Methods and systems to identify operational reaction pathways


Ontology type: sgo:Patent     


Patent Info

DATE

2011-01-11T00:00

AUTHORS

Bernhard O. Palsson , Markus W. Covert , Markus Herrgard

ABSTRACT

The present invention provides a method of refining a biosystem reaction network. The method consists of: (a) providing a mathematical representation of a biosystem; (b) reconciling said mathematical representation of said biosystem; (c) determining differences between observed behavior of a biosystem and in silico behavior of said mathematical representation of said biosystem under similar conditions; (d) modifying a structure of said mathematical representation of said biosystem, and (e) determining differences between said observed behavior of said biosystem and in silico behavior of said modified mathematical representation of said biosystem under similar conditions. More... »

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