Fusion protein of an exendin to modified transferrin


Ontology type: sgo:Patent     


Patent Info

DATE

2012-04-17T00:00

AUTHORS

David James Ballance , Christopher P. Prior , Homayoun Sadeghi , Andrew J. Turner

ABSTRACT

The invention provides fusion proteins comprising an exendin-4 fused to a transferrin (Tf) via a polypeptide linker, as well as corresponding nucleic acid molecules, vectors, host cells, and pharmaceutical compositions. The invention also provides the use of the exendin-4/Tf fusion proteins for treatment of Type II diabetes, obesity, and to reduce body weight. More... »

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