Parallel macromolecular delivery and biochemical/electrochemical interface to cells employing nanostructures


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

Timothy E. McKnight , Anatoli V. Melechko , Guy D. Griffin , Michael A. Guillorn , Vladimir L. Merkulov , Michael L. Simpson

ABSTRACT

Systems and methods are described for parallel macromolecular delivery and biochemical/electrochemical interface to whole cells employing carbon nanostructures including nanofibers and nanotubes. A method includes providing a first material on at least a first portion of a first surface of a first tip of a first elongated carbon nanostructure; providing a second material on at least a second portion of a second surface of a second tip of a second elongated carbon nanostructure, the second elongated carbon nanostructure coupled to, and substantially parallel to, the first elongated carbon nanostructure; and penetrating a boundary of a biological sample with at least one member selected from the group consisting of the first tip and the second tip. More... »

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/2447", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "name": "Timothy E. McKnight", 
        "type": "Person"
      }, 
      {
        "name": "Anatoli V. Melechko", 
        "type": "Person"
      }, 
      {
        "name": "Guy D. Griffin", 
        "type": "Person"
      }, 
      {
        "name": "Michael A. Guillorn", 
        "type": "Person"
      }, 
      {
        "name": "Vladimir L. Merkulov", 
        "type": "Person"
      }, 
      {
        "name": "Michael L. Simpson", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/35002131", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1002786107", 
          "https://doi.org/10.1038/35002131"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1067407", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004364700"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.281.5385.2016", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006510768"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0167-7799(01)01691-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008495994"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35075114", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1011603691", 
          "https://doi.org/10.1038/35075114"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/71889", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012504598", 
          "https://doi.org/10.1038/71889"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1088/0957-4484/13/5/311", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015248512"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/jmg.5.1.73", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015560011"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1077194", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015841885"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35002125", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016534270", 
          "https://doi.org/10.1038/35002125"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.bioeng.2.1.289", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1017396754"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0038-1101(01)00036-3", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018308762"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.281.5385.2013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018609686"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s1389-0344(00)00063-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021174093"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nature01257", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022279877", 
          "https://doi.org/10.1038/nature01257"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/12902", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023133375", 
          "https://doi.org/10.1038/12902"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0304-3991(91)90160-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024780523"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/nl025689f", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025123264"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/carcin/18.3.569", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028085485"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.172520999", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032473936"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0378-5173(97)00423-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1033579978"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/77760", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035209552", 
          "https://doi.org/10.1038/77760"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/415152a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1042558633", 
          "https://doi.org/10.1038/415152a"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1063/1.124650", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057688784"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1063/1.126705", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057690807"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1063/1.1395517", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057702479"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1063/1.1415411", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057704369"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1063/1.1433905", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057706427"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1063/1.1448671", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057707456"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.282.5391.1105", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062563110"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.286.5447.2148", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062567615"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "description": "

Systems and methods are described for parallel macromolecular delivery and biochemical/electrochemical interface to whole cells employing carbon nanostructures including nanofibers and nanotubes. A method includes providing a first material on at least a first portion of a first surface of a first tip of a first elongated carbon nanostructure; providing a second material on at least a second portion of a second surface of a second tip of a second elongated carbon nanostructure, the second elongated carbon nanostructure coupled to, and substantially parallel to, the first elongated carbon nanostructure; and penetrating a boundary of a biological sample with at least one member selected from the group consisting of the first tip and the second tip.

", "id": "sg:patent.US-8993327-B2", "keywords": [ "Macromolecular", "interface", "cell", "Nanostructures", "method", "carbon nanostructures", "nanofibers", "nanotube", "first portion", "surface", "tip", "second portion", "parallel", "boundary", "biological sample" ], "name": "Parallel macromolecular delivery and biochemical/electrochemical interface to cells employing nanostructures", "recipient": [ { "id": "https://www.grid.ac/institutes/grid.422038.f", "type": "Organization" } ], "sameAs": [ "https://app.dimensions.ai/details/patent/US-8993327-B2" ], "sdDataset": "patents", "sdDatePublished": "2019-03-07T15:36", "sdLicense": "https://scigraph.springernature.com/explorer/license/", "sdPublisher": { "name": "Springer Nature - SN SciGraph project", "type": "Organization" }, "sdSource": "s3://com.uberresearch.data.dev.patents-pipeline/full_run_10/sn-export/5eb3e5a348d7f117b22cc85fb0b02730/0000100128-0000348334/json_export_c290c18d.jsonl", "type": "Patent" } ]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/patent.US-8993327-B2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/patent.US-8993327-B2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/patent.US-8993327-B2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/patent.US-8993327-B2'


 

This table displays all metadata directly associated to this object as RDF triples.

157 TRIPLES      14 PREDICATES      59 URIs      22 LITERALS      2 BLANK NODES

Subject Predicate Object
1 sg:patent.US-8993327-B2 schema:about anzsrc-for:2447
2 schema:author Na4fbdc7adfa545bd95800e74ea04ffc1
3 schema:citation sg:pub.10.1038/12902
4 sg:pub.10.1038/35002125
5 sg:pub.10.1038/35002131
6 sg:pub.10.1038/35075114
7 sg:pub.10.1038/415152a
8 sg:pub.10.1038/71889
9 sg:pub.10.1038/77760
10 sg:pub.10.1038/nature01257
11 https://doi.org/10.1016/0304-3991(91)90160-8
12 https://doi.org/10.1016/s0038-1101(01)00036-3
13 https://doi.org/10.1016/s0167-7799(01)01691-2
14 https://doi.org/10.1016/s0378-5173(97)00423-7
15 https://doi.org/10.1016/s1389-0344(00)00063-0
16 https://doi.org/10.1021/nl025689f
17 https://doi.org/10.1063/1.124650
18 https://doi.org/10.1063/1.126705
19 https://doi.org/10.1063/1.1395517
20 https://doi.org/10.1063/1.1415411
21 https://doi.org/10.1063/1.1433905
22 https://doi.org/10.1063/1.1448671
23 https://doi.org/10.1073/pnas.172520999
24 https://doi.org/10.1088/0957-4484/13/5/311
25 https://doi.org/10.1093/carcin/18.3.569
26 https://doi.org/10.1126/science.1067407
27 https://doi.org/10.1126/science.1077194
28 https://doi.org/10.1126/science.281.5385.2013
29 https://doi.org/10.1126/science.281.5385.2016
30 https://doi.org/10.1126/science.282.5391.1105
31 https://doi.org/10.1126/science.286.5447.2148
32 https://doi.org/10.1136/jmg.5.1.73
33 https://doi.org/10.1146/annurev.bioeng.2.1.289
34 schema:description <p num="p-0001">Systems and methods are described for parallel macromolecular delivery and biochemical/electrochemical interface to whole cells employing carbon nanostructures including nanofibers and nanotubes. A method includes providing a first material on at least a first portion of a first surface of a first tip of a first elongated carbon nanostructure; providing a second material on at least a second portion of a second surface of a second tip of a second elongated carbon nanostructure, the second elongated carbon nanostructure coupled to, and substantially parallel to, the first elongated carbon nanostructure; and penetrating a boundary of a biological sample with at least one member selected from the group consisting of the first tip and the second tip.</p>
35 schema:keywords Macromolecular
36 Nanostructures
37 biological sample
38 boundary
39 carbon nanostructures
40 cell
41 first portion
42 interface
43 method
44 nanofibers
45 nanotube
46 parallel
47 second portion
48 surface
49 tip
50 schema:name Parallel macromolecular delivery and biochemical/electrochemical interface to cells employing nanostructures
51 schema:recipient https://www.grid.ac/institutes/grid.422038.f
52 schema:sameAs https://app.dimensions.ai/details/patent/US-8993327-B2
53 schema:sdDatePublished 2019-03-07T15:36
54 schema:sdLicense https://scigraph.springernature.com/explorer/license/
55 schema:sdPublisher Nf0115897d8414b76a15d161978ba07fc
56 sgo:license sg:explorer/license/
57 sgo:sdDataset patents
58 rdf:type sgo:Patent
59 N213fd97b9c0f4662b10e09cdd63b0aaa rdf:first Nb8cb1bf3fdcf4cb2b00e6c534f6b9ea0
60 rdf:rest Nfdfd57890eb14f6d8f69f387014d7343
61 N40325804eb524094b8be65f50a6c9f5c rdf:first N68db45020ee44a949acea5a676256b0e
62 rdf:rest Nac80bf44799849079723c84fe857957d
63 N41f6aad297b94026b2d1b17046c7faf5 schema:name Guy D. Griffin
64 rdf:type schema:Person
65 N68db45020ee44a949acea5a676256b0e schema:name Anatoli V. Melechko
66 rdf:type schema:Person
67 N8aa24622289443b5851d786867cf7afa schema:name Michael L. Simpson
68 rdf:type schema:Person
69 N9f84dd5acbed4a478874e869e3af5c98 schema:name Michael A. Guillorn
70 rdf:type schema:Person
71 Na3364fc97e1148b885de42acb57d611c schema:name Timothy E. McKnight
72 rdf:type schema:Person
73 Na4fbdc7adfa545bd95800e74ea04ffc1 rdf:first Na3364fc97e1148b885de42acb57d611c
74 rdf:rest N40325804eb524094b8be65f50a6c9f5c
75 Nac80bf44799849079723c84fe857957d rdf:first N41f6aad297b94026b2d1b17046c7faf5
76 rdf:rest Ne4c1a06a1c81402385f46e8525ae1b2e
77 Nb8cb1bf3fdcf4cb2b00e6c534f6b9ea0 schema:name Vladimir L. Merkulov
78 rdf:type schema:Person
79 Ne4c1a06a1c81402385f46e8525ae1b2e rdf:first N9f84dd5acbed4a478874e869e3af5c98
80 rdf:rest N213fd97b9c0f4662b10e09cdd63b0aaa
81 Nf0115897d8414b76a15d161978ba07fc schema:name Springer Nature - SN SciGraph project
82 rdf:type schema:Organization
83 Nfdfd57890eb14f6d8f69f387014d7343 rdf:first N8aa24622289443b5851d786867cf7afa
84 rdf:rest rdf:nil
85 anzsrc-for:2447 schema:inDefinedTermSet anzsrc-for:
86 rdf:type schema:DefinedTerm
87 sg:pub.10.1038/12902 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023133375
88 https://doi.org/10.1038/12902
89 rdf:type schema:CreativeWork
90 sg:pub.10.1038/35002125 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016534270
91 https://doi.org/10.1038/35002125
92 rdf:type schema:CreativeWork
93 sg:pub.10.1038/35002131 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002786107
94 https://doi.org/10.1038/35002131
95 rdf:type schema:CreativeWork
96 sg:pub.10.1038/35075114 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011603691
97 https://doi.org/10.1038/35075114
98 rdf:type schema:CreativeWork
99 sg:pub.10.1038/415152a schema:sameAs https://app.dimensions.ai/details/publication/pub.1042558633
100 https://doi.org/10.1038/415152a
101 rdf:type schema:CreativeWork
102 sg:pub.10.1038/71889 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012504598
103 https://doi.org/10.1038/71889
104 rdf:type schema:CreativeWork
105 sg:pub.10.1038/77760 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035209552
106 https://doi.org/10.1038/77760
107 rdf:type schema:CreativeWork
108 sg:pub.10.1038/nature01257 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022279877
109 https://doi.org/10.1038/nature01257
110 rdf:type schema:CreativeWork
111 https://doi.org/10.1016/0304-3991(91)90160-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024780523
112 rdf:type schema:CreativeWork
113 https://doi.org/10.1016/s0038-1101(01)00036-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018308762
114 rdf:type schema:CreativeWork
115 https://doi.org/10.1016/s0167-7799(01)01691-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008495994
116 rdf:type schema:CreativeWork
117 https://doi.org/10.1016/s0378-5173(97)00423-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033579978
118 rdf:type schema:CreativeWork
119 https://doi.org/10.1016/s1389-0344(00)00063-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021174093
120 rdf:type schema:CreativeWork
121 https://doi.org/10.1021/nl025689f schema:sameAs https://app.dimensions.ai/details/publication/pub.1025123264
122 rdf:type schema:CreativeWork
123 https://doi.org/10.1063/1.124650 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057688784
124 rdf:type schema:CreativeWork
125 https://doi.org/10.1063/1.126705 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057690807
126 rdf:type schema:CreativeWork
127 https://doi.org/10.1063/1.1395517 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057702479
128 rdf:type schema:CreativeWork
129 https://doi.org/10.1063/1.1415411 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057704369
130 rdf:type schema:CreativeWork
131 https://doi.org/10.1063/1.1433905 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057706427
132 rdf:type schema:CreativeWork
133 https://doi.org/10.1063/1.1448671 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057707456
134 rdf:type schema:CreativeWork
135 https://doi.org/10.1073/pnas.172520999 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032473936
136 rdf:type schema:CreativeWork
137 https://doi.org/10.1088/0957-4484/13/5/311 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015248512
138 rdf:type schema:CreativeWork
139 https://doi.org/10.1093/carcin/18.3.569 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028085485
140 rdf:type schema:CreativeWork
141 https://doi.org/10.1126/science.1067407 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004364700
142 rdf:type schema:CreativeWork
143 https://doi.org/10.1126/science.1077194 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015841885
144 rdf:type schema:CreativeWork
145 https://doi.org/10.1126/science.281.5385.2013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018609686
146 rdf:type schema:CreativeWork
147 https://doi.org/10.1126/science.281.5385.2016 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006510768
148 rdf:type schema:CreativeWork
149 https://doi.org/10.1126/science.282.5391.1105 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062563110
150 rdf:type schema:CreativeWork
151 https://doi.org/10.1126/science.286.5447.2148 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062567615
152 rdf:type schema:CreativeWork
153 https://doi.org/10.1136/jmg.5.1.73 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015560011
154 rdf:type schema:CreativeWork
155 https://doi.org/10.1146/annurev.bioeng.2.1.289 schema:sameAs https://app.dimensions.ai/details/publication/pub.1017396754
156 rdf:type schema:CreativeWork
157 https://www.grid.ac/institutes/grid.422038.f schema:Organization
 




Preview window. Press ESC to close (or click here)


...