Integration-site directed vector systems


Ontology type: sgo:Patent     


Patent Info

DATE

2011-04-05T00:00

AUTHORS

Perry B. Hackett , Jeffrey Essner

ABSTRACT

Some aspects of the application describe materials and methods for making a molecular tether. A molecular tether, in certain embodiments, includes a target-DNA-binding domain having a specific binding affinity for a target-DNA segment in a host chromosome, a carrier-binding domain that specifically binds to a DNA segment on a carrier, and a spacer covalently bonded to the target DNA-binding domain and the carrier-binding domain. More... »

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