9-(piperazinylalkyl) carbazoles as bax-modulators


Ontology type: sgo:Patent     


Patent Info

DATE

2011-11-08T00:00

AUTHORS

Serge Halazy , Dennis Church , Bruno Antonsson , Agnes Bombrun , Patrick Gerber , Jean-Claude Martinou

ABSTRACT

The present invention is related to piperazine derivatives of carbazole of formula (I) notably for use as pharmaceutically active compounds, as well as to pharmaceutical formulations containing such piperazine derivatives of carbazole. Said piperazine derivatives of carbazole are efficient modulators, in particular efficient inhibitors, of the Bax function and/or activation. The present invention is furthermore related to novel piperazine derivatives of carbazole as well as methods of their preparation. More... »

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