Substituted pyrimidines useful as protein kinase inhibitors


Ontology type: sgo:Patent     


Patent Info

DATE

2012-09-18T00:00

AUTHORS

CHARRIER JEAN-DAMIEN , MAZZEI FRANCESCA , KAY DAVID , MILLER ANDREW

ABSTRACT

The present invention provides a facile process for the preparation of tri- and tetra-substituted pyrimidines. The process is useful for preparing inhibitors of protein kinases, especially Aurora kinase. These inhibitors are useful for treating or lessening the severity of Aurora-mediated diseases or conditions.

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