Substituted isoquinoline and isoquinolinone derivatives as inhibitors of Rho-kinase


Ontology type: sgo:Patent     


Patent Info

DATE

N/A

AUTHORS

Oliver Plettenburg , Armin Hofmeister , Joachim Brendel , Matthias Lohn

ABSTRACT

The invention relates to 6-substituted isoquinoline and isochinolone derivatives of the formula (I) useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.

JSON-LD is the canonical representation for SciGraph data.

TIP: You can open this SciGraph record using an external JSON-LD service: JSON-LD Playground Google SDTT

[
  {
    "@context": "https://springernature.github.io/scigraph/jsonld/sgcontext.json", 
    "about": [
      {
        "id": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/2464", 
        "inDefinedTermSet": "http://purl.org/au-research/vocabulary/anzsrc-for/2008/", 
        "type": "DefinedTerm"
      }
    ], 
    "author": [
      {
        "name": "Oliver Plettenburg", 
        "type": "Person"
      }, 
      {
        "name": "Armin Hofmeister", 
        "type": "Person"
      }, 
      {
        "name": "Joachim Brendel", 
        "type": "Person"
      }, 
      {
        "name": "Matthias Lohn", 
        "type": "Person"
      }
    ], 
    "citation": [
      {
        "id": "https://doi.org/10.1006/bbrc.1999.1129", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1001678672"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.tetlet.2003.09.111", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1004451980"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0024-3205(00)00781-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005152800"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1136/hrt.2003.029470", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1005770183"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1165/ajrcmb.20.6.3441", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007741147"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.res.87.3.195", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1007984386"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/nm1060", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1008244498", 
          "https://doi.org/10.1038/nm1060"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/circulationaha.104.510248", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1010793417"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.cir.0000127939.16111.58", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012182298"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.res.84.10.1186", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1012623433"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1177/1087057104264175", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1013582821"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0014-2999(00)00593-8", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014226389"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/40187", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1014459412", 
          "https://doi.org/10.1038/40187"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0968-0896(99)00203-5", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1016280749"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005344-200211000-00013", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1018127331"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejphar.2005.03.001", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1019606213"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0957-4166(97)00191-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1020735778"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0898-6568(00)00108-x", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021232407"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.ejphar.2005.10.018", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021280840"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/bbrc.2000.2315", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021388923"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.res.0000078780.65824.8b", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1021821469"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1083/jcb.144.4.745", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1022866344"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.275.5304.1308", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1023493290"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.273.10.5542", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1026994523"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1152/japplphysiol.01104.2004", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028089859"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bmc.2004.02.025", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1028659501"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/op010223p", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1029472773"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jo071202h", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1034962313"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "sg:pub.10.1038/83258", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036056981", 
          "https://doi.org/10.1038/83258"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0014-5793(99)01762-7", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1036369220"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.neuroscience.2004.10.022", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1037010762"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1083/jcb.150.4.797", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038018222"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1038/sj.bjp.0703780", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1038114477"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bmc.2006.09.052", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039348608"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0021-9150(00)00585-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1039629074"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bmc.2006.10.028", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1040282186"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/hc1002.105938", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1041921770"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1074/jbc.m211074200", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043307681"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0024-3205(01)01229-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1043670828"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1006/bbrc.2000.2343", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044162166"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.bbapap.2005.06.015", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1044932832"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/j.cmet.2005.06.011", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1045928669"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1016/s0014-2999(99)00891-2", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049451145"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1161/01.hyp.35.1.313", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1049690454"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.2337/diabetes.49.12.2178", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1051306915"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1248/cpb.42.57", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1052992913"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1021/jm00178a014", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1055937922"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1042/0264-6021:3480273", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1056714768"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1055/s-1992-26307", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1057394717"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00005344-200002000-00005", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060206946"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1097/00006123-200002000-00033", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1060250588"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1126/science.1090154", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1062448978"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.1358/dnp.2005.18.10.959578", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1065057677"
        ], 
        "type": "CreativeWork"
      }, 
      {
        "id": "https://doi.org/10.3171/spi.2000.93.1.0094", 
        "sameAs": [
          "https://app.dimensions.ai/details/publication/pub.1071103218"
        ], 
        "type": "CreativeWork"
      }
    ], 
    "description": "

The invention relates to 6-substituted isoquinoline and isochinolone derivatives of the formula (I)

\"embedded
\nuseful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.\n

", "id": "sg:patent.US-8278294-B2", "keywords": [ "derivative", "inhibitor", "rho-Associated Kinase", "invention", "formula", "prevention", "disease", "Rho", "mediated phosphorylation", "Myosin-Light-Chain Phosphatase", "composition", "compound" ], "name": "Substituted isoquinoline and isoquinolinone derivatives as inhibitors of Rho-kinase", "recipient": [ { "id": "https://www.grid.ac/institutes/grid.417924.d", "type": "Organization" } ], "sameAs": [ "https://app.dimensions.ai/details/patent/US-8278294-B2" ], "sdDataset": "patents", "sdDatePublished": "2019-03-07T15:35", "sdLicense": "https://scigraph.springernature.com/explorer/license/", "sdPublisher": { "name": "Springer Nature - SN SciGraph project", "type": "Organization" }, "sdSource": "s3://com.uberresearch.data.dev.patents-pipeline/full_run_10/sn-export/5eb3e5a348d7f117b22cc85fb0b02730/0000100128-0000348334/json_export_b670b59c.jsonl", "type": "Patent" } ]
 

Download the RDF metadata as:  json-ld nt turtle xml License info

HOW TO GET THIS DATA PROGRAMMATICALLY:

JSON-LD is a popular format for linked data which is fully compatible with JSON.

curl -H 'Accept: application/ld+json' 'https://scigraph.springernature.com/patent.US-8278294-B2'

N-Triples is a line-based linked data format ideal for batch operations.

curl -H 'Accept: application/n-triples' 'https://scigraph.springernature.com/patent.US-8278294-B2'

Turtle is a human-readable linked data format.

curl -H 'Accept: text/turtle' 'https://scigraph.springernature.com/patent.US-8278294-B2'

RDF/XML is a standard XML format for linked data.

curl -H 'Accept: application/rdf+xml' 'https://scigraph.springernature.com/patent.US-8278294-B2'


 

This table displays all metadata directly associated to this object as RDF triples.

210 TRIPLES      14 PREDICATES      79 URIs      19 LITERALS      2 BLANK NODES

Subject Predicate Object
1 sg:patent.US-8278294-B2 schema:about anzsrc-for:2464
2 schema:author Nf6aaa62978f5410abfc091364f0e1596
3 schema:citation sg:pub.10.1038/40187
4 sg:pub.10.1038/83258
5 sg:pub.10.1038/nm1060
6 https://doi.org/10.1006/bbrc.1999.1129
7 https://doi.org/10.1006/bbrc.2000.2315
8 https://doi.org/10.1006/bbrc.2000.2343
9 https://doi.org/10.1016/j.bbapap.2005.06.015
10 https://doi.org/10.1016/j.bmc.2004.02.025
11 https://doi.org/10.1016/j.bmc.2006.09.052
12 https://doi.org/10.1016/j.bmc.2006.10.028
13 https://doi.org/10.1016/j.cmet.2005.06.011
14 https://doi.org/10.1016/j.ejphar.2005.03.001
15 https://doi.org/10.1016/j.ejphar.2005.10.018
16 https://doi.org/10.1016/j.neuroscience.2004.10.022
17 https://doi.org/10.1016/j.tetlet.2003.09.111
18 https://doi.org/10.1016/s0014-2999(00)00593-8
19 https://doi.org/10.1016/s0014-2999(99)00891-2
20 https://doi.org/10.1016/s0014-5793(99)01762-7
21 https://doi.org/10.1016/s0021-9150(00)00585-2
22 https://doi.org/10.1016/s0024-3205(00)00781-5
23 https://doi.org/10.1016/s0024-3205(01)01229-2
24 https://doi.org/10.1016/s0898-6568(00)00108-x
25 https://doi.org/10.1016/s0957-4166(97)00191-2
26 https://doi.org/10.1016/s0968-0896(99)00203-5
27 https://doi.org/10.1021/jm00178a014
28 https://doi.org/10.1021/jo071202h
29 https://doi.org/10.1021/op010223p
30 https://doi.org/10.1038/sj.bjp.0703780
31 https://doi.org/10.1042/0264-6021:3480273
32 https://doi.org/10.1055/s-1992-26307
33 https://doi.org/10.1074/jbc.273.10.5542
34 https://doi.org/10.1074/jbc.m211074200
35 https://doi.org/10.1083/jcb.144.4.745
36 https://doi.org/10.1083/jcb.150.4.797
37 https://doi.org/10.1097/00005344-200002000-00005
38 https://doi.org/10.1097/00005344-200211000-00013
39 https://doi.org/10.1097/00006123-200002000-00033
40 https://doi.org/10.1126/science.1090154
41 https://doi.org/10.1126/science.275.5304.1308
42 https://doi.org/10.1136/hrt.2003.029470
43 https://doi.org/10.1152/japplphysiol.01104.2004
44 https://doi.org/10.1161/01.cir.0000127939.16111.58
45 https://doi.org/10.1161/01.hyp.35.1.313
46 https://doi.org/10.1161/01.res.0000078780.65824.8b
47 https://doi.org/10.1161/01.res.84.10.1186
48 https://doi.org/10.1161/01.res.87.3.195
49 https://doi.org/10.1161/circulationaha.104.510248
50 https://doi.org/10.1161/hc1002.105938
51 https://doi.org/10.1165/ajrcmb.20.6.3441
52 https://doi.org/10.1177/1087057104264175
53 https://doi.org/10.1248/cpb.42.57
54 https://doi.org/10.1358/dnp.2005.18.10.959578
55 https://doi.org/10.2337/diabetes.49.12.2178
56 https://doi.org/10.3171/spi.2000.93.1.0094
57 schema:description <p num="p-0001">The invention relates to 6-substituted isoquinoline and isochinolone derivatives of the formula (I)</p><p num="p-0002"><chemistry id="CHEM-US-00001" num="00001"><img id="EMI-C00001" he="27.52mm" wi="62.91mm" file="US08278294-20121002-C00001.TIF" alt="embedded image" img-content="chem" img-format="tif" orientation="portrait" inline="no"/><attachments><attachment idref="CHEM-US-00001" attachment-type="cdx" file="US08278294-20121002-C00001.CDX"/><attachment idref="CHEM-US-00001" attachment-type="mol" file="US08278294-20121002-C00001.MOL"/></attachments></chemistry><br/> useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds. </p>
58 schema:keywords Myosin-Light-Chain Phosphatase
59 Rho
60 composition
61 compound
62 derivative
63 disease
64 formula
65 inhibitor
66 invention
67 mediated phosphorylation
68 prevention
69 rho-Associated Kinase
70 schema:name Substituted isoquinoline and isoquinolinone derivatives as inhibitors of Rho-kinase
71 schema:recipient https://www.grid.ac/institutes/grid.417924.d
72 schema:sameAs https://app.dimensions.ai/details/patent/US-8278294-B2
73 schema:sdDatePublished 2019-03-07T15:35
74 schema:sdLicense https://scigraph.springernature.com/explorer/license/
75 schema:sdPublisher Nb17e5d21229b454d9faaaba6103d2874
76 sgo:license sg:explorer/license/
77 sgo:sdDataset patents
78 rdf:type sgo:Patent
79 N39c0c83fb33346e1a6bddabc06ed7185 rdf:first Nc4eb84b2292f4e2b81b8259044cbb462
80 rdf:rest rdf:nil
81 N5b54baa28925415581d430e7ae20ea54 schema:name Joachim Brendel
82 rdf:type schema:Person
83 N5def3bc1cd514c2f9650c8ea0a1fd2c3 rdf:first Nc264c7b73dd542cd881284f4e78e4dec
84 rdf:rest Nba146e95f6c44595bd7b9ae399bb9f50
85 Nb17e5d21229b454d9faaaba6103d2874 schema:name Springer Nature - SN SciGraph project
86 rdf:type schema:Organization
87 Nba146e95f6c44595bd7b9ae399bb9f50 rdf:first N5b54baa28925415581d430e7ae20ea54
88 rdf:rest N39c0c83fb33346e1a6bddabc06ed7185
89 Nc264c7b73dd542cd881284f4e78e4dec schema:name Armin Hofmeister
90 rdf:type schema:Person
91 Nc4eb84b2292f4e2b81b8259044cbb462 schema:name Matthias Lohn
92 rdf:type schema:Person
93 Nc5fa915ada454bb5a4ee4f0658d1804a schema:name Oliver Plettenburg
94 rdf:type schema:Person
95 Nf6aaa62978f5410abfc091364f0e1596 rdf:first Nc5fa915ada454bb5a4ee4f0658d1804a
96 rdf:rest N5def3bc1cd514c2f9650c8ea0a1fd2c3
97 anzsrc-for:2464 schema:inDefinedTermSet anzsrc-for:
98 rdf:type schema:DefinedTerm
99 sg:pub.10.1038/40187 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014459412
100 https://doi.org/10.1038/40187
101 rdf:type schema:CreativeWork
102 sg:pub.10.1038/83258 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036056981
103 https://doi.org/10.1038/83258
104 rdf:type schema:CreativeWork
105 sg:pub.10.1038/nm1060 schema:sameAs https://app.dimensions.ai/details/publication/pub.1008244498
106 https://doi.org/10.1038/nm1060
107 rdf:type schema:CreativeWork
108 https://doi.org/10.1006/bbrc.1999.1129 schema:sameAs https://app.dimensions.ai/details/publication/pub.1001678672
109 rdf:type schema:CreativeWork
110 https://doi.org/10.1006/bbrc.2000.2315 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021388923
111 rdf:type schema:CreativeWork
112 https://doi.org/10.1006/bbrc.2000.2343 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044162166
113 rdf:type schema:CreativeWork
114 https://doi.org/10.1016/j.bbapap.2005.06.015 schema:sameAs https://app.dimensions.ai/details/publication/pub.1044932832
115 rdf:type schema:CreativeWork
116 https://doi.org/10.1016/j.bmc.2004.02.025 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028659501
117 rdf:type schema:CreativeWork
118 https://doi.org/10.1016/j.bmc.2006.09.052 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039348608
119 rdf:type schema:CreativeWork
120 https://doi.org/10.1016/j.bmc.2006.10.028 schema:sameAs https://app.dimensions.ai/details/publication/pub.1040282186
121 rdf:type schema:CreativeWork
122 https://doi.org/10.1016/j.cmet.2005.06.011 schema:sameAs https://app.dimensions.ai/details/publication/pub.1045928669
123 rdf:type schema:CreativeWork
124 https://doi.org/10.1016/j.ejphar.2005.03.001 schema:sameAs https://app.dimensions.ai/details/publication/pub.1019606213
125 rdf:type schema:CreativeWork
126 https://doi.org/10.1016/j.ejphar.2005.10.018 schema:sameAs https://app.dimensions.ai/details/publication/pub.1021280840
127 rdf:type schema:CreativeWork
128 https://doi.org/10.1016/j.neuroscience.2004.10.022 schema:sameAs https://app.dimensions.ai/details/publication/pub.1037010762
129 rdf:type schema:CreativeWork
130 https://doi.org/10.1016/j.tetlet.2003.09.111 schema:sameAs https://app.dimensions.ai/details/publication/pub.1004451980
131 rdf:type schema:CreativeWork
132 https://doi.org/10.1016/s0014-2999(00)00593-8 schema:sameAs https://app.dimensions.ai/details/publication/pub.1014226389
133 rdf:type schema:CreativeWork
134 https://doi.org/10.1016/s0014-2999(99)00891-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049451145
135 rdf:type schema:CreativeWork
136 https://doi.org/10.1016/s0014-5793(99)01762-7 schema:sameAs https://app.dimensions.ai/details/publication/pub.1036369220
137 rdf:type schema:CreativeWork
138 https://doi.org/10.1016/s0021-9150(00)00585-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1039629074
139 rdf:type schema:CreativeWork
140 https://doi.org/10.1016/s0024-3205(00)00781-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005152800
141 rdf:type schema:CreativeWork
142 https://doi.org/10.1016/s0024-3205(01)01229-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043670828
143 rdf:type schema:CreativeWork
144 https://doi.org/10.1016/s0898-6568(00)00108-x schema:sameAs https://app.dimensions.ai/details/publication/pub.1021232407
145 rdf:type schema:CreativeWork
146 https://doi.org/10.1016/s0957-4166(97)00191-2 schema:sameAs https://app.dimensions.ai/details/publication/pub.1020735778
147 rdf:type schema:CreativeWork
148 https://doi.org/10.1016/s0968-0896(99)00203-5 schema:sameAs https://app.dimensions.ai/details/publication/pub.1016280749
149 rdf:type schema:CreativeWork
150 https://doi.org/10.1021/jm00178a014 schema:sameAs https://app.dimensions.ai/details/publication/pub.1055937922
151 rdf:type schema:CreativeWork
152 https://doi.org/10.1021/jo071202h schema:sameAs https://app.dimensions.ai/details/publication/pub.1034962313
153 rdf:type schema:CreativeWork
154 https://doi.org/10.1021/op010223p schema:sameAs https://app.dimensions.ai/details/publication/pub.1029472773
155 rdf:type schema:CreativeWork
156 https://doi.org/10.1038/sj.bjp.0703780 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038114477
157 rdf:type schema:CreativeWork
158 https://doi.org/10.1042/0264-6021:3480273 schema:sameAs https://app.dimensions.ai/details/publication/pub.1056714768
159 rdf:type schema:CreativeWork
160 https://doi.org/10.1055/s-1992-26307 schema:sameAs https://app.dimensions.ai/details/publication/pub.1057394717
161 rdf:type schema:CreativeWork
162 https://doi.org/10.1074/jbc.273.10.5542 schema:sameAs https://app.dimensions.ai/details/publication/pub.1026994523
163 rdf:type schema:CreativeWork
164 https://doi.org/10.1074/jbc.m211074200 schema:sameAs https://app.dimensions.ai/details/publication/pub.1043307681
165 rdf:type schema:CreativeWork
166 https://doi.org/10.1083/jcb.144.4.745 schema:sameAs https://app.dimensions.ai/details/publication/pub.1022866344
167 rdf:type schema:CreativeWork
168 https://doi.org/10.1083/jcb.150.4.797 schema:sameAs https://app.dimensions.ai/details/publication/pub.1038018222
169 rdf:type schema:CreativeWork
170 https://doi.org/10.1097/00005344-200002000-00005 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060206946
171 rdf:type schema:CreativeWork
172 https://doi.org/10.1097/00005344-200211000-00013 schema:sameAs https://app.dimensions.ai/details/publication/pub.1018127331
173 rdf:type schema:CreativeWork
174 https://doi.org/10.1097/00006123-200002000-00033 schema:sameAs https://app.dimensions.ai/details/publication/pub.1060250588
175 rdf:type schema:CreativeWork
176 https://doi.org/10.1126/science.1090154 schema:sameAs https://app.dimensions.ai/details/publication/pub.1062448978
177 rdf:type schema:CreativeWork
178 https://doi.org/10.1126/science.275.5304.1308 schema:sameAs https://app.dimensions.ai/details/publication/pub.1023493290
179 rdf:type schema:CreativeWork
180 https://doi.org/10.1136/hrt.2003.029470 schema:sameAs https://app.dimensions.ai/details/publication/pub.1005770183
181 rdf:type schema:CreativeWork
182 https://doi.org/10.1152/japplphysiol.01104.2004 schema:sameAs https://app.dimensions.ai/details/publication/pub.1028089859
183 rdf:type schema:CreativeWork
184 https://doi.org/10.1161/01.cir.0000127939.16111.58 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012182298
185 rdf:type schema:CreativeWork
186 https://doi.org/10.1161/01.hyp.35.1.313 schema:sameAs https://app.dimensions.ai/details/publication/pub.1049690454
187 rdf:type schema:CreativeWork
188 https://doi.org/10.1161/01.res.0000078780.65824.8b schema:sameAs https://app.dimensions.ai/details/publication/pub.1021821469
189 rdf:type schema:CreativeWork
190 https://doi.org/10.1161/01.res.84.10.1186 schema:sameAs https://app.dimensions.ai/details/publication/pub.1012623433
191 rdf:type schema:CreativeWork
192 https://doi.org/10.1161/01.res.87.3.195 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007984386
193 rdf:type schema:CreativeWork
194 https://doi.org/10.1161/circulationaha.104.510248 schema:sameAs https://app.dimensions.ai/details/publication/pub.1010793417
195 rdf:type schema:CreativeWork
196 https://doi.org/10.1161/hc1002.105938 schema:sameAs https://app.dimensions.ai/details/publication/pub.1041921770
197 rdf:type schema:CreativeWork
198 https://doi.org/10.1165/ajrcmb.20.6.3441 schema:sameAs https://app.dimensions.ai/details/publication/pub.1007741147
199 rdf:type schema:CreativeWork
200 https://doi.org/10.1177/1087057104264175 schema:sameAs https://app.dimensions.ai/details/publication/pub.1013582821
201 rdf:type schema:CreativeWork
202 https://doi.org/10.1248/cpb.42.57 schema:sameAs https://app.dimensions.ai/details/publication/pub.1052992913
203 rdf:type schema:CreativeWork
204 https://doi.org/10.1358/dnp.2005.18.10.959578 schema:sameAs https://app.dimensions.ai/details/publication/pub.1065057677
205 rdf:type schema:CreativeWork
206 https://doi.org/10.2337/diabetes.49.12.2178 schema:sameAs https://app.dimensions.ai/details/publication/pub.1051306915
207 rdf:type schema:CreativeWork
208 https://doi.org/10.3171/spi.2000.93.1.0094 schema:sameAs https://app.dimensions.ai/details/publication/pub.1071103218
209 rdf:type schema:CreativeWork
210 https://www.grid.ac/institutes/grid.417924.d schema:Organization
 




Preview window. Press ESC to close (or click here)


...