Method for producing insulin analogs having a dibasic B chain terminus


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

Paul Habermann , Frank Zocher

ABSTRACT

The invention relates to a method for producing a type of insulin by genetically engineering a precursor thereof and converting said precursor to the respective insulin in an enzyme-catalyzed ligation reaction with lysine amide or arginine amide, or by lysine or arginine which is modified by protective groups, and optionally subsequent hydrolysis. More... »

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