Compositions and methods for detecting and treating colorectal cancer


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

Weiping Zou , Ilona Kryczek

ABSTRACT

The present invention relates to compositions and methods for the detecting, treating, and empirically investigating the interaction between a subject's immune system and cancer stem cells. In particular, the present invention provides compositions and methods for using IL-22 cytokine signaling and/or downstream targets of IL-22 cytokine signaling (e.g., STAT3, DOT1L, SUZ12, EED) in the diagnosis, treatment, and empirical investigation of cancers characterized with cancer stem cells activated through IL-22 cytokine signaling. More... »

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