Compositions and methods for determining whether a subject would benefit from co-receptor inhibitor therapy


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

Wei Huang , Signe Fransen , Christos Petropoulos , Jonathan Toma , Jeannette Whitcomb

ABSTRACT

The present invention provides methods and compositions for determining whether a subject would benefit from co-receptor inhibitor therapy. In certain aspects, the methods can be used to determine whether a subject infected with a dual-mixed tropic population of HIV would benefit from CCCR5-inhibitor therapy or CXCR4-inhibitor therapy, the methods comprising determining whether the HIV population is a homogeneous or heterogeneous population of HIV, wherein the nature of the homogenous or heterogenous population of HIV indicates whether the patient would benefit from co-receptor inhibitor therapy. More... »

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