Bi- and polycyclic substituted isoquinoline and isoquinolinone derivatives


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

Oliver Plettenburg , Katrin LORENZ , Matthias LOEHN , Olivier DUCLOS , Sandrine BISCARRAT

ABSTRACT

The invention relates to bi- and polycyclic substituted isoquinoline and isoquinolinones of the formula (I) wherein R1 to R12 are as defined in the application useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.

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