Nonlinear optical detection of molecules comprising an unnatural amino acid possessing a hyperpolarizability


Ontology type: sgo:Patent     


Patent Info

DATE

2015-11-10T00:00

AUTHORS

SALAFSKY JOSHUA S

ABSTRACT

A system for making molecules, and proteins in particular, suitable for detection by a surface-selective nonlinear optical technique. A first use of the invention is for determining a protein's structure in real space and real time. A second use of the invention is to detect a protein or its activity (conformational change). A third use of the invention is for drug screening. A further aspect of the present invention is measuring probe tilt angle orientation in an oriented protein. More... »

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