DLIN-KC2-DMA lipid nanoparticle delivery of modified polynucleotides


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

KENECHI EJEBI , Antonin de Fougerolles , Kristy M. Wood , Sayda M. Elbashir , Jason P. Schrum

ABSTRACT

The present disclosure provides, inter alia, formulation compositions comprising modified nucleic acid molecules which may encode a protein, a protein precursor, or a partially or fully processed form of the protein or a protein precursor. The formulation composition may further include a modified nucleic acid molecule and a delivery agent. The present invention further provides nucleic acids useful for encoding polypeptides capable of modulating a cell's function and/or activity. More... »

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