Methods of selecting biologic-producing cell lines by next generation sequencing


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

Junjian Liu , Dean Regier , Sheng Zhang , Gerald Carson , David Ouellette

ABSTRACT

An optimized multi-step cell line screening method based on next generation sequencing (NGS) and mass spec (MS) is disclosed. The method helps reduce variants in the biologic-producing cell line and improve the efficiency of cell line development process.

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