Inhibitors of IAP


Ontology type: sgo:Patent     


Patent Info

DATE

2014-12-09T00:00

AUTHORS

John A. Flygare , Frederick Cohen , Kurt Deshayes , Michael F. T. Koehler , Lewis J. Gazzard , Lan Wang , Chudi Ndubaku

ABSTRACT

The invention provides novel inhibitors of IAP that are useful as therapeutic agents for treating malignancies where the compounds having the general formula U1-M-U2 wherein M is a linking group covalently joining R2, R3, R4 or R5 of U1 to an R2, R3, R4 or R5 group of U2; U1 and U2 have the general formula (I) and G, X1, X2, R2, R3, R3′, R4, R4′ and R5, are as described herein. More... »

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