Fusion proteins of collagen-binding domain and parathyroid hormone


Ontology type: sgo:Patent     


Patent Info

DATE

2013-05-28T00:00

AUTHORS

Joshua Sakon , Robert C. Gensure , Osamu Matsushita

ABSTRACT

Fusion proteins containing active agonist or antagonist fragments of parathyroid hormone (PTH) and parathyroid hormone related peptide (PTHrP) coupled to a collagen-binding domain are presented. The fusion proteins can be used to promote bone growth, to promote hair growth, to prevent cancer metastasis to bone, to promote immune reconstitution with a bone marrow stem cell transplant, to promote mobilization of bone marrow stem cells for collection for autologous stem cell transplant, and to treat renal osteodystrophy. Pharmaceutical agents comprising a collagen-binding polypeptide segment linked to a non-peptidyl PTH/PTHrP receptor agonist or antagonist are also presented. More... »

Related SciGraph Publications

  • 2008-06. The cell biology of parathyroid hormone in osteoblasts in CURRENT OSTEOPOROSIS REPORTS
  • 2005-03. Structural organization and biological relevance of oscillatory parathyroid hormone secretion in PEDIATRIC NEPHROLOGY
  • 2010-11. Repetition of continuous PTH treatments followed by periodic withdrawals exerts anabolic effects on rat bone in JOURNAL OF BONE AND MINERAL METABOLISM
  • 2000-01. Parathyroid hormone temporal effects on bone formation and resorption in BULLETIN OF MATHEMATICAL BIOLOGY
  • 2009-04. Differential Regulation of RGS-2 by Constant and Oscillating PTH Concentrations in CALCIFIED TISSUE INTERNATIONAL
  • 2001-11. Parathyroid Hormone in the Treatment of Osteoporosis in BIODRUGS
  • 2003-10. Osteoblastic cells regulate the haematopoietic stem cell niche in NATURE
  • 2005-08. Parathyroid Hormone Induces Receptor Activity Modifying Protein-3 (RAMP3) Expression Primarily Via 3′,5′-Cyclic Adenosine Monophosphate Signaling in Osteoblasts in CALCIFIED TISSUE INTERNATIONAL
  • 2002-02. Differential effects of intermittent and continuous administration of parathyroid hormone on bone histomorphometry and gene expression in ENDOCRINE
  • 2004-01. The use of intermittent human parathyroid hormone as a treatment for osteoporosis in CURRENT RHEUMATOLOGY REPORTS
  • 2002-04. The Anabolic Effects of Parathyroid Hormone in OSTEOPOROSIS INTERNATIONAL
  • 2007-10. Bone mineral density and bone histomorphometry in children on long-term dialysis in PEDIATRIC NEPHROLOGY
  • 1986-02. Bone mineral changes in primary hyperparathyroidism in SKELETAL RADIOLOGY
  • 1989-06. Elective total parathyroidectomy without autotransplant in end-stage renal disease in KIDNEY INTERNATIONAL
  • 2001-08. A New Strategy for Modulating Chemotherapy-Induced Alopecia, Using PTH/PTHrP Receptor Agonist and Antagonist in JOURNAL OF INVESTIGATIVE DERMATOLOGY
  • JSON-LD is the canonical representation for SciGraph data.

    TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

    [
      {
        "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
        "about": [
          {
            "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/3053", 
            "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
            "type": "DefinedTerm"
          }
        ], 
        "author": [
          {
            "name": "Joshua Sakon", 
            "type": "Person"
          }, 
          {
            "name": "Robert C. Gensure", 
            "type": "Person"
          }, 
          {
            "name": "Osamu Matsushita", 
            "type": "Person"
          }
        ], 
        "citation": [
          {
            "id": "https://doi.org/10.1097/med.0b013e32831a46d6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000183632"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/med.0b013e32831a46d6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000183632"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/med.0b013e32831a46d6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000183632"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0167-4889(94)90053-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000831929"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0167-4889(94)90053-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1000831929"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jcb.20216", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001022025"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m705194200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001188492"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1196/annals.1402.047", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1001491831"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0169-6009(91)90029-y", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002179623"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.healun.2004.03.020", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002600636"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.healun.2004.03.020", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002600636"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1159/000191200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1002825391"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bone.2006.09.008", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003255367"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature02040", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003509222", 
              "https://doi.org/10.1038/nature02040"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/nature02040", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003509222", 
              "https://doi.org/10.1038/nature02040"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/emboj/cdg172", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1003588282"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jbmr.5650070110", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004231856"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jbmr.5650070110", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004231856"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1172/jci113885", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004728605"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1359/jbmr.2000.15.1.175", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004799715"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cellsig.2009.10.017", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1004969019"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.273.6.3643", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1005703051"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.biomaterials.2006.10.013", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1006778661"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1080/00016470410004012", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007041213"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jcb.21314", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007214600"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jcb.21314", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007214600"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0303-2647(03)00040-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007769720"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0303-2647(03)00040-6", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007769720"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bone.2007.03.017", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1007854333"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jbmr.5650090807", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008221539"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jbmr.5650090807", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1008221539"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00350200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009032466", 
              "https://doi.org/10.1007/bf00350200"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/bf00350200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009032466", 
              "https://doi.org/10.1007/bf00350200"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s8756-3282(03)00057-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009160072"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s8756-3282(03)00057-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1009160072"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1749-6632.2009.05216.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010560741"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1749-6632.2009.05216.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1010560741"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jcb.21626", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011119453"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.jtbi.2004.03.023", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011358803"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1359/jbmr.2000.15.7.1412", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011457559"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.tem.2004.01.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1011974546"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1385/endo:17:1:29", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1012503521", 
              "https://doi.org/10.1385/endo:17:1:29"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1080/15419060802310208", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1013809339"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00467-007-0546-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014689430", 
              "https://doi.org/10.1007/s00467-007-0546-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00467-007-0546-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1014689430", 
              "https://doi.org/10.1007/s00467-007-0546-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jcb.10490", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015234336"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbrc.2004.11.069", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015375270"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/01.mnh.0000133984.47806.00", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015574560"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1097/01.mnh.0000133984.47806.00", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015574560"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1371/journal.pone.0012290", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015584669"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1038/ki.1989.138", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015805771", 
              "https://doi.org/10.1038/ki.1989.138"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1038/ki.1989.138", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1015805771"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1359/jbmr.050602", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016126531"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1359/jbmr.2000.15.3.550", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016601544"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1172/jci11296", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1016957718"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2174/1874192401004010110", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1018501732"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0014-5793(97)00484-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019091548"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1440-1797.2009.01257.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019608458"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1440-1797.2009.01257.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019608458"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbrc.2009.01.167", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019807620"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bone.2009.06.020", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019835628"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bone.2009.06.020", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019835628"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00223-009-9222-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019840982", 
              "https://doi.org/10.1007/s00223-009-9222-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00223-009-9222-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1019840982", 
              "https://doi.org/10.1007/s00223-009-9222-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m003450200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021435743"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00774-010-0181-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021440890", 
              "https://doi.org/10.1007/s00774-010-0181-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00774-010-0181-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021440890", 
              "https://doi.org/10.1007/s00774-010-0181-4"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1359/jbmr.1999.14.1.11", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021583507"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1677/joe.1.06057", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1021716230"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0736-0266(03)00042-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022320544"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1359/jbmr.2000.15.4.740", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1022913784"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1172/jci11777", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1023565430"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0378-1119(01)00798-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1024987111"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0026-0495(76)90024-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025535085"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11914-008-0013-9", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1025759610", 
              "https://doi.org/10.1007/s11914-008-0013-9"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2215/cjn.01961205", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1027649131"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.mehy.2008.10.015", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028158802"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.ygcen.2007.11.003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028228180"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1046/j.1525-1594.2003.07009.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1028735724"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jcb.20822", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029456735"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jcb.20822", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029456735"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0002-9610(85)80050-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1029497463"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s8756-3282(99)00263-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031081075"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.2165/00063030-200115110-00003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031484050", 
              "https://doi.org/10.2165/00063030-200115110-00003"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.2165/00063030-200115110-00003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1031484050", 
              "https://doi.org/10.2165/00063030-200115110-00003"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0736-0266(01)00157-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032261231"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00223-004-0239-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032633368", 
              "https://doi.org/10.1007/s00223-004-0239-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00223-004-0239-1", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1032633368", 
              "https://doi.org/10.1007/s00223-004-0239-1"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0026-0495(83)90149-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033057234"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bone.2005.04.011", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033181059"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3109/03008200109016842", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1033572290"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/154405910308201006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034015686"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/154405910308201006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034015686"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00467-004-1767-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034228942", 
              "https://doi.org/10.1007/s00467-004-1767-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s00467-004-1767-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034228942", 
              "https://doi.org/10.1007/s00467-004-1767-7"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1172/jci109327", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034822451"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/1087057105279952", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034870735"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/1087057105279952", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034870735"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1177/1087057105279952", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1034870735"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.cccn.2004.10.003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1035702716"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1365-2362.2006.01664.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036787136"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1046/j.0022-202x.2001.01410.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036895262", 
              "https://doi.org/10.1046/j.0022-202x.2001.01410.x"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1046/j.0022-202x.2001.01410.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036895262"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1046/j.0022-202x.2001.01410.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1036895262"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1038/sj.bjp.0703830", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037462943"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s001980200026", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1037635540", 
              "https://doi.org/10.1007/s001980200026"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1359/jbmr.2003.18.7.1235", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038041744"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1677/joe.1.06351", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038241444"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jcb.20438", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1038438657"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.m007400200", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039392495"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1006/bulm.1999.0146", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039849014", 
              "https://doi.org/10.1006/bulm.1999.0146"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bone.2010.05.006", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039864035"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1442-200x.1998.tb01407.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039881951"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1111/j.1442-200x.1998.tb01407.x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039881951"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0169-6009(08)80020-7", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1039993895"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1043-2760(97)00060-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040036140"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "sg:pub.10.1007/s11926-004-0083-3", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1040220500", 
              "https://doi.org/10.1007/s11926-004-0083-3"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1530/acta.0.1080217", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1041097968"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jcb.22124", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042264209"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bone.2008.03.024", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1042471171"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jbmr.145", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043392720"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/en.2002-220428", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1043469931"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/(sici)1097-4644(19960616)61:4<638::aid-jcb18>3.0.co;2-b", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044433046"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1152/ajpendo.00029.2005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044975767"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1152/ajpendo.00029.2005", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1044975767"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0749-0690(02)00074-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045429078"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s0026-0495(97)90284-5", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1045832587"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/s1043-2760(01)00460-x", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046293334"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/cvr/cvm080", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1046334750"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1172/jci119491", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047036818"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.mehy.2009.10.047", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1047787125"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bone.2006.06.010", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1049214667"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.abb.2008.03.003", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050612094"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1073/pnas.95.12.7018", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1050811163"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1074/jbc.271.33.19888", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051336851"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.bbrc.2005.04.132", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051452418"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/j.coph.2005.07.004", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051647392"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1016/0002-9343(87)90068-4", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1051674153"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jbmr.5650040302", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052113019"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1002/jbmr.5650040302", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1052113019"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1196/annals.1402.031", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1053237154"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1093/oxfordjournals.jbchem.a002900", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1059959577"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1128/jb.176.21.6489-6496.1994", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1062723201"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1172/jci14663", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1063415285"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/en.2002-220221", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064245769"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/en.2002-221000", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064245923"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/en.2004-1557", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064247240"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/en.2004-1642", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064247272"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/en.2005-0239", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064247371"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/endo-110-2-506", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064256184"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/endo-112-3-1000", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064257008"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2003-030470", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064286867"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2009-0233", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064291236"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2009-0233", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064291236"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.2010-1723", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064292374"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1210/jc.81.10.3584", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1064298535"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.1615/critreveukaryotgeneexpr.v13.i1.30", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1068131427"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2174/1381612013397780", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1069164545"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.2174/1381612023393387", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1069164625"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3171/foc.2001.11.2.8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071085245"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3171/foc.2001.11.2.8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071085245"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3171/foc.2001.11.2.8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071085245"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3171/foc.2001.11.2.8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071085245"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3171/foc.2001.11.2.8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071085245"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3171/foc.2001.11.2.8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071085245"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.3171/foc.2001.11.2.8", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1071085245"
            ], 
            "type": "CreativeWork"
          }, 
          {
            "id": "https://doi.org/10.5144/0256-4947.1999.110", 
            "sameAs": [
              "https://app.dimensions.ai/details/publication/pub.1077380154"
            ], 
            "type": "CreativeWork"
          }
        ], 
        "datePublished": "2013-05-28T00:00", 
        "description": "

    Fusion proteins containing active agonist or antagonist fragments of parathyroid hormone (PTH) and parathyroid hormone related peptide (PTHrP) coupled to a collagen-binding domain are presented. The fusion proteins can be used to promote bone growth, to promote hair growth, to prevent cancer metastasis to bone, to promote immune reconstitution with a bone marrow stem cell transplant, to promote mobilization of bone marrow stem cells for collection for autologous stem cell transplant, and to treat renal osteodystrophy. Pharmaceutical agents comprising a collagen-binding polypeptide segment linked to a non-peptidyl PTH/PTHrP receptor agonist or antagonist are also presented.

    ", "id": "sg:patent.US-8450273-B2", "keywords": [ "fusion protein", "collagen binding", "parathyroid hormone", "agonist", "antagonist", "Parathyroid Hormone-Related Protein", "parathyroid hormonerP", "Bone Development", "hair growth", "cancer metastasis", "Bone and Bone", "immune reconstitution", "bone marrow stem cell", "mobilization", "collection", "autologous stem cell transplant", "renal osteodystrophy", "pharmaceutical agent", "parathyroid hormone/parathyroid hormonerP receptor" ], "name": "Fusion proteins of collagen-binding domain and parathyroid hormone", "recipient": [ { "id": "https://www.grid.ac/institutes/grid.258331.e", "type": "Organization" }, { "id": "https://www.grid.ac/institutes/grid.194632.b", "type": "Organization" }, { "id": "https://www.grid.ac/institutes/grid.240416.5", "type": "Organization" } ], "sameAs": [ "https://app.dimensions.ai/details/patent/US-8450273-B2" ], "sdDataset": "patents", "sdDatePublished": "2019-04-18T10:11", "sdLicense": "https://scigraph.springernature.com/explorer/license/", "sdPublisher": { "name": "Springer Nature - SN SciGraph project", "type": "Organization" }, "sdSource": "s3://com-uberresearch-data-patents-target-20190320-rc/data/sn-export/402f166718b70575fb5d4ffe01f064d1/0000100128-0000352499/json_export_00534.jsonl", "type": "Patent" } ]
     

    Download the RDF metadata as:  json-ld nt turtle xml License info

    HOW TO GET THIS DATA PROGRAMMATICALLY:

    JSON-LD is a popular format for linked data which is fully compatible with JSON.

    curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/patent.US-8450273-B2'

    N-Triples is a line-based linked data format ideal for batch operations.

    curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/patent.US-8450273-B2'

    Turtle is a human-readable linked data format.

    curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/patent.US-8450273-B2'

    RDF/XML is a standard XML format for linked data.

    curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/patent.US-8450273-B2'


     

    This table displays all metadata directly associated to this object as RDF triples.

    461 TRIPLES      15 PREDICATES      166 URIs      27 LITERALS      2 BLANK NODES

    Subject Predicate Object
    1 sg:patent.US-8450273-B2 schema:about anzsrc-for:3053
    2 schema:author Nfde9dfec41e44dc6a3bbbaf2741e0f9c
    3 schema:citation sg:pub.10.1006/bulm.1999.0146
    4 sg:pub.10.1007/bf00350200
    5 sg:pub.10.1007/s001980200026
    6 sg:pub.10.1007/s00223-004-0239-1
    7 sg:pub.10.1007/s00223-009-9222-1
    8 sg:pub.10.1007/s00467-004-1767-7
    9 sg:pub.10.1007/s00467-007-0546-7
    10 sg:pub.10.1007/s00774-010-0181-4
    11 sg:pub.10.1007/s11914-008-0013-9
    12 sg:pub.10.1007/s11926-004-0083-3
    13 sg:pub.10.1038/ki.1989.138
    14 sg:pub.10.1038/nature02040
    15 sg:pub.10.1046/j.0022-202x.2001.01410.x
    16 sg:pub.10.1385/endo:17:1:29
    17 sg:pub.10.2165/00063030-200115110-00003
    18 https://doi.org/10.1002/(sici)1097-4644(19960616)61:4<638::aid-jcb18>3.0.co;2-b
    19 https://doi.org/10.1002/jbmr.145
    20 https://doi.org/10.1002/jbmr.5650040302
    21 https://doi.org/10.1002/jbmr.5650070110
    22 https://doi.org/10.1002/jbmr.5650090807
    23 https://doi.org/10.1002/jcb.10490
    24 https://doi.org/10.1002/jcb.20216
    25 https://doi.org/10.1002/jcb.20438
    26 https://doi.org/10.1002/jcb.20822
    27 https://doi.org/10.1002/jcb.21314
    28 https://doi.org/10.1002/jcb.21626
    29 https://doi.org/10.1002/jcb.22124
    30 https://doi.org/10.1016/0002-9343(87)90068-4
    31 https://doi.org/10.1016/0026-0495(76)90024-x
    32 https://doi.org/10.1016/0026-0495(83)90149-x
    33 https://doi.org/10.1016/0167-4889(94)90053-1
    34 https://doi.org/10.1016/0169-6009(91)90029-y
    35 https://doi.org/10.1016/j.abb.2008.03.003
    36 https://doi.org/10.1016/j.bbrc.2004.11.069
    37 https://doi.org/10.1016/j.bbrc.2005.04.132
    38 https://doi.org/10.1016/j.bbrc.2009.01.167
    39 https://doi.org/10.1016/j.biomaterials.2006.10.013
    40 https://doi.org/10.1016/j.bone.2005.04.011
    41 https://doi.org/10.1016/j.bone.2006.06.010
    42 https://doi.org/10.1016/j.bone.2006.09.008
    43 https://doi.org/10.1016/j.bone.2007.03.017
    44 https://doi.org/10.1016/j.bone.2008.03.024
    45 https://doi.org/10.1016/j.bone.2009.06.020
    46 https://doi.org/10.1016/j.bone.2010.05.006
    47 https://doi.org/10.1016/j.cccn.2004.10.003
    48 https://doi.org/10.1016/j.cellsig.2009.10.017
    49 https://doi.org/10.1016/j.coph.2005.07.004
    50 https://doi.org/10.1016/j.healun.2004.03.020
    51 https://doi.org/10.1016/j.jtbi.2004.03.023
    52 https://doi.org/10.1016/j.mehy.2008.10.015
    53 https://doi.org/10.1016/j.mehy.2009.10.047
    54 https://doi.org/10.1016/j.tem.2004.01.006
    55 https://doi.org/10.1016/j.ygcen.2007.11.003
    56 https://doi.org/10.1016/s0002-9610(85)80050-7
    57 https://doi.org/10.1016/s0014-5793(97)00484-5
    58 https://doi.org/10.1016/s0026-0495(97)90284-5
    59 https://doi.org/10.1016/s0169-6009(08)80020-7
    60 https://doi.org/10.1016/s0303-2647(03)00040-6
    61 https://doi.org/10.1016/s0378-1119(01)00798-3
    62 https://doi.org/10.1016/s0736-0266(01)00157-7
    63 https://doi.org/10.1016/s0736-0266(03)00042-1
    64 https://doi.org/10.1016/s0749-0690(02)00074-5
    65 https://doi.org/10.1016/s1043-2760(01)00460-x
    66 https://doi.org/10.1016/s1043-2760(97)00060-x
    67 https://doi.org/10.1016/s8756-3282(03)00057-7
    68 https://doi.org/10.1016/s8756-3282(99)00263-x
    69 https://doi.org/10.1038/ki.1989.138
    70 https://doi.org/10.1038/sj.bjp.0703830
    71 https://doi.org/10.1046/j.0022-202x.2001.01410.x
    72 https://doi.org/10.1046/j.1525-1594.2003.07009.x
    73 https://doi.org/10.1073/pnas.95.12.7018
    74 https://doi.org/10.1074/jbc.271.33.19888
    75 https://doi.org/10.1074/jbc.273.6.3643
    76 https://doi.org/10.1074/jbc.m003450200
    77 https://doi.org/10.1074/jbc.m007400200
    78 https://doi.org/10.1074/jbc.m705194200
    79 https://doi.org/10.1080/00016470410004012
    80 https://doi.org/10.1080/15419060802310208
    81 https://doi.org/10.1093/cvr/cvm080
    82 https://doi.org/10.1093/emboj/cdg172
    83 https://doi.org/10.1093/oxfordjournals.jbchem.a002900
    84 https://doi.org/10.1097/01.mnh.0000133984.47806.00
    85 https://doi.org/10.1097/med.0b013e32831a46d6
    86 https://doi.org/10.1111/j.1365-2362.2006.01664.x
    87 https://doi.org/10.1111/j.1440-1797.2009.01257.x
    88 https://doi.org/10.1111/j.1442-200x.1998.tb01407.x
    89 https://doi.org/10.1111/j.1749-6632.2009.05216.x
    90 https://doi.org/10.1128/jb.176.21.6489-6496.1994
    91 https://doi.org/10.1152/ajpendo.00029.2005
    92 https://doi.org/10.1159/000191200
    93 https://doi.org/10.1172/jci109327
    94 https://doi.org/10.1172/jci11296
    95 https://doi.org/10.1172/jci113885
    96 https://doi.org/10.1172/jci11777
    97 https://doi.org/10.1172/jci119491
    98 https://doi.org/10.1172/jci14663
    99 https://doi.org/10.1177/1087057105279952
    100 https://doi.org/10.1177/154405910308201006
    101 https://doi.org/10.1196/annals.1402.031
    102 https://doi.org/10.1196/annals.1402.047
    103 https://doi.org/10.1210/en.2002-220221
    104 https://doi.org/10.1210/en.2002-220428
    105 https://doi.org/10.1210/en.2002-221000
    106 https://doi.org/10.1210/en.2004-1557
    107 https://doi.org/10.1210/en.2004-1642
    108 https://doi.org/10.1210/en.2005-0239
    109 https://doi.org/10.1210/endo-110-2-506
    110 https://doi.org/10.1210/endo-112-3-1000
    111 https://doi.org/10.1210/jc.2003-030470
    112 https://doi.org/10.1210/jc.2009-0233
    113 https://doi.org/10.1210/jc.2010-1723
    114 https://doi.org/10.1210/jc.81.10.3584
    115 https://doi.org/10.1359/jbmr.050602
    116 https://doi.org/10.1359/jbmr.1999.14.1.11
    117 https://doi.org/10.1359/jbmr.2000.15.1.175
    118 https://doi.org/10.1359/jbmr.2000.15.3.550
    119 https://doi.org/10.1359/jbmr.2000.15.4.740
    120 https://doi.org/10.1359/jbmr.2000.15.7.1412
    121 https://doi.org/10.1359/jbmr.2003.18.7.1235
    122 https://doi.org/10.1371/journal.pone.0012290
    123 https://doi.org/10.1530/acta.0.1080217
    124 https://doi.org/10.1615/critreveukaryotgeneexpr.v13.i1.30
    125 https://doi.org/10.1677/joe.1.06057
    126 https://doi.org/10.1677/joe.1.06351
    127 https://doi.org/10.2174/1381612013397780
    128 https://doi.org/10.2174/1381612023393387
    129 https://doi.org/10.2174/1874192401004010110
    130 https://doi.org/10.2215/cjn.01961205
    131 https://doi.org/10.3109/03008200109016842
    132 https://doi.org/10.3171/foc.2001.11.2.8
    133 https://doi.org/10.5144/0256-4947.1999.110
    134 schema:datePublished 2013-05-28T00:00
    135 schema:description <p num="p-0001">Fusion proteins containing active agonist or antagonist fragments of parathyroid hormone (PTH) and parathyroid hormone related peptide (PTHrP) coupled to a collagen-binding domain are presented. The fusion proteins can be used to promote bone growth, to promote hair growth, to prevent cancer metastasis to bone, to promote immune reconstitution with a bone marrow stem cell transplant, to promote mobilization of bone marrow stem cells for collection for autologous stem cell transplant, and to treat renal osteodystrophy. Pharmaceutical agents comprising a collagen-binding polypeptide segment linked to a non-peptidyl PTH/PTHrP receptor agonist or antagonist are also presented.</p>
    136 schema:keywords Bone Development
    137 Bone and Bone
    138 Parathyroid Hormone-Related Protein
    139 agonist
    140 antagonist
    141 autologous stem cell transplant
    142 bone marrow stem cell
    143 cancer metastasis
    144 collagen binding
    145 collection
    146 fusion protein
    147 hair growth
    148 immune reconstitution
    149 mobilization
    150 parathyroid hormone
    151 parathyroid hormone/parathyroid hormonerP receptor
    152 parathyroid hormonerP
    153 pharmaceutical agent
    154 renal osteodystrophy
    155 schema:name Fusion proteins of collagen-binding domain and parathyroid hormone
    156 schema:recipient https://www.grid.ac/institutes/grid.194632.b
    157 https://www.grid.ac/institutes/grid.240416.5
    158 https://www.grid.ac/institutes/grid.258331.e
    159 schema:sameAs https://app.dimensions.ai/details/patent/US-8450273-B2
    160 schema:sdDatePublished 2019-04-18T10:11
    161 schema:sdLicense https://scigraph.springernature.com/explorer/license/
    162 schema:sdPublisher Na6990b94d9854702b3606b0c535a2df1
    163 sgo:license sg:explorer/license/
    164 sgo:sdDataset patents
    165 rdf:type sgo:Patent
    166 N19fc8c7131574ff090e65954a36fe4fe schema:name Osamu Matsushita
    167 rdf:type schema:Person
    168 N7a50e16fd8d545cd99636f3e44aff3e0 rdf:first N7d2d3759a78e4e37ae2b7707a4b142d7
    169 rdf:rest N9f3ee2e5000f4a338e85bb753e65ec72
    170 N7d2d3759a78e4e37ae2b7707a4b142d7 schema:name Robert C. Gensure
    171 rdf:type schema:Person
    172 N9f3ee2e5000f4a338e85bb753e65ec72 rdf:first N19fc8c7131574ff090e65954a36fe4fe
    173 rdf:rest rdf:nil
    174 N9fdc01c6d8e14ed2843ef57fb69cf3c8 schema:name Joshua Sakon
    175 rdf:type schema:Person
    176 Na6990b94d9854702b3606b0c535a2df1 schema:name Springer Nature - SN SciGraph project
    177 rdf:type schema:Organization
    178 Nfde9dfec41e44dc6a3bbbaf2741e0f9c rdf:first N9fdc01c6d8e14ed2843ef57fb69cf3c8
    179 rdf:rest N7a50e16fd8d545cd99636f3e44aff3e0
    180 anzsrc-for:3053 schema:inDefinedTermSet anzsrc-for:
    181 rdf:type schema:DefinedTerm
    182 sg:pub.10.1006/bulm.1999.0146 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039849014
    183 https://doi.org/10.1006/bulm.1999.0146
    184 rdf:type schema:CreativeWork
    185 sg:pub.10.1007/bf00350200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009032466
    186 https://doi.org/10.1007/bf00350200
    187 rdf:type schema:CreativeWork
    188 sg:pub.10.1007/s001980200026 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037635540
    189 https://doi.org/10.1007/s001980200026
    190 rdf:type schema:CreativeWork
    191 sg:pub.10.1007/s00223-004-0239-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032633368
    192 https://doi.org/10.1007/s00223-004-0239-1
    193 rdf:type schema:CreativeWork
    194 sg:pub.10.1007/s00223-009-9222-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019840982
    195 https://doi.org/10.1007/s00223-009-9222-1
    196 rdf:type schema:CreativeWork
    197 sg:pub.10.1007/s00467-004-1767-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034228942
    198 https://doi.org/10.1007/s00467-004-1767-7
    199 rdf:type schema:CreativeWork
    200 sg:pub.10.1007/s00467-007-0546-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014689430
    201 https://doi.org/10.1007/s00467-007-0546-7
    202 rdf:type schema:CreativeWork
    203 sg:pub.10.1007/s00774-010-0181-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021440890
    204 https://doi.org/10.1007/s00774-010-0181-4
    205 rdf:type schema:CreativeWork
    206 sg:pub.10.1007/s11914-008-0013-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025759610
    207 https://doi.org/10.1007/s11914-008-0013-9
    208 rdf:type schema:CreativeWork
    209 sg:pub.10.1007/s11926-004-0083-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040220500
    210 https://doi.org/10.1007/s11926-004-0083-3
    211 rdf:type schema:CreativeWork
    212 sg:pub.10.1038/ki.1989.138 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015805771
    213 https://doi.org/10.1038/ki.1989.138
    214 rdf:type schema:CreativeWork
    215 sg:pub.10.1038/nature02040 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003509222
    216 https://doi.org/10.1038/nature02040
    217 rdf:type schema:CreativeWork
    218 sg:pub.10.1046/j.0022-202x.2001.01410.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1036895262
    219 https://doi.org/10.1046/j.0022-202x.2001.01410.x
    220 rdf:type schema:CreativeWork
    221 sg:pub.10.1385/endo:17:1:29 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012503521
    222 https://doi.org/10.1385/endo:17:1:29
    223 rdf:type schema:CreativeWork
    224 sg:pub.10.2165/00063030-200115110-00003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031484050
    225 https://doi.org/10.2165/00063030-200115110-00003
    226 rdf:type schema:CreativeWork
    227 https://doi.org/10.1002/(sici)1097-4644(19960616)61:4<638::aid-jcb18>3.0.co;2-b schema:sameAs https://app.dimensions.ai/details/publication/pub.1044433046
    228 rdf:type schema:CreativeWork
    229 https://doi.org/10.1002/jbmr.145 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043392720
    230 rdf:type schema:CreativeWork
    231 https://doi.org/10.1002/jbmr.5650040302 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052113019
    232 rdf:type schema:CreativeWork
    233 https://doi.org/10.1002/jbmr.5650070110 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004231856
    234 rdf:type schema:CreativeWork
    235 https://doi.org/10.1002/jbmr.5650090807 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008221539
    236 rdf:type schema:CreativeWork
    237 https://doi.org/10.1002/jcb.10490 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015234336
    238 rdf:type schema:CreativeWork
    239 https://doi.org/10.1002/jcb.20216 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001022025
    240 rdf:type schema:CreativeWork
    241 https://doi.org/10.1002/jcb.20438 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038438657
    242 rdf:type schema:CreativeWork
    243 https://doi.org/10.1002/jcb.20822 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029456735
    244 rdf:type schema:CreativeWork
    245 https://doi.org/10.1002/jcb.21314 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007214600
    246 rdf:type schema:CreativeWork
    247 https://doi.org/10.1002/jcb.21626 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011119453
    248 rdf:type schema:CreativeWork
    249 https://doi.org/10.1002/jcb.22124 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042264209
    250 rdf:type schema:CreativeWork
    251 https://doi.org/10.1016/0002-9343(87)90068-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051674153
    252 rdf:type schema:CreativeWork
    253 https://doi.org/10.1016/0026-0495(76)90024-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1025535085
    254 rdf:type schema:CreativeWork
    255 https://doi.org/10.1016/0026-0495(83)90149-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1033057234
    256 rdf:type schema:CreativeWork
    257 https://doi.org/10.1016/0167-4889(94)90053-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000831929
    258 rdf:type schema:CreativeWork
    259 https://doi.org/10.1016/0169-6009(91)90029-y schema:sameAs https://app.dimensions.ai/details/publication/pub.1002179623
    260 rdf:type schema:CreativeWork
    261 https://doi.org/10.1016/j.abb.2008.03.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050612094
    262 rdf:type schema:CreativeWork
    263 https://doi.org/10.1016/j.bbrc.2004.11.069 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015375270
    264 rdf:type schema:CreativeWork
    265 https://doi.org/10.1016/j.bbrc.2005.04.132 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051452418
    266 rdf:type schema:CreativeWork
    267 https://doi.org/10.1016/j.bbrc.2009.01.167 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019807620
    268 rdf:type schema:CreativeWork
    269 https://doi.org/10.1016/j.biomaterials.2006.10.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006778661
    270 rdf:type schema:CreativeWork
    271 https://doi.org/10.1016/j.bone.2005.04.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033181059
    272 rdf:type schema:CreativeWork
    273 https://doi.org/10.1016/j.bone.2006.06.010 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049214667
    274 rdf:type schema:CreativeWork
    275 https://doi.org/10.1016/j.bone.2006.09.008 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003255367
    276 rdf:type schema:CreativeWork
    277 https://doi.org/10.1016/j.bone.2007.03.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007854333
    278 rdf:type schema:CreativeWork
    279 https://doi.org/10.1016/j.bone.2008.03.024 schema:sameAs https://app.dimensions.ai/details/publication/pub.1042471171
    280 rdf:type schema:CreativeWork
    281 https://doi.org/10.1016/j.bone.2009.06.020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019835628
    282 rdf:type schema:CreativeWork
    283 https://doi.org/10.1016/j.bone.2010.05.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039864035
    284 rdf:type schema:CreativeWork
    285 https://doi.org/10.1016/j.cccn.2004.10.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035702716
    286 rdf:type schema:CreativeWork
    287 https://doi.org/10.1016/j.cellsig.2009.10.017 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004969019
    288 rdf:type schema:CreativeWork
    289 https://doi.org/10.1016/j.coph.2005.07.004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051647392
    290 rdf:type schema:CreativeWork
    291 https://doi.org/10.1016/j.healun.2004.03.020 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002600636
    292 rdf:type schema:CreativeWork
    293 https://doi.org/10.1016/j.jtbi.2004.03.023 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011358803
    294 rdf:type schema:CreativeWork
    295 https://doi.org/10.1016/j.mehy.2008.10.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028158802
    296 rdf:type schema:CreativeWork
    297 https://doi.org/10.1016/j.mehy.2009.10.047 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047787125
    298 rdf:type schema:CreativeWork
    299 https://doi.org/10.1016/j.tem.2004.01.006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011974546
    300 rdf:type schema:CreativeWork
    301 https://doi.org/10.1016/j.ygcen.2007.11.003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028228180
    302 rdf:type schema:CreativeWork
    303 https://doi.org/10.1016/s0002-9610(85)80050-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1029497463
    304 rdf:type schema:CreativeWork
    305 https://doi.org/10.1016/s0014-5793(97)00484-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019091548
    306 rdf:type schema:CreativeWork
    307 https://doi.org/10.1016/s0026-0495(97)90284-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045832587
    308 rdf:type schema:CreativeWork
    309 https://doi.org/10.1016/s0169-6009(08)80020-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039993895
    310 rdf:type schema:CreativeWork
    311 https://doi.org/10.1016/s0303-2647(03)00040-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007769720
    312 rdf:type schema:CreativeWork
    313 https://doi.org/10.1016/s0378-1119(01)00798-3 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024987111
    314 rdf:type schema:CreativeWork
    315 https://doi.org/10.1016/s0736-0266(01)00157-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032261231
    316 rdf:type schema:CreativeWork
    317 https://doi.org/10.1016/s0736-0266(03)00042-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022320544
    318 rdf:type schema:CreativeWork
    319 https://doi.org/10.1016/s0749-0690(02)00074-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045429078
    320 rdf:type schema:CreativeWork
    321 https://doi.org/10.1016/s1043-2760(01)00460-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1046293334
    322 rdf:type schema:CreativeWork
    323 https://doi.org/10.1016/s1043-2760(97)00060-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1040036140
    324 rdf:type schema:CreativeWork
    325 https://doi.org/10.1016/s8756-3282(03)00057-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1009160072
    326 rdf:type schema:CreativeWork
    327 https://doi.org/10.1016/s8756-3282(99)00263-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1031081075
    328 rdf:type schema:CreativeWork
    329 https://doi.org/10.1038/ki.1989.138 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015805771
    330 rdf:type schema:CreativeWork
    331 https://doi.org/10.1038/sj.bjp.0703830 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037462943
    332 rdf:type schema:CreativeWork
    333 https://doi.org/10.1046/j.0022-202x.2001.01410.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1036895262
    334 rdf:type schema:CreativeWork
    335 https://doi.org/10.1046/j.1525-1594.2003.07009.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1028735724
    336 rdf:type schema:CreativeWork
    337 https://doi.org/10.1073/pnas.95.12.7018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1050811163
    338 rdf:type schema:CreativeWork
    339 https://doi.org/10.1074/jbc.271.33.19888 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051336851
    340 rdf:type schema:CreativeWork
    341 https://doi.org/10.1074/jbc.273.6.3643 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005703051
    342 rdf:type schema:CreativeWork
    343 https://doi.org/10.1074/jbc.m003450200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021435743
    344 rdf:type schema:CreativeWork
    345 https://doi.org/10.1074/jbc.m007400200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039392495
    346 rdf:type schema:CreativeWork
    347 https://doi.org/10.1074/jbc.m705194200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001188492
    348 rdf:type schema:CreativeWork
    349 https://doi.org/10.1080/00016470410004012 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007041213
    350 rdf:type schema:CreativeWork
    351 https://doi.org/10.1080/15419060802310208 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013809339
    352 rdf:type schema:CreativeWork
    353 https://doi.org/10.1093/cvr/cvm080 schema:sameAs https://app.dimensions.ai/details/publication/pub.1046334750
    354 rdf:type schema:CreativeWork
    355 https://doi.org/10.1093/emboj/cdg172 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003588282
    356 rdf:type schema:CreativeWork
    357 https://doi.org/10.1093/oxfordjournals.jbchem.a002900 schema:sameAs https://app.dimensions.ai/details/publication/pub.1059959577
    358 rdf:type schema:CreativeWork
    359 https://doi.org/10.1097/01.mnh.0000133984.47806.00 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015574560
    360 rdf:type schema:CreativeWork
    361 https://doi.org/10.1097/med.0b013e32831a46d6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000183632
    362 rdf:type schema:CreativeWork
    363 https://doi.org/10.1111/j.1365-2362.2006.01664.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1036787136
    364 rdf:type schema:CreativeWork
    365 https://doi.org/10.1111/j.1440-1797.2009.01257.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1019608458
    366 rdf:type schema:CreativeWork
    367 https://doi.org/10.1111/j.1442-200x.1998.tb01407.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1039881951
    368 rdf:type schema:CreativeWork
    369 https://doi.org/10.1111/j.1749-6632.2009.05216.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1010560741
    370 rdf:type schema:CreativeWork
    371 https://doi.org/10.1128/jb.176.21.6489-6496.1994 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062723201
    372 rdf:type schema:CreativeWork
    373 https://doi.org/10.1152/ajpendo.00029.2005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044975767
    374 rdf:type schema:CreativeWork
    375 https://doi.org/10.1159/000191200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1002825391
    376 rdf:type schema:CreativeWork
    377 https://doi.org/10.1172/jci109327 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034822451
    378 rdf:type schema:CreativeWork
    379 https://doi.org/10.1172/jci11296 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016957718
    380 rdf:type schema:CreativeWork
    381 https://doi.org/10.1172/jci113885 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004728605
    382 rdf:type schema:CreativeWork
    383 https://doi.org/10.1172/jci11777 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023565430
    384 rdf:type schema:CreativeWork
    385 https://doi.org/10.1172/jci119491 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047036818
    386 rdf:type schema:CreativeWork
    387 https://doi.org/10.1172/jci14663 schema:sameAs https://app.dimensions.ai/details/publication/pub.1063415285
    388 rdf:type schema:CreativeWork
    389 https://doi.org/10.1177/1087057105279952 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034870735
    390 rdf:type schema:CreativeWork
    391 https://doi.org/10.1177/154405910308201006 schema:sameAs https://app.dimensions.ai/details/publication/pub.1034015686
    392 rdf:type schema:CreativeWork
    393 https://doi.org/10.1196/annals.1402.031 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053237154
    394 rdf:type schema:CreativeWork
    395 https://doi.org/10.1196/annals.1402.047 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001491831
    396 rdf:type schema:CreativeWork
    397 https://doi.org/10.1210/en.2002-220221 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064245769
    398 rdf:type schema:CreativeWork
    399 https://doi.org/10.1210/en.2002-220428 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043469931
    400 rdf:type schema:CreativeWork
    401 https://doi.org/10.1210/en.2002-221000 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064245923
    402 rdf:type schema:CreativeWork
    403 https://doi.org/10.1210/en.2004-1557 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064247240
    404 rdf:type schema:CreativeWork
    405 https://doi.org/10.1210/en.2004-1642 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064247272
    406 rdf:type schema:CreativeWork
    407 https://doi.org/10.1210/en.2005-0239 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064247371
    408 rdf:type schema:CreativeWork
    409 https://doi.org/10.1210/endo-110-2-506 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064256184
    410 rdf:type schema:CreativeWork
    411 https://doi.org/10.1210/endo-112-3-1000 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064257008
    412 rdf:type schema:CreativeWork
    413 https://doi.org/10.1210/jc.2003-030470 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064286867
    414 rdf:type schema:CreativeWork
    415 https://doi.org/10.1210/jc.2009-0233 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064291236
    416 rdf:type schema:CreativeWork
    417 https://doi.org/10.1210/jc.2010-1723 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064292374
    418 rdf:type schema:CreativeWork
    419 https://doi.org/10.1210/jc.81.10.3584 schema:sameAs https://app.dimensions.ai/details/publication/pub.1064298535
    420 rdf:type schema:CreativeWork
    421 https://doi.org/10.1359/jbmr.050602 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016126531
    422 rdf:type schema:CreativeWork
    423 https://doi.org/10.1359/jbmr.1999.14.1.11 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021583507
    424 rdf:type schema:CreativeWork
    425 https://doi.org/10.1359/jbmr.2000.15.1.175 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004799715
    426 rdf:type schema:CreativeWork
    427 https://doi.org/10.1359/jbmr.2000.15.3.550 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016601544
    428 rdf:type schema:CreativeWork
    429 https://doi.org/10.1359/jbmr.2000.15.4.740 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022913784
    430 rdf:type schema:CreativeWork
    431 https://doi.org/10.1359/jbmr.2000.15.7.1412 schema:sameAs https://app.dimensions.ai/details/publication/pub.1011457559
    432 rdf:type schema:CreativeWork
    433 https://doi.org/10.1359/jbmr.2003.18.7.1235 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038041744
    434 rdf:type schema:CreativeWork
    435 https://doi.org/10.1371/journal.pone.0012290 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015584669
    436 rdf:type schema:CreativeWork
    437 https://doi.org/10.1530/acta.0.1080217 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041097968
    438 rdf:type schema:CreativeWork
    439 https://doi.org/10.1615/critreveukaryotgeneexpr.v13.i1.30 schema:sameAs https://app.dimensions.ai/details/publication/pub.1068131427
    440 rdf:type schema:CreativeWork
    441 https://doi.org/10.1677/joe.1.06057 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021716230
    442 rdf:type schema:CreativeWork
    443 https://doi.org/10.1677/joe.1.06351 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038241444
    444 rdf:type schema:CreativeWork
    445 https://doi.org/10.2174/1381612013397780 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069164545
    446 rdf:type schema:CreativeWork
    447 https://doi.org/10.2174/1381612023393387 schema:sameAs https://app.dimensions.ai/details/publication/pub.1069164625
    448 rdf:type schema:CreativeWork
    449 https://doi.org/10.2174/1874192401004010110 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018501732
    450 rdf:type schema:CreativeWork
    451 https://doi.org/10.2215/cjn.01961205 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027649131
    452 rdf:type schema:CreativeWork
    453 https://doi.org/10.3109/03008200109016842 schema:sameAs https://app.dimensions.ai/details/publication/pub.1033572290
    454 rdf:type schema:CreativeWork
    455 https://doi.org/10.3171/foc.2001.11.2.8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071085245
    456 rdf:type schema:CreativeWork
    457 https://doi.org/10.5144/0256-4947.1999.110 schema:sameAs https://app.dimensions.ai/details/publication/pub.1077380154
    458 rdf:type schema:CreativeWork
    459 https://www.grid.ac/institutes/grid.194632.b schema:Organization
    460 https://www.grid.ac/institutes/grid.240416.5 schema:Organization
    461 https://www.grid.ac/institutes/grid.258331.e schema:Organization
     




    Preview window. Press ESC to close (or click here)


    ...