Processes for preparing substituted pyrimidines


Ontology type: sgo:Patent     


Patent Info

DATE

2014-07-15T00:00

AUTHORS

CHARRIER JEAN-DAMIEN , MAZZEI FRANCESCA , KAY DAVID , MILLER ANDREW

ABSTRACT

The present invention provides a facile process for the preparation of tri- and tetra—substituted pyrimidines. The process is useful for preparing inhibitors of protein kinases, especially Aurora kinase. These inhibitors are useful for treating or lessening the severity of Aurora—mediated diseases or conditions.

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