Methods for improving multiple protein properties


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

Luis G. Cascao-Pereira , David A. Estell , James T. Kellis , Ayrookaran J. Poulose

ABSTRACT

The present invention provides efficient methods for obtaining a protein with one or more beneficial attributes in industrial, consumer or pharmaceutical applications. In some preferred embodiments, the present invention provides methods for producing superior enzymes for a given application through screening an abbreviated set of candidate enzymes.

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/2581", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "name": "Luis G. Cascao-Pereira", 
        "type": "Person"
      }, 
      {
        "name": "David A. Estell", 
        "type": "Person"
      }, 
      {
        "name": "James T. Kellis", 
        "type": "Person"
      }, 
      {
        "name": "Ayrookaran J. Poulose", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1007/s007920100198", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000734447", 
          "https://doi.org/10.1007/s007920100198"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2836(82)90515-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001452096"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/228227a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001641086", 
          "https://doi.org/10.1038/228227a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aem.71.9.5290-5296.2005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001932910"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.92.2.452", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002784539"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0888-7543(89)90280-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004053545"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.copbio.2005.06.004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004640885"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.micres.2006.06.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004680460"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/prot.340020207", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005445274"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0958-1669(97)80062-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006800050"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2836(76)90191-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007895047"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0003-9861(92)90692-p", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008379489"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4838(86)90295-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008635759"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bioeng.2005.06.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008949774"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0378-1119(83)90022-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1009757487"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/7939", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013126970", 
          "https://doi.org/10.1038/7939"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0022-2836(05)80360-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013618994"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/12.1part1.387", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014156399"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1529/biophysj.106.081547", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015192138"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0167-7799(02)02046-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015354737"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s00253-002-0975-y", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017716798", 
          "https://doi.org/10.1007/s00253-002-0975-y"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0006-3495(85)83877-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017750667"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.tibtech.2005.03.005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018088096"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/protein/gzh019", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018769646"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0003-9861(74)90352-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020849968"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2836(70)90057-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021169618"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/316774a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022183201", 
          "https://doi.org/10.1038/316774a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nbt0898-785", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022190161", 
          "https://doi.org/10.1038/nbt0898-785"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1107/s0907444994001216", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022343738"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0168-1656(93)90125-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022494686"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02603120", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022962956", 
          "https://doi.org/10.1007/bf02603120"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.69.10.3038", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023162180"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bit.21292", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024850954"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1385/abab:105:1-3:69", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025568632", 
          "https://doi.org/10.1385/abab:105:1-3:69"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.0403255101", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026887299"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.90.12.5873", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027403670"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/275673a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027410615", 
          "https://doi.org/10.1038/275673a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0020-711x(71)90023-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027811756"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/277491a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027892319", 
          "https://doi.org/10.1038/277491a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m200807200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031983937"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0958-1669(99)80071-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033010600"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/328496a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033580843", 
          "https://doi.org/10.1038/328496a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s004390050904", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035082076", 
          "https://doi.org/10.1007/s004390050904"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/s004390050904", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035082076", 
          "https://doi.org/10.1007/s004390050904"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.85.8.2444", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035928070"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.ge.23.120189.001445", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036074044"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jp0139484", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039103053"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/jmbi.1999.3034", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039238599"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0141-8130(00)00162-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040633573"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/bbrc.1998.8301", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041913449"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nprot.2007.72", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043615282", 
          "https://doi.org/10.1038/nprot.2007.72"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0003-2697(91)90045-u", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044162393"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0378-1119(77)90000-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044383550"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2836(84)90309-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044892620"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0168-1656(01)00240-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045272300"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0958-1669(00)00232-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045574673"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2836(87)90360-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1046966310"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0167-7799(01)01869-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047704793"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/mcb.8.3.1247", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048134605"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0958-1669(00)00107-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049908295"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0958-1669(02)00328-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050154064"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0022-2836(88)90540-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1050258895"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0196-8858(81)90046-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051747113"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.copbio.2006.10.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051841624"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0959-440x(00)00106-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051923464"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0167-7799(97)01138-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052250962"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/protein/gzl034", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052424595"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00152a011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055162829"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00367a013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055172250"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi047806m", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055198741"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi0600143", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055201643"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/je0603123", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055881559"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/la048459k", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056147568"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/ma00145a039", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056179974"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/bioinformatics/5.2.151", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1059413859"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.4023714", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062623786"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "description": "

The present invention provides efficient methods for obtaining a protein with one or more beneficial attributes in industrial, consumer or pharmaceutical applications. In some preferred embodiments, the present invention provides methods for producing superior enzymes for a given application through screening an abbreviated set of candidate enzymes.

", "id": "sg:patent.US-9133425-B2", "keywords": [ "method", "multiple protein", "invention", "efficient method", "protein", "attribute", "consumer", "pharmaceutical application", "embodiment", "enzyme", "given application", "Mass Screening", "candidate enzyme" ], "name": "Methods for improving multiple protein properties", "recipient": [ { "id": "https://www.grid.ac/institutes/grid.471252.7", "type": "Organization" }, { "id": "https://www.grid.ac/institutes/grid.416832.a", "type": "Organization" } ], "sameAs": [ "https://app.dimensions.ai/details/patent/US-9133425-B2" ], "sdDataset": "patents", "sdDatePublished": "2019-03-07T15:31", "sdLicense": "https://scigraph.springernature.com/explorer/license/", "sdPublisher": { "name": "Springer Nature - SN SciGraph project", "type": "Organization" }, "sdSource": "s3://com.uberresearch.data.dev.patents-pipeline/full_run_10/sn-export/5eb3e5a348d7f117b22cc85fb0b02730/0000100128-0000348334/json_export_0db08f31.jsonl", "type": "Patent" } ]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/patent.US-9133425-B2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/patent.US-9133425-B2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/patent.US-9133425-B2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/patent.US-9133425-B2'


 

This table displays all metadata directly associated to this object as RDF triples.

286 TRIPLES      14 PREDICATES      102 URIs      20 LITERALS      2 BLANK NODES

Subject Predicate Object
1 sg:patent.US-9133425-B2 schema:about anzsrc-for:2581
2 schema:author N271cbeca0bef4838944910df090abb75
3 schema:citation sg:pub.10.1007/bf02603120
4 sg:pub.10.1007/s00253-002-0975-y
5 sg:pub.10.1007/s004390050904
6 sg:pub.10.1007/s007920100198
7 sg:pub.10.1038/228227a0
8 sg:pub.10.1038/275673a0
9 sg:pub.10.1038/277491a0
10 sg:pub.10.1038/316774a0
11 sg:pub.10.1038/328496a0
12 sg:pub.10.1038/7939
13 sg:pub.10.1038/nbt0898-785
14 sg:pub.10.1038/nprot.2007.72
15 sg:pub.10.1385/abab:105:1-3:69
16 https://doi.org/10.1002/bit.21292
17 https://doi.org/10.1002/prot.340020207
18 https://doi.org/10.1006/bbrc.1998.8301
19 https://doi.org/10.1006/jmbi.1999.3034
20 https://doi.org/10.1016/0003-2697(91)90045-u
21 https://doi.org/10.1016/0003-9861(74)90352-x
22 https://doi.org/10.1016/0003-9861(92)90692-p
23 https://doi.org/10.1016/0020-711x(71)90023-1
24 https://doi.org/10.1016/0022-2836(70)90057-4
25 https://doi.org/10.1016/0022-2836(76)90191-1
26 https://doi.org/10.1016/0022-2836(82)90515-0
27 https://doi.org/10.1016/0022-2836(84)90309-7
28 https://doi.org/10.1016/0022-2836(87)90360-3
29 https://doi.org/10.1016/0022-2836(88)90540-2
30 https://doi.org/10.1016/0167-4838(86)90295-5
31 https://doi.org/10.1016/0168-1656(93)90125-7
32 https://doi.org/10.1016/0196-8858(81)90046-4
33 https://doi.org/10.1016/0378-1119(77)90000-2
34 https://doi.org/10.1016/0378-1119(83)90022-7
35 https://doi.org/10.1016/0888-7543(89)90280-2
36 https://doi.org/10.1016/j.bioeng.2005.06.001
37 https://doi.org/10.1016/j.copbio.2005.06.004
38 https://doi.org/10.1016/j.copbio.2006.10.001
39 https://doi.org/10.1016/j.micres.2006.06.001
40 https://doi.org/10.1016/j.tibtech.2005.03.005
41 https://doi.org/10.1016/s0006-3495(85)83877-7
42 https://doi.org/10.1016/s0022-2836(05)80360-2
43 https://doi.org/10.1016/s0141-8130(00)00162-8
44 https://doi.org/10.1016/s0167-7799(01)01869-8
45 https://doi.org/10.1016/s0167-7799(02)02046-2
46 https://doi.org/10.1016/s0167-7799(97)01138-4
47 https://doi.org/10.1016/s0168-1656(01)00240-1
48 https://doi.org/10.1016/s0958-1669(00)00107-5
49 https://doi.org/10.1016/s0958-1669(00)00232-9
50 https://doi.org/10.1016/s0958-1669(02)00328-2
51 https://doi.org/10.1016/s0958-1669(97)80062-6
52 https://doi.org/10.1016/s0958-1669(99)80071-8
53 https://doi.org/10.1016/s0959-440x(00)00106-8
54 https://doi.org/10.1021/bi00152a011
55 https://doi.org/10.1021/bi00367a013
56 https://doi.org/10.1021/bi047806m
57 https://doi.org/10.1021/bi0600143
58 https://doi.org/10.1021/je0603123
59 https://doi.org/10.1021/jp0139484
60 https://doi.org/10.1021/la048459k
61 https://doi.org/10.1021/ma00145a039
62 https://doi.org/10.1073/pnas.0403255101
63 https://doi.org/10.1073/pnas.69.10.3038
64 https://doi.org/10.1073/pnas.85.8.2444
65 https://doi.org/10.1073/pnas.90.12.5873
66 https://doi.org/10.1073/pnas.92.2.452
67 https://doi.org/10.1074/jbc.m200807200
68 https://doi.org/10.1093/bioinformatics/5.2.151
69 https://doi.org/10.1093/nar/12.1part1.387
70 https://doi.org/10.1093/protein/gzh019
71 https://doi.org/10.1093/protein/gzl034
72 https://doi.org/10.1107/s0907444994001216
73 https://doi.org/10.1126/science.4023714
74 https://doi.org/10.1128/aem.71.9.5290-5296.2005
75 https://doi.org/10.1128/mcb.8.3.1247
76 https://doi.org/10.1146/annurev.ge.23.120189.001445
77 https://doi.org/10.1529/biophysj.106.081547
78 schema:description <p id="p-0001" num="0000">The present invention provides efficient methods for obtaining a protein with one or more beneficial attributes in industrial, consumer or pharmaceutical applications. In some preferred embodiments, the present invention provides methods for producing superior enzymes for a given application through screening an abbreviated set of candidate enzymes.</p>
79 schema:keywords Mass Screening
80 attribute
81 candidate enzyme
82 consumer
83 efficient method
84 embodiment
85 enzyme
86 given application
87 invention
88 method
89 multiple protein
90 pharmaceutical application
91 protein
92 schema:name Methods for improving multiple protein properties
93 schema:recipient https://www.grid.ac/institutes/grid.416832.a
94 https://www.grid.ac/institutes/grid.471252.7
95 schema:sameAs https://app.dimensions.ai/details/patent/US-9133425-B2
96 schema:sdDatePublished 2019-03-07T15:31
97 schema:sdLicense https://scigraph.springernature.com/explorer/license/
98 schema:sdPublisher N7042a893193d4ffba29677addab0de28
99 sgo:license sg:explorer/license/
100 sgo:sdDataset patents
101 rdf:type sgo:Patent
102 N271cbeca0bef4838944910df090abb75 rdf:first Nfd128a562af948cca95ea9f58ca89934
103 rdf:rest Ndca4031364ce4fcba7730ca6ec345bec
104 N6a58c46f787a464e8258f32ee2a2752b schema:name Ayrookaran J. Poulose
105 rdf:type schema:Person
106 N7042a893193d4ffba29677addab0de28 schema:name Springer Nature - SN SciGraph project
107 rdf:type schema:Organization
108 N8f0514ac96e94f4da8500e4f15a23cfe rdf:first Nba548587c28c4c97842883eedf8f0e10
109 rdf:rest Nfe92309d702c45adb39ccd15d96e29db
110 N94845ff33d914c15adedf6f64efcffd0 schema:name David A. Estell
111 rdf:type schema:Person
112 Nba548587c28c4c97842883eedf8f0e10 schema:name James T. Kellis
113 rdf:type schema:Person
114 Ndca4031364ce4fcba7730ca6ec345bec rdf:first N94845ff33d914c15adedf6f64efcffd0
115 rdf:rest N8f0514ac96e94f4da8500e4f15a23cfe
116 Nfd128a562af948cca95ea9f58ca89934 schema:name Luis G. Cascao-Pereira
117 rdf:type schema:Person
118 Nfe92309d702c45adb39ccd15d96e29db rdf:first N6a58c46f787a464e8258f32ee2a2752b
119 rdf:rest rdf:nil
120 anzsrc-for:2581 schema:inDefinedTermSet anzsrc-for:
121 rdf:type schema:DefinedTerm
122 sg:pub.10.1007/bf02603120 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022962956
123 https://doi.org/10.1007/bf02603120
124 rdf:type schema:CreativeWork
125 sg:pub.10.1007/s00253-002-0975-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1017716798
126 https://doi.org/10.1007/s00253-002-0975-y
127 rdf:type schema:CreativeWork
128 sg:pub.10.1007/s004390050904 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035082076
129 https://doi.org/10.1007/s004390050904
130 rdf:type schema:CreativeWork
131 sg:pub.10.1007/s007920100198 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000734447
132 https://doi.org/10.1007/s007920100198
133 rdf:type schema:CreativeWork
134 sg:pub.10.1038/228227a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001641086
135 https://doi.org/10.1038/228227a0
136 rdf:type schema:CreativeWork
137 sg:pub.10.1038/275673a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027410615
138 https://doi.org/10.1038/275673a0
139 rdf:type schema:CreativeWork
140 sg:pub.10.1038/277491a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027892319
141 https://doi.org/10.1038/277491a0
142 rdf:type schema:CreativeWork
143 sg:pub.10.1038/316774a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022183201
144 https://doi.org/10.1038/316774a0
145 rdf:type schema:CreativeWork
146 sg:pub.10.1038/328496a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033580843
147 https://doi.org/10.1038/328496a0
148 rdf:type schema:CreativeWork
149 sg:pub.10.1038/7939 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013126970
150 https://doi.org/10.1038/7939
151 rdf:type schema:CreativeWork
152 sg:pub.10.1038/nbt0898-785 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022190161
153 https://doi.org/10.1038/nbt0898-785
154 rdf:type schema:CreativeWork
155 sg:pub.10.1038/nprot.2007.72 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043615282
156 https://doi.org/10.1038/nprot.2007.72
157 rdf:type schema:CreativeWork
158 sg:pub.10.1385/abab:105:1-3:69 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025568632
159 https://doi.org/10.1385/abab:105:1-3:69
160 rdf:type schema:CreativeWork
161 https://doi.org/10.1002/bit.21292 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024850954
162 rdf:type schema:CreativeWork
163 https://doi.org/10.1002/prot.340020207 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005445274
164 rdf:type schema:CreativeWork
165 https://doi.org/10.1006/bbrc.1998.8301 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041913449
166 rdf:type schema:CreativeWork
167 https://doi.org/10.1006/jmbi.1999.3034 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039238599
168 rdf:type schema:CreativeWork
169 https://doi.org/10.1016/0003-2697(91)90045-u schema:sameAs https://app.dimensions.ai/details/publication/pub.1044162393
170 rdf:type schema:CreativeWork
171 https://doi.org/10.1016/0003-9861(74)90352-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1020849968
172 rdf:type schema:CreativeWork
173 https://doi.org/10.1016/0003-9861(92)90692-p schema:sameAs https://app.dimensions.ai/details/publication/pub.1008379489
174 rdf:type schema:CreativeWork
175 https://doi.org/10.1016/0020-711x(71)90023-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027811756
176 rdf:type schema:CreativeWork
177 https://doi.org/10.1016/0022-2836(70)90057-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021169618
178 rdf:type schema:CreativeWork
179 https://doi.org/10.1016/0022-2836(76)90191-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007895047
180 rdf:type schema:CreativeWork
181 https://doi.org/10.1016/0022-2836(82)90515-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001452096
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1016/0022-2836(84)90309-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044892620
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1016/0022-2836(87)90360-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046966310
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1016/0022-2836(88)90540-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050258895
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1016/0167-4838(86)90295-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008635759
190 rdf:type schema:CreativeWork
191 https://doi.org/10.1016/0168-1656(93)90125-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022494686
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1016/0196-8858(81)90046-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051747113
194 rdf:type schema:CreativeWork
195 https://doi.org/10.1016/0378-1119(77)90000-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044383550
196 rdf:type schema:CreativeWork
197 https://doi.org/10.1016/0378-1119(83)90022-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009757487
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1016/0888-7543(89)90280-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004053545
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1016/j.bioeng.2005.06.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008949774
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1016/j.copbio.2005.06.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004640885
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1016/j.copbio.2006.10.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051841624
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1016/j.micres.2006.06.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004680460
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1016/j.tibtech.2005.03.005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018088096
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1016/s0006-3495(85)83877-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017750667
212 rdf:type schema:CreativeWork
213 https://doi.org/10.1016/s0022-2836(05)80360-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013618994
214 rdf:type schema:CreativeWork
215 https://doi.org/10.1016/s0141-8130(00)00162-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040633573
216 rdf:type schema:CreativeWork
217 https://doi.org/10.1016/s0167-7799(01)01869-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047704793
218 rdf:type schema:CreativeWork
219 https://doi.org/10.1016/s0167-7799(02)02046-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015354737
220 rdf:type schema:CreativeWork
221 https://doi.org/10.1016/s0167-7799(97)01138-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052250962
222 rdf:type schema:CreativeWork
223 https://doi.org/10.1016/s0168-1656(01)00240-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045272300
224 rdf:type schema:CreativeWork
225 https://doi.org/10.1016/s0958-1669(00)00107-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049908295
226 rdf:type schema:CreativeWork
227 https://doi.org/10.1016/s0958-1669(00)00232-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045574673
228 rdf:type schema:CreativeWork
229 https://doi.org/10.1016/s0958-1669(02)00328-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050154064
230 rdf:type schema:CreativeWork
231 https://doi.org/10.1016/s0958-1669(97)80062-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006800050
232 rdf:type schema:CreativeWork
233 https://doi.org/10.1016/s0958-1669(99)80071-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033010600
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1016/s0959-440x(00)00106-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051923464
236 rdf:type schema:CreativeWork
237 https://doi.org/10.1021/bi00152a011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055162829
238 rdf:type schema:CreativeWork
239 https://doi.org/10.1021/bi00367a013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055172250
240 rdf:type schema:CreativeWork
241 https://doi.org/10.1021/bi047806m schema:sameAs https://app.dimensions.ai/details/publication/pub.1055198741
242 rdf:type schema:CreativeWork
243 https://doi.org/10.1021/bi0600143 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055201643
244 rdf:type schema:CreativeWork
245 https://doi.org/10.1021/je0603123 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055881559
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1021/jp0139484 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039103053
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1021/la048459k schema:sameAs https://app.dimensions.ai/details/publication/pub.1056147568
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1021/ma00145a039 schema:sameAs https://app.dimensions.ai/details/publication/pub.1056179974
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1073/pnas.0403255101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026887299
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1073/pnas.69.10.3038 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023162180
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1073/pnas.85.8.2444 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035928070
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1073/pnas.90.12.5873 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027403670
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1073/pnas.92.2.452 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002784539
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1074/jbc.m200807200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031983937
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1093/bioinformatics/5.2.151 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059413859
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1093/nar/12.1part1.387 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014156399
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1093/protein/gzh019 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018769646
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1093/protein/gzl034 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052424595
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1107/s0907444994001216 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022343738
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1126/science.4023714 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062623786
276 rdf:type schema:CreativeWork
277 https://doi.org/10.1128/aem.71.9.5290-5296.2005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001932910
278 rdf:type schema:CreativeWork
279 https://doi.org/10.1128/mcb.8.3.1247 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048134605
280 rdf:type schema:CreativeWork
281 https://doi.org/10.1146/annurev.ge.23.120189.001445 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036074044
282 rdf:type schema:CreativeWork
283 https://doi.org/10.1529/biophysj.106.081547 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015192138
284 rdf:type schema:CreativeWork
285 https://www.grid.ac/institutes/grid.416832.a schema:Organization
286 https://www.grid.ac/institutes/grid.471252.7 schema:Organization
 




Preview window. Press ESC to close (or click here)


...