Method for designing surfaces


Ontology type: sgo:Patent     


Patent Info

DATE

2011-02-01T00:00

AUTHORS

Alain-Dominique Jean-Pierre Gorse

ABSTRACT

A method of producing a binding surface for a target molecule having a functional binding site, which method comprises: (i) identifying within the target molecule an anchor site which is remote from the functional binding site; (ii) generating a pharmacophore model for the anchor site; (iii) using the pharmacophore model to identify an anchor site binding ligand; and (iv) providing the anchor site binding ligand on a surface of a substrate such that the ability of the anchor site binding ligand to bind to the anchor site is preserved. More... »

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