Immunotoxin fusion proteins and means for expression thereof


Ontology type: sgo:Patent     


Patent Info

DATE

2015-03-24T00:00

AUTHORS

NEVILLE JR DAVID M , THOMPSON JERRY T , HU HUAIZHONG , WOO JUNG-HEE , MA SHENGLIN , HEXHAM JONATHAN MARK , DIGAN MARY ELLEN

ABSTRACT

The present invention described and shown in the specification and drawings provides novel recombinant DT-based immunotoxins, and, more specifically anti-T cell immunotoxin fusion proteins. Also provided are immunotoxins that can be expressed in bacterial, yeast, or mammalian cells. The invention also provides means for expression of the immunotoxin fusion protein. It is emphasized that this abstract is provided to comply with the rules requiring an abstract that will allow a searcher or other reader to quickly ascertain the subject matter of the technical disclosure. It is submitted with the understanding that it will not be used to interpret or limit the scope or meaning of the claims. More... »

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