Polypeptides that modulate the interaction between cells of the immune system


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

Guy Hermans , Peter Verheesen , Edward Dolk , Hendricus Renerus Jacobus Mattheus Hoogenboom , Michael John Scott Saunders , Johannes Joseph Wilhelmus de Haard , Renee de Bruin

ABSTRACT

The present invention relates to amino acid sequences that block the interaction between (a target on) an antigen presenting cell (APC) and (a target on) a T-cell. More particularly, the present invention relates to amino acid sequences that are directed against (as defined herein) a target on an APC (also referred to herein as “APC target”) or a target on a T-cell (also referred to herein as “T-cell target”). The invention further relates to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences. More... »

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