Method of making a microbead array with attached biomolecules


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

Michael Seul

ABSTRACT

A method and apparatus for the manipulation of colloidal particulates and biomolecules at the interface between an insulating electrode such as silicon oxide and an electrolyte solution. Light-controlled electrokinetic assembly of particles near surfaces relics on the combination of three functional elements: the AC electric field-induced assembly of planar aggregates; the patterning of the electrolyte/silicon oxide/silicon interface to exert spatial control over the assembly process; and the real-time control of the assembly process via external illumination. The present invention provides a set of fundamental operations enabling interactive control over the creation and placement of planar arrays of several types of particles and biomolecules and the manipulation of array shape and size. The present invention enables sample preparation and handling for diagnostic assays and biochemical analysis in an array format, and the functional integration of these operations. In addition, the present invention provides a procedure for the creation of material surfaces with desired properties and for the fabrication of surface-mounted optical components. More... »

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    A method and apparatus for the manipulation of colloidal particulates and biomolecules at the interface between an insulating electrode such as silicon oxide and an electrolyte solution. Light-controlled electrokinetic assembly of particles near surfaces relics on the combination of three functional elements: the AC electric field-induced assembly of planar aggregates; the patterning of the electrolyte/silicon oxide/silicon interface to exert spatial control over the assembly process; and the real-time control of the assembly process via external illumination. The present invention provides a set of fundamental operations enabling interactive control over the creation and placement of planar arrays of several types of particles and biomolecules and the manipulation of array shape and size. The present invention enables sample preparation and handling for diagnostic assays and biochemical analysis in an array format, and the functional integration of these operations. In addition, the present invention provides a procedure for the creation of material surfaces with desired properties and for the fabrication of surface-mounted optical components.

    ", "id": "sg:patent.US-9400259-B2", "keywords": [ "method", "array", "biomolecules", "apparatus", "manipulation", "particulate", "interface", "electrode", "silicon oxide", "electrolyte solution", "electrokinetics", "particle", "surface", "functional element", "electric field", "aggregate", "patterning", "spatial control", "assembly process", "real-time control", "invention", "fundamental operation", "interactive control", "creation", "placement", "planar array", "sample preparation", "handling", "diagnostic assay", "biochemical analysis", "array format", "functional integration", "operation", "material surface", "desired property", "fabrication", "component" ], "name": "Method of making a microbead array with attached biomolecules", "sameAs": [ "https://app.dimensions.ai/details/patent/US-9400259-B2" ], "sdDataset": "patents", "sdDatePublished": "2019-03-07T15:32", "sdLicense": "https://scigraph.springernature.com/explorer/license/", "sdPublisher": { "name": "Springer Nature - SN SciGraph project", "type": "Organization" }, "sdSource": "s3://com.uberresearch.data.dev.patents-pipeline/full_run_10/sn-export/5eb3e5a348d7f117b22cc85fb0b02730/0000100128-0000348334/json_export_2d2c25e7.jsonl", "type": "Patent" } ]
     

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