Methods and means for obtaining modified phenotypes


Ontology type: sgo:Patent     


Patent Info

DATE

2012-05-22T00:00

AUTHORS

Peter Michael Waterhouse , Ming-Bo Wang

ABSTRACT

Methods and means are provided for reducing the phenotypic expression of a nucleic acid of interest in eukaryotic cells by providing aberrant, preferably unpolyadenylated, target-specific RNA to the nucleus of the host cell. Preferably, the unpolyadenylated, target-specific RNA is provided by transcription of a chimeric gene comprising a promoter and a DNA region encoding the target-specific RNA. More... »

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