Oral therapy of necrotizing enterocolitis


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

David J. Hackam

ABSTRACT

The present invention relates to methods of treating or reducing the risk of necrotizing enterocolitis (NEC) in an infant comprising orally administering an effective amount of a CpG-ODN. It is based, at least in part, on the results of experiments in which orally administered CpG-ODNs were observed to reduce the histopathology and markers of inflammation in a murine model for NEC. The present invention further provides for oral formulations of CpG-ODN for administration to infants. More... »

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