Materials presenting notch signaling molecules to control cell behavior


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

Lan Cao , Kamal H. Bouhadir , David J. Mooney

ABSTRACT

The invention provides a solution to the problem of delivering molecules in a physiologically relevant manner to direct cell fate. For example, a Notch ligand molecule is presented in a microenvironment that mimics the environment encountered in vivo. Accordingly, the invention features a cell delivery vehicle comprising a biocompatible hydrogel or polymer and a composition that binds to a Notch receptor and methods of directing cell fate, e.g., stem cell differentiation, using such compositions. More... »

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