Quinoxaline derivatives as antitumor agents


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

Robert R. Becklin , Cindy Lou Chepanoske , John M. Peltier , Longwu Qi , Paul B. Robbins , Sudhir R. Sahasrabudhe , Robert Selliah , Keith Simmon , Brent R. Stockwell , Raj Gopal Venkat , Moritz von Rechenberg , Eugene Y. Zhen

ABSTRACT

The invention relates to methods of screening for binding partners, especially binding partners essential for the biological activity of erastin (e.g. VDACs such as VDAC3). The invention also provides reagents and methods for effective killing of cancer cells with erastin and related compounds or derivatives.

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