317 https://doi.org/10.1016/j.ajpath.2013.04.020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040308342
318 rdf:type schema:CreativeWork
319 https://doi.org/10.1016/j.bmcl.2010.07.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038018165
320 rdf:type schema:CreativeWork
321 https://doi.org/10.1016/j.bmcl.2012.01.125 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013024286
322 rdf:type schema:CreativeWork
323 https://doi.org/10.1016/j.bmcl.2012.02.041 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002626433
324 rdf:type schema:CreativeWork
325 https://doi.org/10.1016/j.cancergencyto.2010.06.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050573999
326 rdf:type schema:CreativeWork
327 https://doi.org/10.1016/j.cell.2011.08.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026115083
328 rdf:type schema:CreativeWork
329 https://doi.org/10.1016/j.cell.2012.06.045 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004883182
330 rdf:type schema:CreativeWork
331 https://doi.org/10.1016/j.ctrv.2012.06.007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030803686
332 rdf:type schema:CreativeWork
333 https://doi.org/10.1016/j.exer.2010.04.009 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032933636
334 rdf:type schema:CreativeWork
335 https://doi.org/10.1016/j.exphem.2012.08.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037688825
336 rdf:type schema:CreativeWork
337 https://doi.org/10.1016/j.febslet.2010.05.030 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030271685
338 rdf:type schema:CreativeWork
339 https://doi.org/10.1016/j.ijcard.2012.01.035 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046016453
340 rdf:type schema:CreativeWork
341 https://doi.org/10.1016/j.jacc.2004.07.047 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013250329
342 rdf:type schema:CreativeWork
343 https://doi.org/10.1016/j.jaut.2010.12.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006498064
344 rdf:type schema:CreativeWork
345 https://doi.org/10.1016/j.jaut.2012.07.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004684624
346 rdf:type schema:CreativeWork
347 https://doi.org/10.1016/j.jneuroim.2008.02.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031560858
348 rdf:type schema:CreativeWork
349 https://doi.org/10.1016/j.joca.2011.01.018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008108537
350 rdf:type schema:CreativeWork
351 https://doi.org/10.1016/j.jpedsurg.2004.06.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017597625
352 rdf:type schema:CreativeWork
353 https://doi.org/10.1016/j.semcancer.2006.07.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026605265
354 rdf:type schema:CreativeWork
355 https://doi.org/10.1016/j.tips.2008.03.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042076553
356 rdf:type schema:CreativeWork
357 https://doi.org/10.1016/j.tips.2011.12.002 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006448003
358 rdf:type schema:CreativeWork
359 https://doi.org/10.1016/j.trstmh.2008.01.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054751599
360 rdf:type schema:CreativeWork
361 https://doi.org/10.1016/j.urology.2006.04.033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021403224
362 rdf:type schema:CreativeWork
363 https://doi.org/10.1016/s0163-4453(98)91120-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043428808
364 rdf:type schema:CreativeWork
365 https://doi.org/10.1016/s0304-3835(99)00385-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053409458
366 rdf:type schema:CreativeWork
367 https://doi.org/10.1016/s1044-5323(02)00125-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011548907
368 rdf:type schema:CreativeWork
369 https://doi.org/10.1016/s1097-2765(00)80139-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031994520
370 rdf:type schema:CreativeWork
371 https://doi.org/10.1021/ja412434f schema:sameAs https://app.dimensions.ai/details/publication/pub.1031849993
372 rdf:type schema:CreativeWork
373 https://doi.org/10.1021/jm200108t schema:sameAs https://app.dimensions.ai/details/publication/pub.1025618144
374 rdf:type schema:CreativeWork
375 https://doi.org/10.1021/jm200640v schema:sameAs https://app.dimensions.ai/details/publication/pub.1014962424
376 rdf:type schema:CreativeWork
377 https://doi.org/10.1021/jm300915b schema:sameAs https://app.dimensions.ai/details/publication/pub.1055953217
378 rdf:type schema:CreativeWork
379 https://doi.org/10.1021/jm301588r schema:sameAs https://app.dimensions.ai/details/publication/pub.1044763054
380 rdf:type schema:CreativeWork
381 https://doi.org/10.1021/jo00804a007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055986555
382 rdf:type schema:CreativeWork
383 https://doi.org/10.1038/emboj.2012.233 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049083427
384 rdf:type schema:CreativeWork
385 https://doi.org/10.1039/c2md20189e schema:sameAs https://app.dimensions.ai/details/publication/pub.1015340401
386 rdf:type schema:CreativeWork
387 https://doi.org/10.1042/bj20090928 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021145702
388 rdf:type schema:CreativeWork
389 https://doi.org/10.1042/cs20080581 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046352368
390 rdf:type schema:CreativeWork
391 https://doi.org/10.1046/j.1365-4362.2001.01083.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1007496941
392 rdf:type schema:CreativeWork
393 https://doi.org/10.1073/pnas.1108190108 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041102152
394 rdf:type schema:CreativeWork
395 https://doi.org/10.1073/pnas.1212264109 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037215264
396 rdf:type schema:CreativeWork
397 https://doi.org/10.1074/jbc.m002285200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052054996
398 rdf:type schema:CreativeWork
399 https://doi.org/10.1074/jbc.m112.359505 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043907936
400 rdf:type schema:CreativeWork
401 https://doi.org/10.1074/jbc.m112.410746 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028060443
402 rdf:type schema:CreativeWork
403 https://doi.org/10.1074/jbc.m112.413047 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012692612
404 rdf:type schema:CreativeWork
405 https://doi.org/10.1074/jbc.r700001200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050432137
406 rdf:type schema:CreativeWork
407 https://doi.org/10.1084/jem.186.1.131 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051770127
408 rdf:type schema:CreativeWork
409 https://doi.org/10.1084/jem.192.6.899 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002841485
410 rdf:type schema:CreativeWork
411 https://doi.org/10.1084/jem.193.6.713 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011193667
412 rdf:type schema:CreativeWork
413 https://doi.org/10.1093/cvr/cvr148 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021560410
414 rdf:type schema:CreativeWork
415 https://doi.org/10.1093/jmcb/mjr042 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028673905
416 rdf:type schema:CreativeWork
417 https://doi.org/10.1093/nar/gks342 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052101846
418 rdf:type schema:CreativeWork
419 https://doi.org/10.1093/nar/gks976 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027886931
420 rdf:type schema:CreativeWork
421 https://doi.org/10.1093/rheumatology/keg459 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000348279
422 rdf:type schema:CreativeWork
423 https://doi.org/10.1093/rheumatology/ken349 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036238315
424 rdf:type schema:CreativeWork
425 https://doi.org/10.1093/rheumatology/ken468 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027277171
426 rdf:type schema:CreativeWork
427 https://doi.org/10.1093/rheumatology/ken489 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047619133
428 rdf:type schema:CreativeWork
429 https://doi.org/10.1097/01.mlg.0000161334.67977.5d schema:sameAs https://app.dimensions.ai/details/publication/pub.1009886926
430 rdf:type schema:CreativeWork
431 https://doi.org/10.1111/j.0902-4441.2005.t01-1-ejh2437.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1022212451
432 rdf:type schema:CreativeWork
433 https://doi.org/10.1111/j.1346-8138.1998.tb02375.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1001138030
434 rdf:type schema:CreativeWork
435 https://doi.org/10.1111/j.1365-2141.2008.07161.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1008259678
436 rdf:type schema:CreativeWork
437 https://doi.org/10.1111/j.1365-2230.2010.03972.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1009161445
438 rdf:type schema:CreativeWork
439 https://doi.org/10.1111/j.1365-2249.2009.03947.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1007613291
440 rdf:type schema:CreativeWork
441 https://doi.org/10.1111/j.1365-2249.2010.04236.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1049628585
442 rdf:type schema:CreativeWork
443 https://doi.org/10.1111/j.1365-2249.2011.04510.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1008703005
444 rdf:type schema:CreativeWork
445 https://doi.org/10.1111/j.1365-3083.2011.02536.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1050097340
446 rdf:type schema:CreativeWork
447 https://doi.org/10.1111/j.1399-3038.2011.01198.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1015419314
448 rdf:type schema:CreativeWork
449 https://doi.org/10.1111/j.1440-1797.2010.01343.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1036626853
450 rdf:type schema:CreativeWork
451 https://doi.org/10.1111/j.1601-0825.2005.01165.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1022309784
452 rdf:type schema:CreativeWork
453 https://doi.org/10.1111/j.1755-148x.2009.00649.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1023027036
454 rdf:type schema:CreativeWork
455 https://doi.org/10.1128/jvi.00502-06 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044978788
456 rdf:type schema:CreativeWork
457 https://doi.org/10.1128/jvi.01316-08 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012491569
458 rdf:type schema:CreativeWork
459 https://doi.org/10.1128/jvi.02468-08 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010336351
460 rdf:type schema:CreativeWork
461 https://doi.org/10.1136/gut.2005.079343 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043790509
462 rdf:type schema:CreativeWork
463 https://doi.org/10.1158/1538-7445.am2012-2185 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063242705
464 rdf:type schema:CreativeWork
465 https://doi.org/10.1158/2159-8290.cd-11-0220 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039610161
466 rdf:type schema:CreativeWork
467 https://doi.org/10.1159/000237257 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036213454
468 rdf:type schema:CreativeWork
469 https://doi.org/10.1161/01.atv.15.11.1882 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063333905
470 rdf:type schema:CreativeWork
471 https://doi.org/10.1161/01.atv.19.6.1518 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013661868
472 rdf:type schema:CreativeWork
473 https://doi.org/10.1161/01.cir.0000049742.68848.99 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011078906
474 rdf:type schema:CreativeWork
475 https://doi.org/10.1161/cir.0b013e31823ac046 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051424218
476 rdf:type schema:CreativeWork
477 https://doi.org/10.1161/circulationaha.109.872903 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013624700
478 rdf:type schema:CreativeWork
479 https://doi.org/10.1167/iovs.10-6272 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047056364
480 rdf:type schema:CreativeWork
481 https://doi.org/10.1172/jci115411 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016321463
482 rdf:type schema:CreativeWork
483 https://doi.org/10.1172/jci115950 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042252284
484 rdf:type schema:CreativeWork
485 https://doi.org/10.1172/jci5624 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046321148
486 rdf:type schema:CreativeWork
487 https://doi.org/10.1177/2040620715576662 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020792420
488 rdf:type schema:CreativeWork
489 https://doi.org/10.1182/blood-2003-06-2116 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039291918
490 rdf:type schema:CreativeWork
491 https://doi.org/10.1182/blood-2008-08-172155 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031848248
492 rdf:type schema:CreativeWork
493 https://doi.org/10.1182/blood-2012-02-413021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043680109
494 rdf:type schema:CreativeWork
495 https://doi.org/10.1189/jlb.0312165 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027321056
496 rdf:type schema:CreativeWork
497 https://doi.org/10.1196/annals.1372.039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000129161
498 rdf:type schema:CreativeWork
499 https://doi.org/10.1200/jco.2005.02.8589 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020057203
500 rdf:type schema:CreativeWork
501 https://doi.org/10.1200/jco.2009.26.1347 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032892538
502 rdf:type schema:CreativeWork
503 https://doi.org/10.1210/jc.2009-1719 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064291639
504 rdf:type schema:CreativeWork
505 https://doi.org/10.1212/wnl.57.9.1561 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064380274
506 rdf:type schema:CreativeWork
507 https://doi.org/10.1242/dev.004481 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001424180
508 rdf:type schema:CreativeWork
509 https://doi.org/10.1371/journal.pone.0005903 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046254323
510 rdf:type schema:CreativeWork
511 https://doi.org/10.1371/journal.pone.0018909 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002616102
512 rdf:type schema:CreativeWork
513 https://doi.org/10.1371/journal.pone.0023656 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000155499
514 rdf:type schema:CreativeWork
515 https://doi.org/10.1371/journal.pone.0056514 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012394551
516 rdf:type schema:CreativeWork
517 https://doi.org/10.1371/journal.ppat.1002334 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043816338
518 rdf:type schema:CreativeWork
519 https://doi.org/10.1517/13543784.8.9.1327 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000394176
520 rdf:type schema:CreativeWork
521 https://doi.org/10.1517/14712598.2012.707178 schema:sameAs https://app.dimensions.ai/details/publication/pub.1067588650
522 rdf:type schema:CreativeWork
523 https://doi.org/10.1586/eci.11.7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026560618
524 rdf:type schema:CreativeWork
525 https://doi.org/10.1634/theoncologist.2010-0212 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022108823
526 rdf:type schema:CreativeWork
527 https://doi.org/10.1634/theoncologist.5-suppl_1-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031700568
528 rdf:type schema:CreativeWork
529 https://doi.org/10.1634/theoncologist.5-suppl_1-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032506924
530 rdf:type schema:CreativeWork
531 https://doi.org/10.1902/jop.2004.75.1.37 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068735047
532 rdf:type schema:CreativeWork
533 https://doi.org/10.2169/internalmedicine.32.189 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048307603
534 rdf:type schema:CreativeWork
535 https://doi.org/10.2174/156652408785160998 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069185930
536 rdf:type schema:CreativeWork
537 https://doi.org/10.2217/clp.10.37 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005849919
538 rdf:type schema:CreativeWork
539 https://doi.org/10.2340/00015555-1228 schema:sameAs https://app.dimensions.ai/details/publication/pub.1070751341
540 rdf:type schema:CreativeWork
541 https://doi.org/10.2353/ajpath.2009.090319 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005107085
542 rdf:type schema:CreativeWork
543 https://doi.org/10.3109/00207450903428970 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020096258
544 rdf:type schema:CreativeWork
545 https://doi.org/10.3109/00365513.2011.652158 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011284973
546 rdf:type schema:CreativeWork
547 https://doi.org/10.3892/ol.2012.695 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071525638
548 rdf:type schema:CreativeWork
549 https://doi.org/10.3899/jrheum.100293 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071542223
550 rdf:type schema:CreativeWork
551 https://doi.org/10.4161/cbt.4.3.1497 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072293677
552 rdf:type schema:CreativeWork
553 https://doi.org/10.4161/cc.8.17.9416 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072300237
554 rdf:type schema:CreativeWork
555 https://doi.org/10.4161/epi.5.2.10942 schema:sameAs https://app.dimensions.ai/details/publication/pub.1072302979
556 rdf:type schema:CreativeWork
 




Preview window. Press ESC to close (or click here)


...