Method of making induced pluripotent stem cells


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

Shinya Yamanaka , Keisuke Okita

ABSTRACT

A method of producing an induced pluripotent stem cell includes introducing into a somatic cell one or more non-viral expression vectors. The vectors include one or more of an Oct family gene, a Klf family gene, a Sox family gene, a Myc family gene, a Lin family gene, and Nanog gene. The somatic cell is then cultured in a medium that supports pluripotent stem cells. At least a portion of the one or more introduced non-viral expression vectors is not substantially integrated in the chromosome. More... »

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