Cell-free system for synthesis of proteins derived from cultured mammalian cells


Ontology type: sgo:Patent     


Patent Info

DATE

2013-05-21T00:00

AUTHORS

Hiroaki Imataka , Satoshi Mikami , Shigeyuki Yokoyama

ABSTRACT

Prepared is an extract composition having an improved protein synthetic activity in a cell-free protein synthesis system using a mammalian cultured cell extract. An eukaryotic translation initiation factor and/or translational regulator are added to a cell-free protein synthesis system comprising an extract prepared from cultured mammalian cells and a template mRNA. These factors are one or more selected from the group consisting of eukaryotic translation initiation factors 4E (eIF4E), 2 (eIF2) and 2B (eIF2B), and eukaryotic translational regulator p97. More... »

Related SciGraph Publications

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/2581", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "name": "Hiroaki Imataka", 
        "type": "Person"
      }, 
      {
        "name": "Satoshi Mikami", 
        "type": "Person"
      }, 
      {
        "name": "Shigeyuki Yokoyama", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1128/jvi.79.11.6868-6881.2005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000032090"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00761774", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000395162", 
          "https://doi.org/10.1007/bf00761774"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00761774", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1000395162", 
          "https://doi.org/10.1007/bf00761774"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.271.36.22256", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001381379"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/prep.1997.0761", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003258691"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/prep.1997.0826", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1003755882"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aem.67.4.1885-1892.2001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004295469"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.082102499", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004734275"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1982.tb05867.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004875171"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.pep.2005.01.013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005364458"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.pep.2005.09.021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005704916"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.pep.2005.09.021", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005704916"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.100127597", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1006161022"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/abio.1993.1284", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007524023"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1261/rna.5164904", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007891757"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.273.25.15464", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010897059"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jvi.75.22.11205-11217.2001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012535256"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m206781200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012987636"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4781(84)90007-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015238382"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4781(84)90007-1", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015238382"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3136/nskkk.42.937", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015694485"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.87.5.1937", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016032578"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-2952(90)90190-v", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018188671"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0006-2952(90)90190-v", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018188671"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/26.19.4339", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019011544"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1385/abab:135:1:81", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019306041", 
          "https://doi.org/10.1385/abab:135:1:81"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.jmb.2007.05.087", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019669472"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.275.1.497", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020591770"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/bies.10362", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020997526"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1996.0881u.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021373231"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.79.11.3599", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022168512"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.89.11.4982", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022707838"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1073/pnas.77.12.7029", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022926934"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1023/b:jsfg.0000029204.57846.7d", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022949189", 
          "https://doi.org/10.1023/b:jsfg.0000029204.57846.7d"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0197-4580(87)90054-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023870270"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0197-4580(87)90054-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023870270"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jb.183.17.4958-4963.2001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1024396251"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj3320101", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025034082"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj3320101", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025034082"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2787(81)90223-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025064860"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0005-2787(81)90223-9", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025064860"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1970.tb01170.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025684871"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1515/bchm2.1979.360.2.1099", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1025695206"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj2950571", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026107773"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj2950571", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026107773"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1034/j.1600-0854.2001.020204.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026112975"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0042-6822(78)90118-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1027859815"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0014-5793(98)00715-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028329412"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/humupd/5.4.356", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1030385000"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj2860275", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031904012"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj2860275", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1031904012"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/emboj/20.19.5491", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032373203"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/nar/9.18.4459", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1032797599"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/emboj/17.24.7480", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035331881"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1002/(sici)1097-0290(19990720)64:2<194::aid-bit8>3.0.co;2-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035336333"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1263/jbb.106.8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035627372"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0300-9084(90)90030-k", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035957271"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0300-9084(90)90030-k", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1035957271"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4781(91)90011-a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037715016"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4781(91)90011-a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037715016"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00485547", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040166515", 
          "https://doi.org/10.1007/bf00485547"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00485547", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040166515", 
          "https://doi.org/10.1007/bf00485547"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m005642200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041354145"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0042-6822(80)90460-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041819908"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0014-5793(98)01620-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041832086"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/pl00000726", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043550913", 
          "https://doi.org/10.1007/pl00000726"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1976.tb10656.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044366922"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0168-1656(00)00326-6", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044853028"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.2004.04016.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045880125"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0922-338x(95)94212-a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047625788"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0922-338x(95)94212-a", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047625788"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00299141", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047938011", 
          "https://doi.org/10.1007/bf00299141"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf00299141", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1047938011", 
          "https://doi.org/10.1007/bf00299141"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1111/j.1432-1033.1988.tb13942.x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048038875"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0378-1119(89)90359-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048752288"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0378-1119(89)90359-4", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048752288"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0922-338x(95)94079-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048937447"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0922-338x(95)94079-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1048937447"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4781(85)90079-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049102430"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/0167-4781(85)90079-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049102430"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/emboj/16.4.817", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049227960"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1146/annurev.ge.07.120173.001411", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049958272"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj3170891", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051319936"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/bj3170891", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051319936"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1093/emboj/16.10.2703", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051964525"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1017/s1355838200001679", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1054923504"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi00471a022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055177505"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi025555g", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055195653"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi025555g", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055195653"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi960295m", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055211718"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/bi960295m", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055211718"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1099/mic.0.26490-0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060396801"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1925561", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062513734"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.3055301", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062586176"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/jb.174.12.3903-3914.1992", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062720576"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1128/aac.42.8.2041", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1083299310"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2013-05-21T00:00", 
    "description": "

Prepared is an extract composition having an improved protein synthetic activity in a cell-free protein synthesis system using a mammalian cultured cell extract. An eukaryotic translation initiation factor and/or translational regulator are added to a cell-free protein synthesis system comprising an extract prepared from cultured mammalian cells and a template mRNA. These factors are one or more selected from the group consisting of eukaryotic translation initiation factors 4E (eIF4E), 2 (eIF2) and 2B (eIF2B), and eukaryotic translational regulator p97.

", "id": "sg:patent.US-8445232-B2", "keywords": [ "cell-free system", "synthesis", "protein", "cultured mammalian cell", "composition", "synthetic activity", "protein synthesis", "cultured cell", "translation initiation factor", "translational regulator", "extract", "template", "Eukaryotic Initiation Factor-4E", "Eukaryotic Initiation Factor-2", "Eukaryotic Initiation Factor-2B" ], "name": "Cell-free system for synthesis of proteins derived from cultured mammalian cells", "recipient": [ { "id": "https://www.grid.ac/institutes/grid.7597.c", "type": "Organization" } ], "sameAs": [ "https://app.dimensions.ai/details/patent/US-8445232-B2" ], "sdDataset": "patents", "sdDatePublished": "2019-04-18T10:11", "sdLicense": "https://scigraph.springernature.com/explorer/license/", "sdPublisher": { "name": "Springer Nature - SN SciGraph project", "type": "Organization" }, "sdSource": "s3://com-uberresearch-data-patents-target-20190320-rc/data/sn-export/402f166718b70575fb5d4ffe01f064d1/0000100128-0000352499/json_export_00519.jsonl", "type": "Patent" } ]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/patent.US-8445232-B2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/patent.US-8445232-B2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/patent.US-8445232-B2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/patent.US-8445232-B2'


 

This table displays all metadata directly associated to this object as RDF triples.

279 TRIPLES      15 PREDICATES      105 URIs      23 LITERALS      2 BLANK NODES

Subject Predicate Object
1 sg:patent.US-8445232-B2 schema:about anzsrc-for:2581
2 schema:author N3aea8adb168d4184ac9503cda23d6151
3 schema:citation sg:pub.10.1007/bf00299141
4 sg:pub.10.1007/bf00485547
5 sg:pub.10.1007/bf00761774
6 sg:pub.10.1007/pl00000726
7 sg:pub.10.1023/b:jsfg.0000029204.57846.7d
8 sg:pub.10.1385/abab:135:1:81
9 https://doi.org/10.1002/(sici)1097-0290(19990720)64:2<194::aid-bit8>3.0.co;2-5
10 https://doi.org/10.1002/bies.10362
11 https://doi.org/10.1006/abio.1993.1284
12 https://doi.org/10.1006/prep.1997.0761
13 https://doi.org/10.1006/prep.1997.0826
14 https://doi.org/10.1016/0005-2787(81)90223-9
15 https://doi.org/10.1016/0006-2952(90)90190-v
16 https://doi.org/10.1016/0042-6822(78)90118-6
17 https://doi.org/10.1016/0042-6822(80)90460-2
18 https://doi.org/10.1016/0167-4781(84)90007-1
19 https://doi.org/10.1016/0167-4781(85)90079-x
20 https://doi.org/10.1016/0167-4781(91)90011-a
21 https://doi.org/10.1016/0197-4580(87)90054-6
22 https://doi.org/10.1016/0300-9084(90)90030-k
23 https://doi.org/10.1016/0378-1119(89)90359-4
24 https://doi.org/10.1016/0922-338x(95)94079-7
25 https://doi.org/10.1016/0922-338x(95)94212-a
26 https://doi.org/10.1016/j.jmb.2007.05.087
27 https://doi.org/10.1016/j.pep.2005.01.013
28 https://doi.org/10.1016/j.pep.2005.09.021
29 https://doi.org/10.1016/s0014-5793(98)00715-7
30 https://doi.org/10.1016/s0014-5793(98)01620-2
31 https://doi.org/10.1016/s0168-1656(00)00326-6
32 https://doi.org/10.1017/s1355838200001679
33 https://doi.org/10.1021/bi00471a022
34 https://doi.org/10.1021/bi025555g
35 https://doi.org/10.1021/bi960295m
36 https://doi.org/10.1034/j.1600-0854.2001.020204.x
37 https://doi.org/10.1042/bj2860275
38 https://doi.org/10.1042/bj2950571
39 https://doi.org/10.1042/bj3170891
40 https://doi.org/10.1042/bj3320101
41 https://doi.org/10.1073/pnas.082102499
42 https://doi.org/10.1073/pnas.100127597
43 https://doi.org/10.1073/pnas.77.12.7029
44 https://doi.org/10.1073/pnas.79.11.3599
45 https://doi.org/10.1073/pnas.87.5.1937
46 https://doi.org/10.1073/pnas.89.11.4982
47 https://doi.org/10.1074/jbc.271.36.22256
48 https://doi.org/10.1074/jbc.273.25.15464
49 https://doi.org/10.1074/jbc.275.1.497
50 https://doi.org/10.1074/jbc.m005642200
51 https://doi.org/10.1074/jbc.m206781200
52 https://doi.org/10.1093/emboj/16.10.2703
53 https://doi.org/10.1093/emboj/16.4.817
54 https://doi.org/10.1093/emboj/17.24.7480
55 https://doi.org/10.1093/emboj/20.19.5491
56 https://doi.org/10.1093/humupd/5.4.356
57 https://doi.org/10.1093/nar/26.19.4339
58 https://doi.org/10.1093/nar/9.18.4459
59 https://doi.org/10.1099/mic.0.26490-0
60 https://doi.org/10.1111/j.1432-1033.1970.tb01170.x
61 https://doi.org/10.1111/j.1432-1033.1976.tb10656.x
62 https://doi.org/10.1111/j.1432-1033.1982.tb05867.x
63 https://doi.org/10.1111/j.1432-1033.1988.tb13942.x
64 https://doi.org/10.1111/j.1432-1033.1996.0881u.x
65 https://doi.org/10.1111/j.1432-1033.2004.04016.x
66 https://doi.org/10.1126/science.1925561
67 https://doi.org/10.1126/science.3055301
68 https://doi.org/10.1128/aac.42.8.2041
69 https://doi.org/10.1128/aem.67.4.1885-1892.2001
70 https://doi.org/10.1128/jb.174.12.3903-3914.1992
71 https://doi.org/10.1128/jb.183.17.4958-4963.2001
72 https://doi.org/10.1128/jvi.75.22.11205-11217.2001
73 https://doi.org/10.1128/jvi.79.11.6868-6881.2005
74 https://doi.org/10.1146/annurev.ge.07.120173.001411
75 https://doi.org/10.1261/rna.5164904
76 https://doi.org/10.1263/jbb.106.8
77 https://doi.org/10.1515/bchm2.1979.360.2.1099
78 https://doi.org/10.3136/nskkk.42.937
79 schema:datePublished 2013-05-21T00:00
80 schema:description <p num="p-0001">Prepared is an extract composition having an improved protein synthetic activity in a cell-free protein synthesis system using a mammalian cultured cell extract. An eukaryotic translation initiation factor and/or translational regulator are added to a cell-free protein synthesis system comprising an extract prepared from cultured mammalian cells and a template mRNA. These factors are one or more selected from the group consisting of eukaryotic translation initiation factors 4E (eIF4E), 2 (eIF2) and 2B (eIF2B), and eukaryotic translational regulator p97.</p>
81 schema:keywords Eukaryotic Initiation Factor-2
82 Eukaryotic Initiation Factor-2B
83 Eukaryotic Initiation Factor-4E
84 cell-free system
85 composition
86 cultured cell
87 cultured mammalian cell
88 extract
89 protein
90 protein synthesis
91 synthesis
92 synthetic activity
93 template
94 translation initiation factor
95 translational regulator
96 schema:name Cell-free system for synthesis of proteins derived from cultured mammalian cells
97 schema:recipient https://www.grid.ac/institutes/grid.7597.c
98 schema:sameAs https://app.dimensions.ai/details/patent/US-8445232-B2
99 schema:sdDatePublished 2019-04-18T10:11
100 schema:sdLicense https://scigraph.springernature.com/explorer/license/
101 schema:sdPublisher Nba9ea3a9c40a48c684692b5479062ce0
102 sgo:license sg:explorer/license/
103 sgo:sdDataset patents
104 rdf:type sgo:Patent
105 N3aea8adb168d4184ac9503cda23d6151 rdf:first N9611bf559d7b4e7d8e031ecc9b1b1a72
106 rdf:rest N78afecc1a4a245159c06cf692f967565
107 N487e21046aec453f815ab4aea35b9134 schema:name Satoshi Mikami
108 rdf:type schema:Person
109 N5eb5e5e59aa44f9da7316177bcc4082b schema:name Shigeyuki Yokoyama
110 rdf:type schema:Person
111 N6c50cc56036a40db99571782a9a736ed rdf:first N5eb5e5e59aa44f9da7316177bcc4082b
112 rdf:rest rdf:nil
113 N78afecc1a4a245159c06cf692f967565 rdf:first N487e21046aec453f815ab4aea35b9134
114 rdf:rest N6c50cc56036a40db99571782a9a736ed
115 N9611bf559d7b4e7d8e031ecc9b1b1a72 schema:name Hiroaki Imataka
116 rdf:type schema:Person
117 Nba9ea3a9c40a48c684692b5479062ce0 schema:name Springer Nature - SN SciGraph project
118 rdf:type schema:Organization
119 anzsrc-for:2581 schema:inDefinedTermSet anzsrc-for:
120 rdf:type schema:DefinedTerm
121 sg:pub.10.1007/bf00299141 schema:sameAs https://app.dimensions.ai/details/publication/pub.1047938011
122 https://doi.org/10.1007/bf00299141
123 rdf:type schema:CreativeWork
124 sg:pub.10.1007/bf00485547 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040166515
125 https://doi.org/10.1007/bf00485547
126 rdf:type schema:CreativeWork
127 sg:pub.10.1007/bf00761774 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000395162
128 https://doi.org/10.1007/bf00761774
129 rdf:type schema:CreativeWork
130 sg:pub.10.1007/pl00000726 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043550913
131 https://doi.org/10.1007/pl00000726
132 rdf:type schema:CreativeWork
133 sg:pub.10.1023/b:jsfg.0000029204.57846.7d schema:sameAs https://app.dimensions.ai/details/publication/pub.1022949189
134 https://doi.org/10.1023/b:jsfg.0000029204.57846.7d
135 rdf:type schema:CreativeWork
136 sg:pub.10.1385/abab:135:1:81 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019306041
137 https://doi.org/10.1385/abab:135:1:81
138 rdf:type schema:CreativeWork
139 https://doi.org/10.1002/(sici)1097-0290(19990720)64:2<194::aid-bit8>3.0.co;2-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035336333
140 rdf:type schema:CreativeWork
141 https://doi.org/10.1002/bies.10362 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020997526
142 rdf:type schema:CreativeWork
143 https://doi.org/10.1006/abio.1993.1284 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007524023
144 rdf:type schema:CreativeWork
145 https://doi.org/10.1006/prep.1997.0761 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003258691
146 rdf:type schema:CreativeWork
147 https://doi.org/10.1006/prep.1997.0826 schema:sameAs https://app.dimensions.ai/details/publication/pub.1003755882
148 rdf:type schema:CreativeWork
149 https://doi.org/10.1016/0005-2787(81)90223-9 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025064860
150 rdf:type schema:CreativeWork
151 https://doi.org/10.1016/0006-2952(90)90190-v schema:sameAs https://app.dimensions.ai/details/publication/pub.1018188671
152 rdf:type schema:CreativeWork
153 https://doi.org/10.1016/0042-6822(78)90118-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1027859815
154 rdf:type schema:CreativeWork
155 https://doi.org/10.1016/0042-6822(80)90460-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041819908
156 rdf:type schema:CreativeWork
157 https://doi.org/10.1016/0167-4781(84)90007-1 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015238382
158 rdf:type schema:CreativeWork
159 https://doi.org/10.1016/0167-4781(85)90079-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1049102430
160 rdf:type schema:CreativeWork
161 https://doi.org/10.1016/0167-4781(91)90011-a schema:sameAs https://app.dimensions.ai/details/publication/pub.1037715016
162 rdf:type schema:CreativeWork
163 https://doi.org/10.1016/0197-4580(87)90054-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023870270
164 rdf:type schema:CreativeWork
165 https://doi.org/10.1016/0300-9084(90)90030-k schema:sameAs https://app.dimensions.ai/details/publication/pub.1035957271
166 rdf:type schema:CreativeWork
167 https://doi.org/10.1016/0378-1119(89)90359-4 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048752288
168 rdf:type schema:CreativeWork
169 https://doi.org/10.1016/0922-338x(95)94079-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1048937447
170 rdf:type schema:CreativeWork
171 https://doi.org/10.1016/0922-338x(95)94212-a schema:sameAs https://app.dimensions.ai/details/publication/pub.1047625788
172 rdf:type schema:CreativeWork
173 https://doi.org/10.1016/j.jmb.2007.05.087 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019669472
174 rdf:type schema:CreativeWork
175 https://doi.org/10.1016/j.pep.2005.01.013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005364458
176 rdf:type schema:CreativeWork
177 https://doi.org/10.1016/j.pep.2005.09.021 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005704916
178 rdf:type schema:CreativeWork
179 https://doi.org/10.1016/s0014-5793(98)00715-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028329412
180 rdf:type schema:CreativeWork
181 https://doi.org/10.1016/s0014-5793(98)01620-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041832086
182 rdf:type schema:CreativeWork
183 https://doi.org/10.1016/s0168-1656(00)00326-6 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044853028
184 rdf:type schema:CreativeWork
185 https://doi.org/10.1017/s1355838200001679 schema:sameAs https://app.dimensions.ai/details/publication/pub.1054923504
186 rdf:type schema:CreativeWork
187 https://doi.org/10.1021/bi00471a022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055177505
188 rdf:type schema:CreativeWork
189 https://doi.org/10.1021/bi025555g schema:sameAs https://app.dimensions.ai/details/publication/pub.1055195653
190 rdf:type schema:CreativeWork
191 https://doi.org/10.1021/bi960295m schema:sameAs https://app.dimensions.ai/details/publication/pub.1055211718
192 rdf:type schema:CreativeWork
193 https://doi.org/10.1034/j.1600-0854.2001.020204.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1026112975
194 rdf:type schema:CreativeWork
195 https://doi.org/10.1042/bj2860275 schema:sameAs https://app.dimensions.ai/details/publication/pub.1031904012
196 rdf:type schema:CreativeWork
197 https://doi.org/10.1042/bj2950571 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026107773
198 rdf:type schema:CreativeWork
199 https://doi.org/10.1042/bj3170891 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051319936
200 rdf:type schema:CreativeWork
201 https://doi.org/10.1042/bj3320101 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025034082
202 rdf:type schema:CreativeWork
203 https://doi.org/10.1073/pnas.082102499 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004734275
204 rdf:type schema:CreativeWork
205 https://doi.org/10.1073/pnas.100127597 schema:sameAs https://app.dimensions.ai/details/publication/pub.1006161022
206 rdf:type schema:CreativeWork
207 https://doi.org/10.1073/pnas.77.12.7029 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022926934
208 rdf:type schema:CreativeWork
209 https://doi.org/10.1073/pnas.79.11.3599 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022168512
210 rdf:type schema:CreativeWork
211 https://doi.org/10.1073/pnas.87.5.1937 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016032578
212 rdf:type schema:CreativeWork
213 https://doi.org/10.1073/pnas.89.11.4982 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022707838
214 rdf:type schema:CreativeWork
215 https://doi.org/10.1074/jbc.271.36.22256 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001381379
216 rdf:type schema:CreativeWork
217 https://doi.org/10.1074/jbc.273.25.15464 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010897059
218 rdf:type schema:CreativeWork
219 https://doi.org/10.1074/jbc.275.1.497 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020591770
220 rdf:type schema:CreativeWork
221 https://doi.org/10.1074/jbc.m005642200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041354145
222 rdf:type schema:CreativeWork
223 https://doi.org/10.1074/jbc.m206781200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012987636
224 rdf:type schema:CreativeWork
225 https://doi.org/10.1093/emboj/16.10.2703 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051964525
226 rdf:type schema:CreativeWork
227 https://doi.org/10.1093/emboj/16.4.817 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049227960
228 rdf:type schema:CreativeWork
229 https://doi.org/10.1093/emboj/17.24.7480 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035331881
230 rdf:type schema:CreativeWork
231 https://doi.org/10.1093/emboj/20.19.5491 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032373203
232 rdf:type schema:CreativeWork
233 https://doi.org/10.1093/humupd/5.4.356 schema:sameAs https://app.dimensions.ai/details/publication/pub.1030385000
234 rdf:type schema:CreativeWork
235 https://doi.org/10.1093/nar/26.19.4339 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019011544
236 rdf:type schema:CreativeWork
237 https://doi.org/10.1093/nar/9.18.4459 schema:sameAs https://app.dimensions.ai/details/publication/pub.1032797599
238 rdf:type schema:CreativeWork
239 https://doi.org/10.1099/mic.0.26490-0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060396801
240 rdf:type schema:CreativeWork
241 https://doi.org/10.1111/j.1432-1033.1970.tb01170.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1025684871
242 rdf:type schema:CreativeWork
243 https://doi.org/10.1111/j.1432-1033.1976.tb10656.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1044366922
244 rdf:type schema:CreativeWork
245 https://doi.org/10.1111/j.1432-1033.1982.tb05867.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1004875171
246 rdf:type schema:CreativeWork
247 https://doi.org/10.1111/j.1432-1033.1988.tb13942.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1048038875
248 rdf:type schema:CreativeWork
249 https://doi.org/10.1111/j.1432-1033.1996.0881u.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1021373231
250 rdf:type schema:CreativeWork
251 https://doi.org/10.1111/j.1432-1033.2004.04016.x schema:sameAs https://app.dimensions.ai/details/publication/pub.1045880125
252 rdf:type schema:CreativeWork
253 https://doi.org/10.1126/science.1925561 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062513734
254 rdf:type schema:CreativeWork
255 https://doi.org/10.1126/science.3055301 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062586176
256 rdf:type schema:CreativeWork
257 https://doi.org/10.1128/aac.42.8.2041 schema:sameAs https://app.dimensions.ai/details/publication/pub.1083299310
258 rdf:type schema:CreativeWork
259 https://doi.org/10.1128/aem.67.4.1885-1892.2001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004295469
260 rdf:type schema:CreativeWork
261 https://doi.org/10.1128/jb.174.12.3903-3914.1992 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062720576
262 rdf:type schema:CreativeWork
263 https://doi.org/10.1128/jb.183.17.4958-4963.2001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1024396251
264 rdf:type schema:CreativeWork
265 https://doi.org/10.1128/jvi.75.22.11205-11217.2001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012535256
266 rdf:type schema:CreativeWork
267 https://doi.org/10.1128/jvi.79.11.6868-6881.2005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1000032090
268 rdf:type schema:CreativeWork
269 https://doi.org/10.1146/annurev.ge.07.120173.001411 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049958272
270 rdf:type schema:CreativeWork
271 https://doi.org/10.1261/rna.5164904 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007891757
272 rdf:type schema:CreativeWork
273 https://doi.org/10.1263/jbb.106.8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1035627372
274 rdf:type schema:CreativeWork
275 https://doi.org/10.1515/bchm2.1979.360.2.1099 schema:sameAs https://app.dimensions.ai/details/publication/pub.1025695206
276 rdf:type schema:CreativeWork
277 https://doi.org/10.3136/nskkk.42.937 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015694485
278 rdf:type schema:CreativeWork
279 https://www.grid.ac/institutes/grid.7597.c schema:Organization
 




Preview window. Press ESC to close (or click here)


...