Cationic bis-urea compounds as effective antimicrobial agents


Ontology type: sgo:Patent     


Patent Info

DATE

2014-12-30T00:00

AUTHORS

COADY DANIEL JOSEPH , ENGLER AMANDA CATHERINE , FUKUSHIMA KAZUKI , HEDRICK JAMES LUPTON , LIU SHAOQIONG , MAUNE HAREEM TARIQ , NELSON ALSHAKIM , PITERA JED WALTER , YANG YI YAN

ABSTRACT

A cationic bis-urea compound is disclosed of formula (1): wherein: each m is independently an integer of 0 to 4,each k is independently 0 or 1,each Z′ is a monovalent radical independently selected from the group consisting of hydroxyl (*—OH), carboxyl (*—COOH), cyano (*—CN), nitro (*—NO2), sulfonate (*—SO3−), trifluoromethyl (*—CF3), halides, amine groups, ketone groups, alkyl groups comprising 1 to 6 carbons, alkoxy groups comprising 1 to 6 carbons, thioether groups comprising 1 to 6 carbons, and combinations thereof,each L′ is independently a divalent alkylene group comprising 1 to 6 carbons, wherein a *-[-L′-]k- is a single bond when k is 0,each Y′ is independently a monovalent non-polymeric radical comprising a positive charged amine, andeach X′ is independently a negative charged counterion. More... »

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