Aminopyrimidines useful as kinase inhibitors


Ontology type: sgo:Patent     


Patent Info

DATE

2013-02-26T00:00

AUTHORS

MORTIMORE MICHAEL , GOLEC JULIAN , ROBINSON DANIEL , STUDLEY JOHN

ABSTRACT

The present invention relates to compounds useful as inhibitors of Aurora protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention. More... »

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/34", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }, 
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/3404", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "name": "MORTIMORE MICHAEL", 
        "type": "Person"
      }, 
      {
        "name": "GOLEC JULIAN", 
        "type": "Person"
      }, 
      {
        "name": "ROBINSON DANIEL", 
        "type": "Person"
      }, 
      {
        "name": "STUDLEY JOHN", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "sg:pub.10.1038/357161a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022093620", 
          "https://doi.org/10.1038/357161a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.2165/00002512-199507060-00007", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052340990", 
          "https://doi.org/10.2165/00002512-199507060-00007"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35048096", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051541099", 
          "https://doi.org/10.1038/35048096"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1007/bf02252107", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020940579", 
          "https://doi.org/10.1007/bf02252107"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/35096075", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049241198", 
          "https://doi.org/10.1038/35096075"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm1003", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014550555", 
          "https://doi.org/10.1038/nm1003"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1054/bjoc.2001.1796", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026993418", 
          "https://doi.org/10.1054/bjoc.2001.1796"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/343651a0", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1015375932", 
          "https://doi.org/10.1038/343651a0"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/27208", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1053209158", 
          "https://doi.org/10.1038/27208"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1385/jmn:19:3:275", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016328080", 
          "https://doi.org/10.1385/jmn:19:3:275"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/sj.onc.1203598", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051386685", 
          "https://doi.org/10.1038/sj.onc.1203598"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "datePublished": "2013-02-26T00:00", 
    "description": "

The present invention relates to compounds useful as inhibitors of Aurora protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.

", "endDate": "2029-06-19", "id": "sg:patent.US-8383633-B2", "name": "Aminopyrimidines useful as kinase inhibitors", "recipient": [ { "id": "http://www.grid.ac/institutes/grid.422219.e", "type": "Organization" } ], "sameAs": [ "https://app.dimensions.ai/details/patent/US-8383633-B2" ], "sdDataset": "patents", "sdDatePublished": "2022-12-01T06:59", "sdLicense": "https://scigraph.springernature.com/explorer/license/", "sdPublisher": { "name": "Springer Nature - SN SciGraph project", "type": "Organization" }, "sdSource": "s3://com-springernature-scigraph/baseset/20221201/entities/gbq_results/patent/patent_40.jsonl", "type": "Patent" } ]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/patent.US-8383633-B2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/patent.US-8383633-B2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/patent.US-8383633-B2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/patent.US-8383633-B2'


 

This table displays all metadata directly associated to this object as RDF triples.

82 TRIPLES      15 PREDICATES      27 URIs      9 LITERALS      2 BLANK NODES

Subject Predicate Object
1 sg:patent.US-8383633-B2 schema:about anzsrc-for:34
2 anzsrc-for:3404
3 schema:author N060ae5f858e64cc2b4e4cce377dd444f
4 schema:citation sg:pub.10.1007/bf02252107
5 sg:pub.10.1038/27208
6 sg:pub.10.1038/343651a0
7 sg:pub.10.1038/35048096
8 sg:pub.10.1038/35096075
9 sg:pub.10.1038/357161a0
10 sg:pub.10.1038/nm1003
11 sg:pub.10.1038/sj.onc.1203598
12 sg:pub.10.1054/bjoc.2001.1796
13 sg:pub.10.1385/jmn:19:3:275
14 sg:pub.10.2165/00002512-199507060-00007
15 schema:datePublished 2013-02-26T00:00
16 schema:description <p num="p-0001">The present invention relates to compounds useful as inhibitors of Aurora protein kinases. The invention also provides pharmaceutically acceptable compositions comprising those compounds and methods of using the compounds and compositions in the treatment of various disease, conditions, and disorders. The invention also provides processes for preparing compounds of the invention.</p>
17 schema:endDate 2029-06-19
18 schema:name Aminopyrimidines useful as kinase inhibitors
19 schema:recipient grid-institutes:grid.422219.e
20 schema:sameAs https://app.dimensions.ai/details/patent/US-8383633-B2
21 schema:sdDatePublished 2022-12-01T06:59
22 schema:sdLicense https://scigraph.springernature.com/explorer/license/
23 schema:sdPublisher Na16b0bf8a3994f2aa36fcf57d72f293e
24 sgo:license sg:explorer/license/
25 sgo:sdDataset patents
26 rdf:type sgo:Patent
27 N03945144c39f479ba74bf39212d35221 rdf:first Neeec484c90fc4df9ae84af451649f6be
28 rdf:rest rdf:nil
29 N060ae5f858e64cc2b4e4cce377dd444f rdf:first N9bb588680392494a86cdbb45df8d17f9
30 rdf:rest N08ec60a753d44acf8a67b6d60ad6b459
31 N08ec60a753d44acf8a67b6d60ad6b459 rdf:first N69ff13ee6cef4cefba98b08125d55e1f
32 rdf:rest Nd67a0ea4ffb44341ac464603d1ceed20
33 N69ff13ee6cef4cefba98b08125d55e1f schema:name GOLEC JULIAN
34 rdf:type schema:Person
35 N9bb588680392494a86cdbb45df8d17f9 schema:name MORTIMORE MICHAEL
36 rdf:type schema:Person
37 Na16b0bf8a3994f2aa36fcf57d72f293e schema:name Springer Nature - SN SciGraph project
38 rdf:type schema:Organization
39 Nc711eaab9ee04ceeaddca2e9fe8dffc9 schema:name ROBINSON DANIEL
40 rdf:type schema:Person
41 Nd67a0ea4ffb44341ac464603d1ceed20 rdf:first Nc711eaab9ee04ceeaddca2e9fe8dffc9
42 rdf:rest N03945144c39f479ba74bf39212d35221
43 Neeec484c90fc4df9ae84af451649f6be schema:name STUDLEY JOHN
44 rdf:type schema:Person
45 anzsrc-for:34 schema:inDefinedTermSet anzsrc-for:
46 rdf:type schema:DefinedTerm
47 anzsrc-for:3404 schema:inDefinedTermSet anzsrc-for:
48 rdf:type schema:DefinedTerm
49 sg:pub.10.1007/bf02252107 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020940579
50 https://doi.org/10.1007/bf02252107
51 rdf:type schema:CreativeWork
52 sg:pub.10.1038/27208 schema:sameAs https://app.dimensions.ai/details/publication/pub.1053209158
53 https://doi.org/10.1038/27208
54 rdf:type schema:CreativeWork
55 sg:pub.10.1038/343651a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1015375932
56 https://doi.org/10.1038/343651a0
57 rdf:type schema:CreativeWork
58 sg:pub.10.1038/35048096 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051541099
59 https://doi.org/10.1038/35048096
60 rdf:type schema:CreativeWork
61 sg:pub.10.1038/35096075 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049241198
62 https://doi.org/10.1038/35096075
63 rdf:type schema:CreativeWork
64 sg:pub.10.1038/357161a0 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022093620
65 https://doi.org/10.1038/357161a0
66 rdf:type schema:CreativeWork
67 sg:pub.10.1038/nm1003 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014550555
68 https://doi.org/10.1038/nm1003
69 rdf:type schema:CreativeWork
70 sg:pub.10.1038/sj.onc.1203598 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051386685
71 https://doi.org/10.1038/sj.onc.1203598
72 rdf:type schema:CreativeWork
73 sg:pub.10.1054/bjoc.2001.1796 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026993418
74 https://doi.org/10.1054/bjoc.2001.1796
75 rdf:type schema:CreativeWork
76 sg:pub.10.1385/jmn:19:3:275 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016328080
77 https://doi.org/10.1385/jmn:19:3:275
78 rdf:type schema:CreativeWork
79 sg:pub.10.2165/00002512-199507060-00007 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052340990
80 https://doi.org/10.2165/00002512-199507060-00007
81 rdf:type schema:CreativeWork
82 grid-institutes:grid.422219.e schema:Organization
 




Preview window. Press ESC to close (or click here)


...