Identification of 5-methyl-C in nucleic acid templates


Ontology type: sgo:Patent     


Patent Info

DATE

2015-11-03T00:00

AUTHORS

KORLACH JONAS , HE CHUAN , CLARK TYSON A , ZHANG LIANG , LU XINGYU

ABSTRACT

A method for identifying a 5-MeC in a template nucleic is provided. The method comprises providing a template having 5-MeC, converting the 5-MeC into a further modification selected from 5-caC and 5-FC. The converted template is then sequenced, and a change in sequencing is detected that is indicative of the further modification, allowing for identifying the 5-MeC in the template nucleic acid. More... »

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